{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T17:26:13Z","timestamp":1763141173351,"version":"3.37.3"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T00:00:00Z","timestamp":1557360000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T00:00:00Z","timestamp":1557360000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100007551","name":"Hallym University Medical Center","doi-asserted-by":"publisher","award":["HURF-2019-15"],"award-info":[{"award-number":["HURF-2019-15"]}],"id":[{"id":"10.13039\/501100007551","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>An association between sleep duration and a wide spectrum of diseases has been reported, but little is known about its relationship with chronic rhinosinusitis (CRS). The present study aimed to investigate whether sleep duration was associated with CRS after adjusting for potential confounding factors in Korean adults. We analyzed data from the Korea National Health and Nutrition Examination Survey 2005\u20132009 and enrolled 24,658 participants aged \u226520 years. Data regarding sociodemographic characteristics, self-reported sleep duration, CRS, and other medical diseases were collected from questionnaires. Multiple logistic regression analyses were used to identify the relationship between sleep duration and CRS. The overall prevalence of CRS was 4.4%. Subjects with sleep duration \u22645\u2009hours showed a highest prevalence for CRS (6.1%), compared to subjects with longer sleep duration (<jats:italic>p<\/jats:italic>\u2009=\u20090.02). After adjusting for covariates (age, sex, household income, residency, dwelling type, education, depression, alcohol, allergic rhinitis, chronic otitis media, angina or myocardial infarction, asthma, chronic obstructive pulmonary disease, bronchiectasis, and gastric ulcer), the sleep duration of \u22645\u2009hours was significantly associated with CRS (OR\u2009=\u20091.502; 95% CI\u2009=\u20091.164\u20131.938). Only in older subgroup (\u226550 years old), shorter sleep duration (\u22645\u2009hours) showed higher odds for CRS. These results suggested that sleep duration may be negatively associated with CRS in older Korean adults.<\/jats:p>","DOI":"10.1038\/s41598-019-43585-w","type":"journal-article","created":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T10:59:00Z","timestamp":1557399540000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Association between Sleep Duration and Chronic Rhinosinusitis among the Korean General Adult Population: Korea National Health and Nutrition Examination Survey"],"prefix":"10.1038","volume":"9","author":[{"given":"Jeong-Whun","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hahn Jin","family":"Jung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1655-9549","authenticated-orcid":false,"given":"Hyo Geun","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chae-Seo","family":"Rhee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6513-7011","authenticated-orcid":false,"given":"Jee Hye","family":"Wee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,5,9]]},"reference":[{"key":"43585_CR1","doi-asserted-by":"publisher","first-page":"1216","DOI":"10.1111\/j.1398-9995.2011.02646.x","volume":"66","author":"D Hastan","year":"2011","unstructured":"Hastan, D. et al. Chronic rhinosinusitis in Europe-an underestimated disease. A GA(2)LEN study. Allergy. 66, 1216\u20131223 (2011).","journal-title":"Allergy."},{"key":"43585_CR2","unstructured":"Fokkens, W. J. et al. European Position Paper on Rhinosinusitis and Nasal Polyps 2012. Rhinol Suppl. 23:3 p preceding table of contents, 1\u2013298 (2012)."},{"key":"43585_CR3","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1177\/194589240301700106","volume":"17","author":"N Bhattacharyya","year":"2003","unstructured":"Bhattacharyya, N. The economic burden and symptom manifestations of chronic rhinosinusitis. Am J Rhinol. 17, 27\u201332 (2003).","journal-title":"Am J Rhinol."},{"key":"43585_CR4","doi-asserted-by":"publisher","first-page":"37","DOI":"10.2147\/IJGM.S8077","volume":"3","author":"M Stewart","year":"2010","unstructured":"Stewart, M., Ferguson, B. & Fromer, L. Epidemiology and burden of nasal congestion. Int J Gen Med. 3, 37\u201345 (2010).","journal-title":"Int J Gen Med."},{"key":"43585_CR5","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.5664\/jcsm.5024","volume":"11","author":"Y Wang","year":"2015","unstructured":"Wang, Y. et al. Relationship between Duration of Sleep and Hypertension in Adults: A Meta-Analysis. JCSM. 11, 1047\u20131056 (2015).","journal-title":"JCSM."},{"key":"43585_CR6","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.smrv.2015.10.002","volume":"30","author":"T Anothaisintawee","year":"2016","unstructured":"Anothaisintawee, T., Reutrakul, S., Van Cauter, E. & Thakkinstian, A. Sleep disturbances compared to traditional risk factors for diabetes development: Systematic review and meta-analysis. Sleep Med Rev. 30, 11\u201324 (2016).","journal-title":"Sleep Med Rev."},{"key":"43585_CR7","doi-asserted-by":"publisher","first-page":"1487","DOI":"10.5665\/sleep.1382","volume":"34","author":"MP Hoevenaar-Blom","year":"2011","unstructured":"Hoevenaar-Blom, M. P., Spijkerman, A. M., Kromhout, D., van den Berg, J. F. & Verschuren, W. M. Sleep duration and sleep quality in relation to 12-year cardiovascular disease incidence: the MORGEN study. Sleep. 34, 1487\u20131492 (2011).","journal-title":"Sleep."},{"key":"43585_CR8","doi-asserted-by":"publisher","first-page":"956","DOI":"10.1093\/sleep\/33.7.956","volume":"33","author":"JE Gangwisch","year":"2010","unstructured":"Gangwisch, J. E. et al. Short sleep duration as a risk factor for hypercholesterolemia: analyses of the National Longitudinal Study of Adolescent Health. Sleep. 33, 956\u2013961 (2010).","journal-title":"Sleep."},{"key":"43585_CR9","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/j.smrv.2009.07.006","volume":"14","author":"MA Grandner","year":"2010","unstructured":"Grandner, M. A., Hale, L., Moore, M. & Patel, N. P. Mortality associated with short sleep duration: The evidence, the possible mechanisms, and the future. Sleep Med Rev. 14, 191\u2013203 (2010).","journal-title":"Sleep Med Rev."},{"key":"43585_CR10","doi-asserted-by":"publisher","first-page":"250","DOI":"10.1016\/j.diabres.2013.10.003","volume":"102","author":"KM Stefani","year":"2013","unstructured":"Stefani, K. M., Kim, H. C., Kim, J., Oh, K. & Suh, I. The influence of sex and age on the relationship between sleep duration and metabolic syndrome in Korean adults. Diabetes Res Clin Pract. 102, 250\u2013259 (2013).","journal-title":"Diabetes Res Clin Pract."},{"key":"43585_CR11","doi-asserted-by":"publisher","first-page":"e72507","DOI":"10.1371\/journal.pone.0072507","volume":"8","author":"JA Kwon","year":"2013","unstructured":"Kwon, J. A., Lee, M., Yoo, K. B. & Park, E. C. Does the duration and time of sleep increase the risk of allergic rhinitis? Results of the 6-year nationwide Korea youth risk behavior web-based survey. PloS One. 8, e72507 (2013).","journal-title":"PloS One."},{"key":"43585_CR12","doi-asserted-by":"crossref","first-page":"2364","DOI":"10.1002\/lary.24040","volume":"123","author":"JA Alt","year":"2013","unstructured":"Alt, J. A., Smith, T. L., Mace, J. C. & Soler, Z. M. Sleep quality and disease severity in patients with chronic rhinosinusitis. Laryngoscope. 123, 2364\u20132370 (2013).","journal-title":"Laryngoscope."},{"key":"43585_CR13","first-page":"873","volume":"141","author":"JA Alt","year":"2015","unstructured":"Alt, J. A. et al. Quality of life in patients with chronic rhinosinusitis and sleep dysfunction undergoing endoscopic sinus surgery: A pilot investigation of comorbid obstructive sleep apnea. JAMA Otolaryngol Head Neck Surg. 141, 873\u2013881 (2015).","journal-title":"JAMA Otolaryngol Head Neck Surg."},{"key":"43585_CR14","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1093\/sleep\/27.7.1255","volume":"27","author":"MM Ohayon","year":"2004","unstructured":"Ohayon, M. M., Carskadon, M. A., Guilleminault, C. & Vitiello, M. V. Meta-analysis of quantitative sleep parameters from childhood to old age in healthy individuals: developing normative sleep values across the human lifespan. Sleep. 27, 1255\u20131273 (2004).","journal-title":"Sleep."},{"key":"43585_CR15","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-015-2359-0","volume":"15","author":"M Cao","year":"2015","unstructured":"Cao, M. et al. Association between sleep duration and obesity is age- and gender-dependent in Chinese urban children aged 6\u201318 years: a cross-sectional study. BMC Public Health. 15, 1029 (2015).","journal-title":"BMC Public Health."},{"key":"43585_CR16","doi-asserted-by":"publisher","first-page":"1286","DOI":"10.1038\/ajh.2010.166","volume":"23","author":"J Kim","year":"2010","unstructured":"Kim, J. & Jo, I. Age-dependent association between sleep duration and hypertension in the adult Korean population. Am J Hypertens. 23, 1286\u20131291 (2010).","journal-title":"Am J Hypertens."},{"key":"43585_CR17","doi-asserted-by":"crossref","unstructured":"Bengtsson, C. et al. Chronic rhinosinusitis impairs sleep quality - results of the GA2LEN study. Sleep. 40 (2017).","DOI":"10.1016\/j.sleep.2017.11.082"},{"key":"43585_CR18","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1016\/j.anl.2015.10.006","volume":"43","author":"Y Ando","year":"2016","unstructured":"Ando, Y. et al. Risk factors for sleep impairment in adult patients with chronic rhinosinusitis. Auris Nasus Larynx. 43, 418\u2013421 (2016).","journal-title":"Auris Nasus Larynx."},{"key":"43585_CR19","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.amjoto.2007.06.002","volume":"29","author":"TJ Craig","year":"2008","unstructured":"Craig, T. J., Ferguson, B. J. & Krouse, J. H. Sleep impairment in allergic rhinitis, rhinosinusitis, and nasal polyposis. Am J Otolaryngol. 29, 209\u2013217 (2008).","journal-title":"Am J Otolaryngol."},{"key":"43585_CR20","doi-asserted-by":"publisher","DOI":"10.1038\/srep20786","volume":"6","author":"LT Kao","year":"2016","unstructured":"Kao, L. T. et al. Obstructive sleep apnea and the subsequent risk of chronic rhinosinusitis: A population-based study. Sci Rep. 6, 20786 (2016).","journal-title":"Sci Rep."},{"key":"43585_CR21","doi-asserted-by":"publisher","first-page":"54","DOI":"10.2174\/187221310789895568","volume":"4","author":"HM Inancli","year":"2010","unstructured":"Inancli, H. M. & Enoz, M. Obstructive sleep apnea syndrome and upper airway inflammation. Recent Pat Inflamm Allergy Drug Discov. 4, 54\u201357 (2010).","journal-title":"Recent Pat Inflamm Allergy Drug Discov."},{"key":"43585_CR22","doi-asserted-by":"publisher","first-page":"1905","DOI":"10.5665\/sleep.5238","volume":"38","author":"T Kanagasabai","year":"2015","unstructured":"Kanagasabai, T. & Ardern, C. I. Contribution of Inflammation, Oxidative Stress, and Antioxidants to the Relationship between Sleep Duration and Cardiometabolic Health. Sleep. 38, 1905\u20131912 (2015).","journal-title":"Sleep."},{"key":"43585_CR23","doi-asserted-by":"publisher","first-page":"1361","DOI":"10.5665\/sleep.5964","volume":"39","author":"T DeMartino","year":"2016","unstructured":"DeMartino, T. et al. Oxidative stress and inflammation differentially elevated in objective versus habitual subjective reduced sleep duration in obstructive sleep apnea. Sleep. 39, 1361\u20131369 (2016).","journal-title":"Sleep."},{"key":"43585_CR24","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1001\/archotol.1997.01900020089013","volume":"123","author":"GJ Westerveld","year":"1997","unstructured":"Westerveld, G. J., Dekker, I., Voss, H. P., Bast, A. & Scheeren, R. A. Antioxidant Levels in the Nasal Mucosa of Patients With Chronic Sinusitis and Healthy Controls. Arch Otolaryngol Head Neck Surg. 123, 201\u2013204 (1997).","journal-title":"Arch Otolaryngol Head Neck Surg."},{"key":"43585_CR25","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1046\/j.1365-2869.1999.00155.x","volume":"8","author":"SW Lockley","year":"1999","unstructured":"Lockley, S. W., Skene, D. J. & Arendt, J. Comparison between subjective and actigraphic measurement of sleep and sleep rhythms. J Sleep Res. 8, 175\u2013178 (1999).","journal-title":"J Sleep Res."},{"key":"43585_CR26","doi-asserted-by":"publisher","first-page":"e62725","DOI":"10.1371\/journal.pone.0062725","volume":"8","author":"WH Lee","year":"2013","unstructured":"Lee, W. H. et al. Prevalence of subjective olfactory dysfunction and its risk factors: Korean national health and nutrition examination survey. PLoS One. 8, e62725 (2013).","journal-title":"PLoS One."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-019-43585-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-019-43585-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-019-43585-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T11:49:33Z","timestamp":1694864973000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-019-43585-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,9]]},"references-count":26,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,12]]}},"alternative-id":["43585"],"URL":"https:\/\/doi.org\/10.1038\/s41598-019-43585-w","relation":{},"ISSN":["2045-2322"],"issn-type":[{"type":"electronic","value":"2045-2322"}],"subject":[],"published":{"date-parts":[[2019,5,9]]},"assertion":[{"value":"12 November 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 April 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 May 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}],"article-number":"7158"}}