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Total 29 patients diagnosed with unilateral definite MD were enrolled. All patients underwent IV-Gd inner ear MRI and auditory and vestibular function tests such as pure tone audiometry (PTA), electrocochleography (ECoG), cervical vestibular evoked myogenic potential (cVEMP) and caloric test. The hydrops ratio in the cochlea and vestibule were significantly higher in the affected side than the unaffected side (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Average pure-tone thresholds for 0.5, 1\u2009k, 2\u2009k, and 4\u2009k Hz correlated significantly with cochlear and vestibular hydrops (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01) in the affected side. When comparing the SP\/AP ratio of ECoG with hydrops ratio in the vestibule, the affected and unaffected ears showed a significant difference (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Similarly, the results of the caloric test also showed a significant correlation (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) with relative vestibular hydrops. However, the cVEMP response was not related to the hydrops ratio in the cochlea or vestibule. This study presents pertinent data with appropriate correlations with auditory vestibular functional testing which demonstrates the usefulness of IV-Gd inner ear MRI as a diagnostic method for visualizing the endolymphatic hydrops in MD.<\/jats:p>","DOI":"10.1038\/s41598-018-35709-5","type":"journal-article","created":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T17:55:56Z","timestamp":1543341356000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Usefulness of Intravenous Gadolinium Inner Ear MR Imaging in Diagnosis of M\u00e9ni\u00e8re\u2019s Disease"],"prefix":"10.1038","volume":"8","author":[{"given":"Young Sang","family":"Cho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung Min","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8105-813X","authenticated-orcid":false,"given":"Ji Eun","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Woo","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Kyung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyung-Jin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won-Ho","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,12,3]]},"reference":[{"key":"35709_CR1","doi-asserted-by":"crossref","unstructured":"Committee on Hearing and Equilibrium. 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