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A longitudinal study was conducted to investigate the carriage and density of these bacteria in the nasal passages of healthy beef calves (N\u2009=\u200960) housed over winter in an experimental farm setting. The three pathobiont species exhibited remarkably different carriage rates and density profiles. At housing, high carriage rates were observed for <jats:italic>P<\/jats:italic>. <jats:italic>multocida<\/jats:italic> (95%), and <jats:italic>H<\/jats:italic>. <jats:italic>somni<\/jats:italic> (75%), while fewer calves were positive for <jats:italic>M<\/jats:italic>. <jats:italic>haemolytica<\/jats:italic> (13%). Carriage rates for all three bacterial species declined over the 75-day study, but not all individuals became colonised despite sharing of environment and airspace. Colonisation patterns ranged from continuous to intermittent and were different among pathobiont species. Interval-censored exponential survival models estimated the median duration of <jats:italic>H<\/jats:italic>. <jats:italic>somni<\/jats:italic> and <jats:italic>P<\/jats:italic>. <jats:italic>multocida<\/jats:italic> carriage at 14.8 (CI<jats:sub>95%<\/jats:sub>: 10.6\u201320.9) and 55.5 (CI<jats:sub>95%<\/jats:sub>: 43.3\u201371.3) days respectively, and found higher density <jats:italic>P<\/jats:italic>. <jats:italic>multocida<\/jats:italic> carriage was associated with slower clearance (p\u2009=\u20090.036). This work offers insights into the dynamics of pathobiont carriage and provides a potential platform for further data collection and modelling studies.<\/jats:p>","DOI":"10.1038\/s41598-019-48007-5","type":"journal-article","created":{"date-parts":[[2019,8,16]],"date-time":"2019-08-16T10:14:59Z","timestamp":1565950499000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Insights into Pasteurellaceae carriage dynamics in the nasal passages of healthy beef calves"],"prefix":"10.1038","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2658-4126","authenticated-orcid":false,"given":"A. C.","family":"Thomas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Bailey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. R. 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