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These MRI-based topographic maps are not easily applicable to CT scans, because the standard-reference-lines for axial image orientation (i.e., anterior-posterior commissure line versus orbito-meatal line, respectively) are \u2018not parallel\u2019 to each other. Moreover, current, widely-used CT-based vascular topographic diagrams omit demarcation of the inter-territorial border-zones. Thus, we aimed to generate a CT-specific high-resolution atlas, showing the supratentorial cerebrovascular territories and the inter-territorial border-zones in a statistically rigorous way. The diffusion-weighted MRI lesion atlas is based on 1160 patients (67.0\u2009\u00b1\u200913.3 years old, 53.7% men) with acute (&lt;1-week) cerebral infarction due to significant (&gt;50%) stenosis or occlusion of a single large cerebral artery: anterior, middle, or posterior cerebral artery. We developed a software package enabling the transformation of our MR-based atlas into a re-oriented CT space corresponding to the axial slice orientations used in clinical practice. Infarct volumes are individually mapped to the three vascular territories on the CT template-set, generating brain maps showing the voxelwise frequency of infarct by the affected parent vessel. We then mapped the three vascular territories collectively, generating a dataset of Certainty-Index (CI) maps to reflect the likelihood of a voxel being a member of a specific vascular territory. Border-zones could be defined by using either relative infarct frequencies or CI differences. The topographic vascular territory atlas, revised for CT, will allow for easier and more accurate delineation of arterial territories and borders on CT images.<\/jats:p>","DOI":"10.1038\/s41598-019-48266-2","type":"journal-article","created":{"date-parts":[[2019,8,12]],"date-time":"2019-08-12T10:03:15Z","timestamp":1565604195000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Supratentorial Cerebral Arterial Territories for Computed Tomograms: A Mapping Study in 1160 Large Artery Infarcts"],"prefix":"10.1038","volume":"9","author":[{"given":"Dong-Eog","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0042-9304","authenticated-orcid":false,"given":"Jinseong","family":"Jang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dawid","family":"Schellingerhout","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2823-5253","authenticated-orcid":false,"given":"Wi-Sun","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong-Ho","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su-Kyoung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongmin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee-Joon","family":"Bae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,8,12]]},"reference":[{"key":"48266_CR1","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1001\/jamaneurol.2018.2808","volume":"76","author":"DE Kim","year":"2019","unstructured":"Kim, D. E. et al. Mapping the Supratentorial Cerebral Arterial Territories Using 1160 Large Artery Infarcts. JAMA Neurol 76, 72\u201380, https:\/\/doi.org\/10.1001\/jamaneurol.2018.2808 (2019).","journal-title":"JAMA Neurol"},{"key":"48266_CR2","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1111\/ijs.12199","volume":"9","author":"BJ Kim","year":"2014","unstructured":"Kim, B. J. et al. Current status of acute stroke management in Korea: a report on a multicenter, comprehensive acute stroke registry. Int J Stroke 9, 514\u2013518, https:\/\/doi.org\/10.1111\/ijs.12199 (2014).","journal-title":"Int J Stroke"},{"key":"48266_CR3","first-page":"922","volume":"24","author":"KL Weiss","year":"2003","unstructured":"Weiss, K. L. et al. Clinical brain MR imaging prescriptions in Talairach space: technologist- and computer-driven methods. AJNR Am J Neuroradiol 24, 922\u2013929 (2003).","journal-title":"AJNR Am J Neuroradiol"},{"key":"48266_CR4","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1148\/radiology.184.1.1609066","volume":"184","author":"LJ Yeoman","year":"1992","unstructured":"Yeoman, L. J., Howarth, L., Britten, A., Cotterill, A. & Adam, E. J. Gantry angulation in brain CT: dosage implications, effect on posterior fossa artifacts, and current international practice. Radiology 184, 113\u2013116, https:\/\/doi.org\/10.1148\/radiology.184.1.1609066 (1992).","journal-title":"Radiology"},{"key":"48266_CR5","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1007\/BF02283018","volume":"7","author":"M Savoiardo","year":"1986","unstructured":"Savoiardo, M. The vascular territories of the carotid and vertebrobasilar systems. Diagrams based on CT studies of infarcts. 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