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To address this possibility, the presence of ZIKV neutralizing antibodies was determined in serum from 135 healthy Thai adults with a plaque reduction neutralization test (PRNT), and a number of samples were subsequently analyzed for the presence of neutralizing antibodies to dengue virus (DENV) and Japanese encephalitis virus (JEV). Results showed that 70.4% (PRNT\n                    <jats:sub>50<\/jats:sub>\n                    \u2009\u2265\u200910), 55.6 (PRNT\n                    <jats:sub>50<\/jats:sub>\n                    \u2009\u2265\u200920) or 22.2% (PRNT\n                    <jats:sub>90<\/jats:sub>\n                    \u2009\u2265\u200920) of the samples showed neutralizing antibodies to ZIKV. Detailed analysis showed no association between the presence of neutralizing antibodies to other flaviviruses (DENV, JEV) and the presence of ZIKV neutralizing antibodies. These results suggest that the level of ZIKV neutralizing antibodies in the Thai population is enough to dampen the transmission of the virus in Thailand.\n                  <\/jats:p>","DOI":"10.1038\/s41598-018-35643-6","type":"journal-article","created":{"date-parts":[[2018,11,15]],"date-time":"2018-11-15T07:21:57Z","timestamp":1542266517000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Analysis of Zika virus neutralizing antibodies in normal healthy Thais"],"prefix":"10.1038","volume":"8","author":[{"given":"Wannapa","family":"Sornjai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janejira","family":"Jaratsittisin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prasert","family":"Auewarakul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitwara","family":"Wikan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6592-9852","authenticated-orcid":false,"given":"Duncan R.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,11,21]]},"reference":[{"key":"35643_CR1","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/0035-9203(52)90042-4","volume":"46","author":"GW Dick","year":"1952","unstructured":"Dick, G. 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