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Twenty-nine patients with positive serology for <jats:italic>Trypanosoma cruzi<\/jats:italic> and dysphagia (Chagas\u2019 disease group) and 29 individuals matched by sex and age (control group) participated in the study. Surface electromyography of the suprahyoid musculature and videofluoroscopy during swallowing of paste and liquid consistencies were performed. Canonical correlation analysis of the MANOVA test results showed that the Chagas\u2019 disease group had lower electromyographic activity when compared with controls. Overlapping circles of radiological findings were found for megaesophagus. The Spearman test showed a positive correlation between the electromyographic activity in the maximum voluntary isometric contraction and the time of pharyngeal transit for both liquid (<jats:italic>p<\/jats:italic>\u2009=\u20090.014) and paste (<jats:italic>p<\/jats:italic>\u2009=\u20090.047). The logistic regression test showed no association between electromyographic activity of the suprahyoid muscles and esophageal manometry results (p\u2009&gt;\u20090.05). In conclusion, individuals with chagasic megaesophagus have reduced electromyographic activity of the suprahyoid muscles during swallowing, in addition to a greater recruitment of the suprahyoid musculature with increased pharyngeal transit time.<\/jats:p>","DOI":"10.1038\/s41598-019-55402-5","type":"journal-article","created":{"date-parts":[[2019,12,11]],"date-time":"2019-12-11T12:44:58Z","timestamp":1576068298000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Suprahyoid Muscle Activity in Patients with Chagasic Megaesophagus"],"prefix":"10.1038","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6183-2204","authenticated-orcid":false,"given":"Aretuza Zaupa Gasparim","family":"El Gharib","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gi\u00e9dre","family":"Berretin-Felix","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto Oliveira","family":"Dantas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6337-6628","authenticated-orcid":false,"given":"Diogo Francisco","family":"Rossoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max Jean","family":"de Ornelas Toledo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,12,11]]},"reference":[{"key":"55402_CR1","unstructured":"WHO. 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