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Experiments were performed on a group of 20 healthy volunteers (8 males and 12 females; age 25.3\u2009\u00b1\u20097.9 years; BMI\u2009=\u200922.1\u2009\u00b1\u20093.2\u2009kg\/m<jats:sup>2<\/jats:sup>). BP and heart rate (HR) were measured using continuous finger-pulse photoplethysmography. SAS signals were recorded using an SAS monitor. Oxyhaemoglobin saturation (SaO<jats:sub>2<\/jats:sub>) and end-tidal CO<jats:sub>2<\/jats:sub>(EtCO<jats:sub>2<\/jats:sub>) were measured using a medical monitoring system. Procedure 1 consisted of breathing spontaneously and at controlled rates of 6 breaths\/minute and 6 breaths\/minute with inspiratory resistance for 10\u2009minutes. Procedure 2 consisted of breathing spontaneously and at controlled rates of 6, 12 and 18 breaths\/minute for 5\u2009minutes. Wavelet analysis with the Morlet mother wavelet was applied for delineation of BP and SAS signals cardiac and respiratory components. Slow breathing diminishes amplitude of cardiac BP and SAS oscillations. The overall increase in BP and SAS oscillations during slow breathing is driven by the respiratory component. Drop in cardiac component of BP amplitude evoked by slow-breathing may be perceived as a cardiovascular protective mechanism to avoid target organ damage. Further studies are warranted to assess long-term effects of slow breathing.<\/jats:p>","DOI":"10.1038\/s41598-019-42552-9","type":"journal-article","created":{"date-parts":[[2019,4,17]],"date-time":"2019-04-17T10:14:19Z","timestamp":1555496059000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Impact of slow breathing on the blood pressure and subarachnoid space width oscillations in humans"],"prefix":"10.1038","volume":"9","author":[{"given":"Magdalena K.","family":"Nuckowska","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcin","family":"Gruszecki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacek","family":"Kot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacek","family":"Wolf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Guminski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrzej F.","family":"Frydrychowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerzy","family":"Wtorek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krzysztof","family":"Narkiewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawel J.","family":"Winklewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,4,17]]},"reference":[{"key":"42552_CR1","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1183\/20734735.009817","volume":"13","author":"MA Russo","year":"2012","unstructured":"Russo, M. 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