{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T09:18:25Z","timestamp":1793092705673,"version":"4.5.0"},"reference-count":63,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2019,11,29]],"date-time":"2019-11-29T00:00:00Z","timestamp":1574985600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2019,11,29]],"date-time":"2019-11-29T00:00:00Z","timestamp":1574985600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100000002","name":"U.S. Department of Health & Human Services | National Institutes of Health","doi-asserted-by":"publisher","award":["1 R01 DC016315-01A1"],"award-info":[{"award-number":["1 R01 DC016315-01A1"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"U.S. Department of Health & Human Services | National Institutes of Health","doi-asserted-by":"publisher","award":["1 R01 DC016315-01A1"],"award-info":[{"award-number":["1 R01 DC016315-01A1"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"U.S. Department of Health & Human Services | National Institutes of Health","doi-asserted-by":"publisher","award":["1 R21 DC011841"],"award-info":[{"award-number":["1 R21 DC011841"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"U.S. Department of Health & Human Services | National Institutes of Health"},{"name":"U.S. Department of Health & Human Services | National Institutes of Health"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Spasmodic dysphonia (SD) is an incurable focal dystonia of the larynx that impairs speech and communication. Vibro-tactile stimulation (VTS) alters afferent proprioceptive input to sensorimotor cortex that controls speech. This proof-of-concept study examined the effect of laryngeal VTS on speech quality and cortical activity in 13\u00a0SD participants who vocalized the vowel \/a\/ while receiving VTS for 29\u2009minutes. In response to VTS, 9 participants (69%) exhibited a reduction of voice breaks and\/or a meaningful increase in<jats:italic>smoothed cepstral peak prominence<\/jats:italic>, an acoustic measure of voice\/speech quality. Symptom improvements persisted for 20\u2009minutes past VTS. Application of VTS induced a significant suppression of theta band power over the left somatosensory-motor cortex and a significant rise of gamma rhythm over right somatosensory-motor cortex. Such suppression of theta oscillations is observed in patients with cervical dystonia who apply effective sensory tricks, suggesting that VTS in SD may activate a similar neurophysiological mechanism. Results of this feasibility study indicate that laryngeal VTS modulates neuronal synchronization over sensorimotor cortex, which can induce short-term improvements in voice quality. The effects of long-term VTS and its optimal dosage for treating voice symptoms in SD are still unknown and require further systematic study.<\/jats:p>","DOI":"10.1038\/s41598-019-54396-4","type":"journal-article","created":{"date-parts":[[2019,11,29]],"date-time":"2019-11-29T11:03:10Z","timestamp":1575025390000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Laryngeal vibration as a non-invasive neuromodulation therapy for spasmodic dysphonia"],"prefix":"10.1038","volume":"9","author":[{"given":"Sanaz","family":"Khosravani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4097-9308","authenticated-orcid":false,"given":"Arash","family":"Mahnan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I-Ling","family":"Yeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua E.","family":"Aman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Watson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Goding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4422-5610","authenticated-orcid":false,"given":"J\u00fcrgen","family":"Konczak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,11,29]]},"reference":[{"key":"54396_CR1","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1159\/000059525","volume":"21","author":"E Castelon Konkiewitz","year":"2002","unstructured":"Castelon Konkiewitz, E. et al. Service-based survey of dystonia in Munich. Neuroepidemiology 21, 202\u2013206 (2002).","journal-title":"Neuroepidemiology"},{"key":"54396_CR2","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1523\/JNEUROSCI.2758-10.2011","volume":"31","author":"CL Ludlow","year":"2011","unstructured":"Ludlow, C. L. Spasmodic dysphonia: a laryngeal control disorder specific to speech. J Neurosci 31, 793\u2013393 (2011).","journal-title":"J Neurosci"},{"key":"54396_CR3","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004327.pub2","author":"C Watts","year":"2004","unstructured":"Watts, C., Whurr, R. & Nye, C. Botulinum toxin injections for the treatment of spasmodic dysphonia. Cochrance Database Sys Rev. https:\/\/doi.org\/10.1002\/14651858.CD004327.pub2 (2004).","journal-title":"Cochrance Database Sys Rev"},{"key":"54396_CR4","doi-asserted-by":"publisher","first-page":"14705","DOI":"10.1523\/JNEUROSCI.0407-13.2013","volume":"33","author":"K Simonyan","year":"2013","unstructured":"Simonyan, K., Berman, B. D., Herscovitch, P. & Hallett, M. Abnormal striatal dopaminergic neurotransmission during rest and task production in spasmodic dysphonia. J Neurosci 33, 14705\u201314714, https:\/\/doi.org\/10.1523\/JNEUROSCI.0407-13.2013 (2013).","journal-title":"J Neurosci"},{"key":"54396_CR5","doi-asserted-by":"publisher","first-page":"928","DOI":"10.1177\/000348949510401203","volume":"104","author":"CL Ludlow","year":"1995","unstructured":"Ludlow, C. L., Yamashita, T., Schulz, G. M. & Deleyiannis, F. W. B. Abnormalities in long latency responses to superior laryngeal nerve stimulation in adductor spasmodic dysphonia. Ann Otol Rhinol Laryngol 104, 928\u2013935, https:\/\/doi.org\/10.1177\/000348949510401203 (1995).","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"54396_CR6","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.neulet.2013.12.007","volume":"560","author":"S Samargia","year":"2014","unstructured":"Samargia, S., Schmidt, R. & Kimberley, T. J. Shortened cortical silent period in adductor spasmodic dysphonia: Evidence for widespread cortical excitability. Neurosci Lett 560, 12\u201315, https:\/\/doi.org\/10.1016\/j.neulet.2013.12.007 (2014).","journal-title":"Neurosci Lett"},{"key":"54396_CR7","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1093\/brain\/awm303","volume":"131","author":"K Simonyan","year":"2008","unstructured":"Simonyan, K. et al. Focal white matter changes in spasmodic dysphonia: a combined diffusion tensor imaging and neuropathological study. Brain 131, 447\u2013459, https:\/\/doi.org\/10.1093\/brain\/awm303 (2008).","journal-title":"Brain"},{"key":"54396_CR8","doi-asserted-by":"publisher","first-page":"2749","DOI":"10.1093\/cercor\/bhq023","volume":"20","author":"K Simonyan","year":"2010","unstructured":"Simonyan, K. & Ludlow, C. L. Abnormal activation of the primary somatosensory cortex in spasmodic dysphonia: an fMRI study. Cereb Cortex 20, 2749\u20132759, https:\/\/doi.org\/10.1093\/cercor\/bhq023 (2010).","journal-title":"Cereb Cortex"},{"key":"54396_CR9","doi-asserted-by":"publisher","first-page":"2312","DOI":"10.1093\/brain\/awg230","volume":"126","author":"M Maschke","year":"2003","unstructured":"Maschke, M., Gomez, C. M., Tuite, P. J. & Konczak, J. Dysfunction of the basal ganglia, but not the cerebellum, impairs kinaesthesia. Brain 126, 2312\u20132322, https:\/\/doi.org\/10.1093\/brain\/awg230 (2003).","journal-title":"Brain"},{"key":"54396_CR10","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1002\/mds.20799","volume":"21","author":"N Putzki","year":"2006","unstructured":"Putzki, N. et al. Kinesthesia is impaired in focal dystonia. Mov Dis 21, 754\u2013760, https:\/\/doi.org\/10.1002\/mds.20799 (2006).","journal-title":"Mov Dis"},{"key":"54396_CR11","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1136\/jnnp-2013-307316","volume":"85","author":"N Patel","year":"2014","unstructured":"Patel, N., Hanfelt, J., Marsh, L. & Jankovic, J. Alleviating manoeuvres (sensory tricks) in cervical dystonia. J Neurol Neurosurg Psychiatry 85, 882\u2013884, https:\/\/doi.org\/10.1136\/jnnp-2013-307316 (2014).","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"54396_CR12","doi-asserted-by":"publisher","first-page":"777.e717","DOI":"10.1016\/j.jvoice.2014.12.010","volume":"29","author":"J Konczak","year":"2015","unstructured":"Konczak, J., Aman, J. E. & Chen, Y.-W. Li, K.-y. & Watson, P. J. Impaired limb proprioception in adults with spasmodic dysphonia. J Voice 29, 777.e717\u2013777.e723, https:\/\/doi.org\/10.1016\/j.jvoice.2014.12.010 (2015).","journal-title":"J Voice"},{"key":"54396_CR13","doi-asserted-by":"publisher","first-page":"356","DOI":"10.1002\/mds.25305","volume":"28","author":"G K\u00e4gi","year":"2013","unstructured":"K\u00e4gi, G. et al. Sensory tricks in primary cervical dystonia depend on visuotactile temporal discrimination. Mov Dis 28, 356\u2013361, https:\/\/doi.org\/10.1002\/mds.25305 (2013).","journal-title":"Mov Dis"},{"key":"54396_CR14","doi-asserted-by":"publisher","first-page":"1580","DOI":"10.1007\/s00415-011-6380-7","volume":"259","author":"A Poisson","year":"2012","unstructured":"Poisson, A. et al. History of the \u2018geste antagoniste\u2019 sign in cervical dystonia. J Neurol 259, 1580\u20131584, https:\/\/doi.org\/10.1007\/s00415-011-6380-7 (2012).","journal-title":"J Neurol"},{"key":"54396_CR15","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1136\/jnnp.69.5.658","volume":"69","author":"H Karnath","year":"2000","unstructured":"Karnath, H., Konczak, J. & Dichgans, J. Effect of prolonged neck muscle vibration on lateral head tilt in severe spasmodic torticollis. J Neurol Neurosurg Psychiatry 69, 658\u2013660, https:\/\/doi.org\/10.1136\/jnnp.69.5.658 (2000).","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"54396_CR16","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1152\/jn.1963.26.1.177","volume":"26","author":"R Bianconi","year":"1963","unstructured":"Bianconi, R. & Van Der Meulen, J. P. The response to vibraion of the end organs of mammalian muscle spindels. J Neurophysiol 26, 177\u2013190, https:\/\/doi.org\/10.1152\/jn.1963.26.1.177 (1963).","journal-title":"J Neurophysiol"},{"key":"54396_CR17","doi-asserted-by":"publisher","first-page":"31P","DOI":"10.1113\/jphysiol.1967.sp008250","volume":"191","author":"MC Brown","year":"1967","unstructured":"Brown, M. C. & Matthews, E. I. PB. The use of vibration as a selective repetitive stimulus for Ia afferent fibres. J Physiol 191, 31P\u201332P (1967).","journal-title":"J Physiol"},{"key":"54396_CR18","doi-asserted-by":"publisher","first-page":"1675","DOI":"10.1152\/jn.1995.74.4.1675","volume":"74","author":"P Cordo","year":"1995","unstructured":"Cordo, P., Gurfinkel, V. S., Bevan, L. & Kerr, G. K. Proprioceptive consequences of tendon vibration during movement. J Neurophysiol 74, 1675\u20131688, https:\/\/doi.org\/10.1152\/jn.1995.74.4.1675 (1995).","journal-title":"J Neurophysiol"},{"key":"54396_CR19","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1007\/s00221-005-0034-x","volume":"167","author":"PJ Cordo","year":"2005","unstructured":"Cordo, P. J., Gurfinkel, V. S., Brumagne, S. & Flores-Vieira, C. Effect of slow, small movement on the vibration-evoked kinesthetic illusion. Exp Brain Res 167, 324\u2013334, https:\/\/doi.org\/10.1007\/s00221-005-0034-x (2005).","journal-title":"Exp Brain Res"},{"key":"54396_CR20","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1044\/jshr.1403.513","volume":"14","author":"RJ Baken","year":"1971","unstructured":"Baken, R. J. & Noback, C. R. Neuromuscular spindles in intrinsic muscles of a human larynx. J Speech Lang Hearing Res 14, 513\u2013518, https:\/\/doi.org\/10.1044\/jshr.1403.513 (1971).","journal-title":"J Speech Lang Hearing Res"},{"key":"54396_CR21","first-page":"124","volume":"15","author":"M Grim","year":"1967","unstructured":"Grim, M. Muscle spindles in the posterior cricoarytenoid muscle of the human larynx. Folia Morphologia (Praha) 15, 124\u2013131 (1967).","journal-title":"Folia Morphologia (Praha)"},{"key":"54396_CR22","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1007\/BF00455315","volume":"244","author":"M Hirayama","year":"1987","unstructured":"Hirayama, M., Matsui, T., Tachibana, M., Ibata, Y. & Mizukoshi, O. An electron microscopic study of the muscle spindle in the arytenoid muscle of the human larynx. Eur Arch Otorhinolarynigol 244, 249\u2013252 (1987).","journal-title":"Eur Arch Otorhinolarynigol"},{"key":"54396_CR23","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1007\/BF00384340","volume":"48","author":"K Paulsen","year":"1958","unstructured":"Paulsen, K. Occurrence & number of muscle spindles in internal laryngeal muscles of humans (m. cricoarytenoideus & m. cricothyreoideus)]. Z Zellforsch Mikro Anat 48, 349\u2013355 (1958).","journal-title":"Z Zellforsch Mikro Anat"},{"key":"54396_CR24","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1177\/000348940411300203","volume":"113","author":"CM Tellis","year":"2004","unstructured":"Tellis, C. M., Rosen, C., Thekdi, A. & Sciote, J. J. Anatomy and fiber type composition of human interarytenoid muscle. Ann Otol Rhinol Laryngol 113, 97\u2013107 (2004).","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"54396_CR25","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1016\/S0892-1997(03)00013-4","volume":"17","author":"CA Brandon","year":"2003","unstructured":"Brandon, C. A. et al. Staining of human thyroarytenoid muscle with myosin antibodies reveals some unique extrafusal fibers, but no muscle spindles. J Voice 17, 245\u2013254 (2003).","journal-title":"J Voice"},{"key":"54396_CR26","doi-asserted-by":"publisher","first-page":"922","DOI":"10.1152\/japplphysiol.00402.2004","volume":"99","author":"TMJ Loucks","year":"2005","unstructured":"Loucks, T. M. J., Poletto, C. J., Saxon, K. G. & Ludlow, C. L. Laryngeal muscle responses to mechanical displacement of the thyroid cartilage in humans. J App Physiol 99, 922\u2013930, https:\/\/doi.org\/10.1152\/japplphysiol.00402.2004 (2005).","journal-title":"J App Physiol"},{"key":"54396_CR27","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1113\/jphysiol.1987.sp016625","volume":"388","author":"PJ Davis","year":"1987","unstructured":"Davis, P. J. & Nail, B. S. Quantitative analysis of laryngeal mechanosensitivity in the cat and rabbit. J Physiol 388, 467\u2013485 (1987).","journal-title":"J Physiol"},{"key":"54396_CR28","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1679\/aohc.45.145","volume":"45","author":"T Nagai","year":"1982","unstructured":"Nagai, T. Encapsulated sensory corpuscle in the mucosa of human vocal cord: An electron microscope study. Arch Histol Jap 45, 145\u2013153, https:\/\/doi.org\/10.1679\/aohc.45.145 (1982).","journal-title":"Arch Histol Jap"},{"key":"54396_CR29","doi-asserted-by":"publisher","first-page":"1622","DOI":"10.1152\/japplphysiol.00417.2002","volume":"93","author":"RD Andreatta","year":"2002","unstructured":"Andreatta, R. D., Mann, E. A., Poletto, C. J. & Ludlow, C. L. Mucosal afferents mediate laryngeal adductor responses in the cat. J Appl Physiol (1985) 93, 1622\u20131629, https:\/\/doi.org\/10.1152\/japplphysiol.00417.2002 (2002).","journal-title":"J Appl Physiol (1985)"},{"key":"54396_CR30","unstructured":"Woodson, G. E. In Laryngeal Evaluation: Indirect Laryngoscopy to High-Speed Digital Imaging (ed Katherine A. Kendall; Rebecca J. Leonard) Ch. 25, (Thieme, 2010)."},{"key":"54396_CR31","doi-asserted-by":"publisher","first-page":"2619","DOI":"10.1121\/1.3224706","volume":"126","author":"Y Maryn","year":"2009","unstructured":"Maryn, Y., Roy, N., De Bodt, M., Van Cauwenberge, P. & Corthals, P. Acoustic measurement of overall voice quality: a meta-analysis. J Acoust Soc Am 126, 2619\u20132634, https:\/\/doi.org\/10.1121\/1.3224706 (2009).","journal-title":"J Acoust Soc Am"},{"key":"54396_CR32","doi-asserted-by":"publisher","first-page":"S49","DOI":"10.1002\/mds.10142","volume":"17","author":"JL Vitek","year":"2002","unstructured":"Vitek, J. L. Pathophysiology of dystonia: A neuronal model. Mov Dis 17, S49\u2013S62, https:\/\/doi.org\/10.1002\/mds.10142 (2002).","journal-title":"Mov Dis"},{"key":"54396_CR33","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1111\/j.1749-6632.2012.06692.x","volume":"1265","author":"CM Hendrix","year":"2012","unstructured":"Hendrix, C. M. & Vitek, J. L. Toward a network model of dystonia. Ann New York Acad Sci 1265, 46\u201355, https:\/\/doi.org\/10.1111\/j.1749-6632.2012.06692.x (2012).","journal-title":"Ann New York Acad Sci"},{"key":"54396_CR34","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1016\/j.nurt.2008.01.010","volume":"5","author":"MD Johnson","year":"2008","unstructured":"Johnson, M. D., Miocinovic, S., McIntyre, C. C. & Vitek, J. L. Mechanisms and targets of deep brain stimulation in movement disorders. Neurotherapeutics 5, 294\u2013308, https:\/\/doi.org\/10.1016\/j.nurt.2008.01.010 (2008).","journal-title":"Neurotherapeutics"},{"key":"54396_CR35","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1097\/WNP.0000000000000186","volume":"32","author":"CL Ludlow","year":"2015","unstructured":"Ludlow, C. L. Central nervous system control of voice and swallowing. J Clin Neurophysiol 32, 294\u2013303, https:\/\/doi.org\/10.1097\/WNP.0000000000000186 (2015).","journal-title":"J Clin Neurophysiol"},{"key":"54396_CR36","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1016\/j.neuron.2004.08.035","volume":"43","author":"JD Berke","year":"2004","unstructured":"Berke, J. D., Okatan, M., Skurski, J. & Eichenbaum, H. B. Oscillatory entrainment of striatal neurons in freely moving rats. Neuron 43, 883\u2013896, https:\/\/doi.org\/10.1016\/j.neuron.2004.08.035 (2004).","journal-title":"Neuron"},{"key":"54396_CR37","doi-asserted-by":"publisher","first-page":"RC131","DOI":"10.1523\/JNEUROSCI.21-04-j0003.2001","volume":"21","author":"Y Goto","year":"2001","unstructured":"Goto, Y. & O\u2019Donnell, P. Synchronous activity in the hippocampus and nucleus accumbens in vivo. J Neurosci 21, RC131\u2013RC131, https:\/\/doi.org\/10.1523\/JNEUROSCI.21-04-j0003.2001 (2001).","journal-title":"J Neurosci"},{"key":"54396_CR38","doi-asserted-by":"publisher","first-page":"346","DOI":"10.1002\/mds.10038","volume":"17","author":"X Liu","year":"2002","unstructured":"Liu, X. et al. Involvement of the medial pallidum in focal myoclonic dystonia: A clinical and neurophysiological case study. Mov Dis 17, 346\u2013353 (2002).","journal-title":"Mov Dis"},{"key":"54396_CR39","doi-asserted-by":"publisher","first-page":"1562","DOI":"10.1093\/brain\/awn083","volume":"131","author":"X Liu","year":"2008","unstructured":"Liu, X. et al. The sensory and motor representation of synchronized oscillations in the globus pallidus in patients with primary dystonia. Brain 131, 1562\u20131573, https:\/\/doi.org\/10.1093\/brain\/awn083 (2008).","journal-title":"Brain"},{"key":"54396_CR40","doi-asserted-by":"publisher","first-page":"912","DOI":"10.1002\/ana.25095","volume":"82","author":"W-J Neumann","year":"2017","unstructured":"Neumann, W.-J. et al. A localized pallidal physiomarker in cervical dystonia. Ann. Neurol. 82, 912\u2013924, https:\/\/doi.org\/10.1002\/ana.25095 (2017).","journal-title":"Ann. Neurol."},{"key":"54396_CR41","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1016\/j.expneurol.2007.01.010","volume":"204","author":"JK Tang","year":"2007","unstructured":"Tang, J. K. et al. Changes in cortical and pallidal oscillatory activity during the execution of a sensory trick in patients with cervical dystonia. Exp Neurol 204, 845\u2013848 (2007).","journal-title":"Exp Neurol"},{"key":"54396_CR42","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1007\/s40473-018-0151-z","volume":"5","author":"M Nowak","year":"2018","unstructured":"Nowak, M., Zich, C. & Stagg, C. J. Motor cortical gamma oscillations: what have we learnt and where are we headed? Curr Behav Neurosci Rep 5, 136\u2013142, https:\/\/doi.org\/10.1007\/s40473-018-0151-z (2018).","journal-title":"Curr Behav Neurosci Rep"},{"key":"54396_CR43","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1523\/JNEUROSCI.5228-04.2006","volume":"26","author":"M Bauer","year":"2006","unstructured":"Bauer, M., Oostenveld, R., Peeters, M. & Fries, P. Tactile spatial attention enhances gamma-band activity in somatosensory cortex and reduces low-frequency activity in parieto-occipital areas. J Neurosci 26, 490, https:\/\/doi.org\/10.1523\/JNEUROSCI.5228-04.2006 (2006).","journal-title":"J Neurosci"},{"key":"54396_CR44","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1038\/35094565","volume":"2","author":"AK Engel","year":"2001","unstructured":"Engel, A. K., Fries, P. & Singer, W. Dynamic predictions: oscillations and synchrony in top\u2013down processing. Nat Rev Neurosci 2, 704\u2013716, https:\/\/doi.org\/10.1038\/35094565 (2001).","journal-title":"Nat Rev Neurosci"},{"key":"54396_CR45","doi-asserted-by":"publisher","first-page":"RC211","DOI":"10.1523\/JNEUROSCI.22-04-j0003.2002","volume":"22","author":"S Palva","year":"2002","unstructured":"Palva, S. et al. Distinct gamma-band evoked responses to speech and non-speech sounds in humans. J Neurosci 22, RC211\u2013RC211, https:\/\/doi.org\/10.1523\/JNEUROSCI.22-04-j0003.2002 (2002).","journal-title":"J Neurosci"},{"key":"54396_CR46","doi-asserted-by":"publisher","first-page":"4430","DOI":"10.1073\/pnas.0913697107","volume":"107","author":"KJ Miller","year":"2010","unstructured":"Miller, K. J. et al. Cortical activity during motor execution, motor imagery, and imagery-based online feedback. Proc Natl Acad Sci USA 107, 4430\u20134435, https:\/\/doi.org\/10.1073\/pnas.0913697107 (2010).","journal-title":"Proc Natl Acad Sci USA"},{"key":"54396_CR47","doi-asserted-by":"publisher","first-page":"2873","DOI":"10.1152\/jn.00607.2010","volume":"104","author":"SD Muthukumaraswamy","year":"2010","unstructured":"Muthukumaraswamy, S. D. Functional properties of human primary motor cortex gamma oscillations. J Neurophysiol 104, 2873\u20132885, https:\/\/doi.org\/10.1152\/jn.00607.2010 (2010).","journal-title":"J Neurophysiol"},{"key":"54396_CR48","doi-asserted-by":"publisher","first-page":"1008","DOI":"10.1523\/JNEUROSCI.3860-11.2012","volume":"32","author":"C Br\u00fccke","year":"2012","unstructured":"Br\u00fccke, C. et al. Scaling of movement is related to pallidal \u03b3 oscillations in patients with dystonia. J Neurosci 32, 1008, https:\/\/doi.org\/10.1523\/JNEUROSCI.3860-11.2012 (2012).","journal-title":"J Neurosci"},{"key":"54396_CR49","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1016\/j.jvoice.2013.04.002","volume":"27","author":"EA Peterson","year":"2013","unstructured":"Peterson, E. A. et al. Toward validation of the cepstral spectral index of dysphonia (CSID) as an objective treatment outcomes measure. J Voice 27, 401\u2013410, https:\/\/doi.org\/10.1016\/j.jvoice.2013.04.002 (2013).","journal-title":"J Voice"},{"key":"54396_CR50","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1044\/1058-0360(2008\/08-0017)","volume":"18","author":"GB Kempster","year":"2009","unstructured":"Kempster, G. B., Gerratt, B. R., Abbott, K. V., Barkmeier-Kraemer, J. & Hillman, R. E. Consensus auditory-perceptual evaluation of voice: development of a standardized clinical protocol. Am J Speech Lang Pathol 18, 124\u2013132, https:\/\/doi.org\/10.1044\/1058-0360(2008\/08-0017) (2009).","journal-title":"Am J Speech Lang Pathol"},{"key":"54396_CR51","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1001\/jamaoto.2018.0644","volume":"144","author":"CL Ludlow","year":"2018","unstructured":"Ludlow, C. L. et al. Consensus-Based Attributes for Identifying Patients With Spasmodic Dysphonia and Other Voice Disorders. JAMA. Otolaryngol Head Neck Surg 144, 657\u2013665, https:\/\/doi.org\/10.1001\/jamaoto.2018.0644 (2018).","journal-title":"Otolaryngol Head Neck Surg"},{"key":"54396_CR52","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.bspc.2014.07.001","volume":"14","author":"R Fraile","year":"2014","unstructured":"Fraile, R. & Godino-Llorente, J. I. Cepstral peak prominence: a comprehensive analysis. Biomed Signal Process Control 14, 42\u201354, https:\/\/doi.org\/10.1016\/j.bspc.2014.07.001 (2014).","journal-title":"Biomed Signal Process Control"},{"key":"54396_CR53","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1044\/jshr.3902.311","volume":"39","author":"J Hillenbrand","year":"1996","unstructured":"Hillenbrand, J. & Houde, R. A. Acoustic correlates of breathy vocal quality: dysphonic voices and continuous speech. J Speech Lang Hearing Res 39, 311\u2013321, https:\/\/doi.org\/10.1044\/jshr.3902.311 (1996).","journal-title":"J Speech Lang Hearing Res"},{"key":"54396_CR54","first-page":"341","volume":"5","author":"P Boersma","year":"2001","unstructured":"Boersma, P. & van Heuven, V. Speak and unspeak with PRAAT. Glot International 5, 341\u2013347 (2001).","journal-title":"Glot International"},{"key":"54396_CR55","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.jneumeth.2003.10.009","volume":"134","author":"A Delorme","year":"2004","unstructured":"Delorme, A. & Makeig, S. EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis. J Neurosci Method 134, 9\u201321, https:\/\/doi.org\/10.1016\/j.jneumeth.2003.10.009 (2004).","journal-title":"J Neurosci Method"},{"key":"54396_CR56","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.jneumeth.2015.02.025","volume":"250","author":"M Chaumon","year":"2015","unstructured":"Chaumon, M., Bishop, D. V. M. & Busch, N. A. A practical guide to the selection of independent components of the electroencephalogram for artifact correction. J Neurosci Method 250, 47\u201363, https:\/\/doi.org\/10.1016\/j.jneumeth.2015.02.025 (2015).","journal-title":"J Neurosci Method"},{"key":"54396_CR57","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/0013-4694(93)90110-H","volume":"86","author":"S Makeig","year":"1993","unstructured":"Makeig, S. Auditory event-related dynamics of the EEG spectrum and effects of exposure to tones. Electroencephalog. Clin Neurophysiol 86, 283\u2013293, https:\/\/doi.org\/10.1016\/0013-4694(93)90110-H (1993).","journal-title":"Clin Neurophysiol"},{"key":"54396_CR58","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1044\/1092-4388(2006\/033)","volume":"49","author":"JN Caviness","year":"2006","unstructured":"Caviness, J. N., Liss, J. M., Adler, C. & Evidente, V. Analysis of high-frequency electroencephalographic-electromyographic coherence elicited by speech and oral nonspeech tasks in parkinson\u2019s disease. J Speech Lang Hearing Res 49, 424\u2013438, https:\/\/doi.org\/10.1044\/1092-4388(2006\/033) (2006).","journal-title":"J Speech Lang Hearing Res"},{"key":"54396_CR59","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1002\/lary.26655","volume":"128","author":"N Mor","year":"2018","unstructured":"Mor, N., Simonyan, K. & Blitzer, A. Central voice production and pathophysiology of spasmodic dysphonia. Laryngoscope 128, 177\u2013183, https:\/\/doi.org\/10.1002\/lary.26655 (2018).","journal-title":"Laryngoscope"},{"key":"54396_CR60","doi-asserted-by":"crossref","unstructured":"Pfurtscheller, G. & Andrew, C. Event-related changes of band power and coherence: methodology and interpretation. J Clin Neurophysiol 16 (1999).","DOI":"10.1097\/00004691-199911000-00003"},{"key":"54396_CR61","doi-asserted-by":"publisher","first-page":"336","DOI":"10.5935\/1808-8694.20130059","volume":"79","author":"KF Alvarenga","year":"2013","unstructured":"Alvarenga, K. F. et al. The influence of speech stimuli contrast in cortical auditory evoked potentials. Brazil J Otorhinolaryngol 79, 336\u2013341 (2013).","journal-title":"Brazil J Otorhinolaryngol"},{"key":"54396_CR62","doi-asserted-by":"publisher","first-page":"393","DOI":"10.3758\/BF03329370","volume":"10","author":"JL Santee","year":"1977","unstructured":"Santee, J. L. & Kohfeld, D. L. Auditory reaction time as a function of stimulus intensity, frequency, and rise time. Bull Psychonom Soc 10, 393\u2013396, https:\/\/doi.org\/10.3758\/BF03329370 (1977).","journal-title":"Bull Psychonom Soc"},{"key":"54396_CR63","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","volume":"57","author":"Y Benjamini","year":"1995","unstructured":"Benjamini, Y. & Hochberg, Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Royal Stat Soc Series B 57, 289\u2013300 (1995).","journal-title":"J Royal Stat Soc Series B"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-019-54396-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-019-54396-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-019-54396-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,27]],"date-time":"2024-07-27T22:25:23Z","timestamp":1722119123000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-019-54396-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,29]]},"references-count":63,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,12]]}},"alternative-id":["54396"],"URL":"https:\/\/doi.org\/10.1038\/s41598-019-54396-4","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,29]]},"assertion":[{"value":"1 August 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 November 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 November 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"17955"}}