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By 2014 the virus reached Eastern Island in the Americas, and two years later, the virus spread to almost all countries and territories of the Americas. The mosquito <jats:italic>Aedes aegypti<\/jats:italic> has been identified as the main vector of the disease, and several researchers have also studied the vector competence of <jats:italic>Culex quinquefasciatus<\/jats:italic> in virus transmission. The aim of the present study was to evaluate the vector competence of <jats:italic>Ae<\/jats:italic>. <jats:italic>aegypti<\/jats:italic> and <jats:italic>Cx<\/jats:italic>. <jats:italic>quinquefasciatus<\/jats:italic> in order to understand their roles in the transmission of ZIKV in Guadalajara, Jalisco, Mexico. In blood feeding laboratry experiments, we found that <jats:italic>Ae<\/jats:italic>. <jats:italic>aegypti<\/jats:italic> mosquitoes showed to be a competent vector able to transmit ZIKV in this area. On the other hand, we found that F0 <jats:italic>Cx<\/jats:italic>. <jats:italic>quinquefasciatus<\/jats:italic> mosquitoes are refractory to ZIKV infection, dissemination and transmission.<\/jats:p>","DOI":"10.1038\/s41598-019-53117-1","type":"journal-article","created":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T11:02:12Z","timestamp":1574074932000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Vector competence of Aedes aegypti and Culex quinquefasciatus from the metropolitan area of Guadalajara, Jalisco, Mexico for Zika virus"],"prefix":"10.1038","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7256-947X","authenticated-orcid":false,"given":"Darwin","family":"Elizondo-Quiroga","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Ram\u00edrez-Medina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abel","family":"Guti\u00e9rrez-Ortega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armando","family":"Elizondo-Quiroga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Esteban","family":"Mu\u00f1oz-Medina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo","family":"S\u00e1nchez-Tejeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cassandra","family":"Gonz\u00e1lez-Acosta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabi\u00e1n","family":"Correa-Morales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,11,18]]},"reference":[{"key":"53117_CR1","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/0035-9203(52)90042-4","volume":"46","author":"GWA Dick","year":"1952","unstructured":"Dick, G. 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