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Compound nevus was the most common type of conjunctival pigmented lesions (67.1%), followed by conjunctival melanocytic intraepithelial neoplasia (primary acquired melanosis)(11.8%), subepithelial nevus (8.2%), and malignant melanoma (MM)(7.1%). Patients with compound nevus were younger than those with non-compound nevus (22.1\u2009\u00b1\u200917.0 vs 39.9\u2009\u00b1\u200918.8 years, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), while patients with MM were older than those without melanoma (55.7\u2009\u00b1\u200918.2 vs 25.8\u2009\u00b1\u200918.0 years, p\u2009=\u20090.001). The lesion in compound nevus tended to be more frequently located on the temporal conjunctiva than that in the non-compound nevus group (54.4% vs 32.1%, <jats:italic>p<\/jats:italic>\u2009=\u20090.053), and feeder vessels were associated with most of compound nevus (98.2% vs 78.6% of non-compound nevus, <jats:italic>p<\/jats:italic>\u2009=\u20090.005). The lesion in MM was larger, involved multiple quadrants, and had extrabulbar location than lesions without melanoma (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, and <jats:italic>p<\/jats:italic>\u2009=\u20090.002, respectively). Together, the results would help clinicians to distinguish benign conjunctival pigmentations from malignant counterparts in clinical practice without biopsy.<\/jats:p>","DOI":"10.1038\/s41598-019-54786-8","type":"journal-article","created":{"date-parts":[[2019,12,3]],"date-time":"2019-12-03T11:04:18Z","timestamp":1575371058000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Conjunctival pigmented lesion: Clinicopathological analysis of 85 cases in Korean population"],"prefix":"10.1038","volume":"9","author":[{"given":"Yun Jeong","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheol","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7850-6894","authenticated-orcid":false,"given":"Mee Kum","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4217-7907","authenticated-orcid":false,"given":"Sang In","family":"Khwarg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7899-5314","authenticated-orcid":false,"given":"Joo Youn","family":"Oh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,12,3]]},"reference":[{"key":"54786_CR1","doi-asserted-by":"publisher","first-page":"1747","DOI":"10.1016\/j.ophtha.2004.02.013","volume":"111","author":"CL Shields","year":"2004","unstructured":"Shields, C. 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