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We aimed to compare the benefits and drawbacks of LRH and open approaches. Between January 2014 and October 2017, 85 patients with tumor and hepatolithiasis who underwent LRH (<jats:italic>n\u2009=\u2009<\/jats:italic>30) and open right hemihepatectomy (ORH) (<jats:italic>n\u2009=\u2009<\/jats:italic>55) were enrolled in this study. For tumors, LRH showed significantly better results with respect to blood loss (<jats:italic>P<\/jats:italic>\u2009=\u20090.024) and duration of hospital stay (<jats:italic>P<\/jats:italic>\u2009=\u20090.008) than ORH, while hospital expenses (<jats:italic>P<\/jats:italic>\u2009=\u20090.031) and bile leakage rate (<jats:italic>P<\/jats:italic>\u2009=\u20090.012) were higher with LRH. However, the operative time and rate of other complications were not significantly different between the two groups. However, for hepatolithiasis, there was less blood loss (<jats:italic>P<\/jats:italic>\u2009=\u20090.015) and longer operative time (<jats:italic>P<\/jats:italic>\u2009=\u20090.036) with LRH than with ORH. There were no significant difference between LRH and ORH in terms of hospital stay, hospital expenses, and complication rate (<jats:italic>P<\/jats:italic>\u2009&gt;\u20090.05). Moreover, the postoperative white blood cell count, alanine aminotransferase level, aspartate aminotransferase level, and total bilirubin were not significantly different in both types of patients (<jats:italic>P<\/jats:italic>\u2009&gt;\u20090.05). Our results suggest the safety and feasibility of laparoscopy technology for right hemihepatectomy in both tumor and hepatolithiasis patients.<\/jats:p>","DOI":"10.1038\/s41598-019-52694-5","type":"journal-article","created":{"date-parts":[[2019,12,11]],"date-time":"2019-12-11T12:44:58Z","timestamp":1576068298000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Safety and feasibility of laparoscopy technology in right hemihepatectomy"],"prefix":"10.1038","volume":"9","author":[{"given":"Xin","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilai","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yupeng","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingwen","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,12,11]]},"reference":[{"key":"52694_CR1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-24787-0","volume":"8","author":"SM Xie","year":"2018","unstructured":"Xie, S. 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