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In OVX and OVX+ ADDWoR groups, bilateral OVX was performed and then the serum level of 17\u03b2-estradiol was evaluated every week. In ADDWoR group and OVX+ ADDWoR group, the right TMJ was surgically opened and the disc was displaced anteriorly and the left TMJ was also surgically opened and closed without any manipulation of the disc. All rabbits had CT scan before and at the end of the study and the mandible measurements were performed on the 3D-reconstructed model. The mandible in ADDWoR group was consistently shorter on the right side resulting in a midline shift to the ipsilateral side. While in OVX+ ADDWoR group, the mandibular length of the right side was more shorter than in ADDWoR group, moreover, mandibular deviation was therefore more severe. In OVX group, there was no difference regarding the length of mandible compared to the control group. There was no difference regarding the mandibular length between left and right sides in the control group.<\/jats:p>","DOI":"10.1038\/s41598-018-34023-4","type":"journal-article","created":{"date-parts":[[2018,10,17]],"date-time":"2018-10-17T11:33:22Z","timestamp":1539776002000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Experimental study on mandibular length and facial symmetry of low estrogen level and anterior disc displacement of temporomandibular joint"],"prefix":"10.1038","volume":"8","author":[{"given":"Zixian","family":"Jiao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiangyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2018,10,23]]},"reference":[{"key":"34023_CR1","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1016\/j.jcms.2016.01.019","volume":"44","author":"Q Xie","year":"2016","unstructured":"Xie, Q. et al. 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