{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:21:48Z","timestamp":1791764508235,"version":"4.3.4"},"reference-count":72,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2020,3,27]],"date-time":"2020-03-27T00:00:00Z","timestamp":1585267200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,3,27]],"date-time":"2020-03-27T00:00:00Z","timestamp":1585267200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The posterior parietal cortex (PPC) and frontal motor areas comprise a cortical network supporting goal-directed behaviour, with functions including sensorimotor transformations and decision making. In primates, this network links performed and observed actions via mirror neurons, which fire both when individuals perform an action and when they observe the same action performed by a conspecific. Mirror neurons are believed to be important for social learning, but it is not known whether mirror-like neurons occur in similar networks in other social species, such as rodents, or if they can be measured in such models using paradigms where observers passively view a demonstrator. Therefore, we imaged Ca\n                    <jats:sup>2+<\/jats:sup>\n                    responses in PPC and secondary motor cortex (M2) while mice performed and observed pellet-reaching and wheel-running tasks, and found that cell populations in both areas robustly encoded several naturalistic behaviours. However, neural responses to the same set of observed actions were absent, although we verified that observer mice were attentive to performers and that PPC neurons responded reliably to visual cues. Statistical modelling also indicated that executed actions outperformed observed actions in predicting neural responses. These results raise the possibility that sensorimotor action recognition in rodents could take place outside of the parieto-frontal circuit, and underscore that detecting socially-driven neural coding depends critically on the species and behavioural paradigm used.\n                  <\/jats:p>","DOI":"10.1038\/s41598-020-62089-6","type":"journal-article","created":{"date-parts":[[2020,3,27]],"date-time":"2020-03-27T07:03:11Z","timestamp":1585292591000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Action representation in the mouse parieto-frontal network"],"prefix":"10.1038","volume":"10","author":[{"given":"Tuce","family":"Tombaz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin A.","family":"Dunn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karoline","family":"Hovde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan John","family":"Cubero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bartul","family":"Mimica","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pranav","family":"Mamidanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasser","family":"Roudi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2642-8737","authenticated-orcid":false,"given":"Jonathan R.","family":"Whitlock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,3,27]]},"reference":[{"key":"62089_CR1","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1641\/0006-3568(2005)055[0489:SLIAES]2.0.CO;2","volume":"55","author":"BG Galef Jr.","year":"2005","unstructured":"Galef, B. G. Jr. & Laland, K. N. Social Learning in Animals: Empirical Studies and Theoretical Models. BioScience 55, 489\u2013499, https:\/\/doi.org\/10.1641\/0006-3568(2005)055[0489:SLIAES]2.0.CO;2 (2005).","journal-title":"BioScience"},{"key":"62089_CR2","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1007\/BF00230027","volume":"91","author":"G di Pellegrino","year":"1992","unstructured":"di Pellegrino, G., Fadiga, L., Fogassi, L., Gallese, V. & Rizzolatti, G. Understanding motor events: a neurophysiological study. Exp Brain Res. 91, 176\u2013180 (1992).","journal-title":"Exp Brain Res."},{"issue":"Pt 2","key":"62089_CR3","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1093\/brain\/119.2.593","volume":"119","author":"V Gallese","year":"1996","unstructured":"Gallese, V., Fadiga, L., Fogassi, L. & Rizzolatti, G. Action recognition in the premotor cortex. Brain 119(Pt 2), 593\u2013609 (1996).","journal-title":"Brain"},{"key":"62089_CR4","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1126\/science.1106138","volume":"308","author":"L Fogassi","year":"2005","unstructured":"Fogassi, L. et al. Parietal lobe: from action organization to intention understanding. Science 308, 662\u2013667, https:\/\/doi.org\/10.1126\/science.1106138 (2005).","journal-title":"Science"},{"key":"62089_CR5","doi-asserted-by":"publisher","first-page":"750","DOI":"10.1016\/j.cub.2010.02.045","volume":"20","author":"R Mukamel","year":"2010","unstructured":"Mukamel, R., Ekstrom, A. D., Kaplan, J., Iacoboni, M. & Fried, I. Single-neuron responses in humans during execution and observation of actions. Curr Biol 20, 750\u2013756, https:\/\/doi.org\/10.1016\/j.cub.2010.02.045 (2010).","journal-title":"Curr Biol"},{"key":"62089_CR6","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1038\/nature06492","volume":"451","author":"JF Prather","year":"2008","unstructured":"Prather, J. F., Peters, S., Nowicki, S. & Mooney, R. Precise auditory-vocal mirroring in neurons for learned vocal communication. Nature 451, 305\u2013310, https:\/\/doi.org\/10.1038\/nature06492 (2008).","journal-title":"Nature"},{"key":"62089_CR7","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1146\/annurev.neuro.27.070203.144230","volume":"27","author":"G Rizzolatti","year":"2004","unstructured":"Rizzolatti, G. & Craighero, L. The mirror-neuron system. Ann Rev Neurosci 27, 169\u2013192, https:\/\/doi.org\/10.1146\/annurev.neuro.27.070203.144230 (2004).","journal-title":"Ann Rev Neurosci"},{"key":"62089_CR8","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1146\/annurev.psych.60.110707.163604","volume":"60","author":"M Iacoboni","year":"2009","unstructured":"Iacoboni, M. Imitation, empathy, and mirror neurons. Annu Rev Psychol 60, 653\u2013670, https:\/\/doi.org\/10.1146\/annurev.psych.60.110707.163604 (2009).","journal-title":"Annu Rev Psychol"},{"key":"62089_CR9","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1162\/jocn.2009.21189","volume":"21","author":"G Hickok","year":"2009","unstructured":"Hickok, G. Eight problems for the mirror neuron theory of action understanding in monkeys and humans. J Cogn Neurosci 21, 1229\u20131243, https:\/\/doi.org\/10.1162\/jocn.2009.21189 (2009).","journal-title":"J Cogn Neurosci"},{"key":"62089_CR10","doi-asserted-by":"publisher","first-page":"37","DOI":"10.3758\/BF03331765","volume":"24","author":"JD Russo","year":"1971","unstructured":"Russo, J. D. Observational learning in hooded rats. Psychonomic Science 24, 37\u201338 (1971).","journal-title":"Psychonomic Science"},{"key":"62089_CR11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.46867\/C4KW2H","volume":"5","author":"O Zohar","year":"1991","unstructured":"Zohar, O. & Terkel, J. Acquisition of pine cone stripping behavior in black rats (rattus rattus). International Journal of Comparative Psychology 5, 1\u20136 (1991).","journal-title":"International Journal of Comparative Psychology"},{"key":"62089_CR12","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.brainresprot.2003.08.001","volume":"12","author":"MG Leggio","year":"2003","unstructured":"Leggio, M. G. et al. A new paradigm to analyze observational learning in rats. Brain Res Brain Res Protoc 12, 83\u201390, https:\/\/doi.org\/10.1016\/j.brainresprot.2003.08.001 (2003).","journal-title":"Brain Res Brain Res Protoc"},{"key":"62089_CR13","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1037\/0735-7044.115.3.661","volume":"115","author":"M Kavaliers","year":"2001","unstructured":"Kavaliers, M., Choleris, E. & Colwell, D. D. Learning from others to cope with biting flies: social learning of fear-induced conditioned analgesia and active avoidance. Behav Neurosci 115, 661\u2013674 (2001).","journal-title":"Behav Neurosci"},{"key":"62089_CR14","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.bbr.2006.07.014","volume":"174","author":"P Carlier","year":"2006","unstructured":"Carlier, P. & Jamon, M. Observational learning in C57BL\/6j mice. Behavioural Brain Research 174, 125\u2013131, https:\/\/doi.org\/10.1016\/j.bbr.2006.07.014 (2006).","journal-title":"Behavioural Brain Research"},{"key":"62089_CR15","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1101\/lm.024760.111","volume":"19","author":"MT Jurado-Parras","year":"2012","unstructured":"Jurado-Parras, M. T., Gruart, A. & Delgado-Garcia, J. M. Observational learning in mice can be prevented by medial prefrontal cortex stimulation and enhanced by nucleus accumbens stimulation. Learn Mem 19, 99\u2013106, https:\/\/doi.org\/10.1101\/lm.024760.111 (2012).","journal-title":"Learn Mem"},{"key":"62089_CR16","doi-asserted-by":"publisher","first-page":"1967","DOI":"10.1126\/science.1128322","volume":"312","author":"DJ Langford","year":"2006","unstructured":"Langford, D. J. et al. Social modulation of pain as evidence for empathy in mice. Science 312, 1967\u20131970, https:\/\/doi.org\/10.1126\/science.1128322 (2006).","journal-title":"Science"},{"key":"62089_CR17","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-05894-y","volume":"9","author":"T Sakaguchi","year":"2018","unstructured":"Sakaguchi, T., Iwasaki, S., Okada, M., Okamoto, K. & Ikegaya, Y. Ethanol facilitates socially evoked memory recall in mice by recruiting pain-sensitive anterior cingulate cortical neurons. Nat Commun 9, 3526, https:\/\/doi.org\/10.1038\/s41467-018-05894-y (2018).","journal-title":"Nat Commun"},{"key":"62089_CR18","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1038\/nn.2504","volume":"13","author":"D Jeon","year":"2010","unstructured":"Jeon, D. et al. Observational fear learning involves affective pain system and Cav1.2 Ca2+ channels in ACC. Nature Neuroscience 13, 482\u2013488, https:\/\/doi.org\/10.1038\/nn.2504 (2010).","journal-title":"Nature Neuroscience"},{"key":"62089_CR19","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.1016\/j.cell.2018.04.004","volume":"173","author":"SA Allsop","year":"2018","unstructured":"Allsop, S. A. et al. Corticoamygdala Transfer of Socially Derived Information Gates Observational Learning. Cell 173, 1329\u20131342 e1318, https:\/\/doi.org\/10.1016\/j.cell.2018.04.004 (2018).","journal-title":"Cell"},{"key":"62089_CR20","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1016\/j.cub.2019.03.024","volume":"29","author":"M Carrillo","year":"2019","unstructured":"Carrillo, M. et al. Emotional Mirror Neurons in the Rat\u2019s Anterior Cingulate Cortex. Curr Biol 29, 1301\u20131312 e1306, https:\/\/doi.org\/10.1016\/j.cub.2019.03.024 (2019).","journal-title":"Curr Biol"},{"key":"62089_CR21","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1038\/nature14066","volume":"520","author":"TD Hanks","year":"2015","unstructured":"Hanks, T. D. et al. Distinct relationships of parietal and prefrontal cortices to evidence accumulation. Nature 520, 220\u2013223, https:\/\/doi.org\/10.1038\/nature14066 (2015).","journal-title":"Nature"},{"key":"62089_CR22","doi-asserted-by":"publisher","first-page":"4954","DOI":"10.1523\/JNEUROSCI.0105-17.2017","volume":"37","author":"AM Licata","year":"2017","unstructured":"Licata, A. M. et al. Posterior Parietal Cortex Guides Visual Decisions in Rats. J Neurosci 37, 4954\u20134966, https:\/\/doi.org\/10.1523\/JNEUROSCI.0105-17.2017 (2017).","journal-title":"J Neurosci"},{"key":"62089_CR23","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.neuroscience.2017.06.020","volume":"368","author":"H Mohan","year":"2018","unstructured":"Mohan, H., de Haan, R., Mansvelder, H. D. & de Kock, C. P. J. The posterior parietal cortex as integrative hub for whisker sensorimotor information. Neuroscience 368, 240\u2013245, https:\/\/doi.org\/10.1016\/j.neuroscience.2017.06.020 (2018).","journal-title":"Neuroscience"},{"key":"62089_CR24","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/j.tins.2016.11.006","volume":"40","author":"F Barthas","year":"2017","unstructured":"Barthas, F. & Kwan, A. C. Secondary Motor Cortex: Where \u2018Sensory\u2019 Meets \u2018Motor\u2019 in the Rodent Frontal Cortex. Trends Neurosci 40, 181\u2013193, https:\/\/doi.org\/10.1016\/j.tins.2016.11.006 (2017).","journal-title":"Trends Neurosci"},{"key":"62089_CR25","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1016\/j.neuron.2011.07.010","volume":"72","author":"JC Erlich","year":"2011","unstructured":"Erlich, J. C., Bialek, M. & Brody, C. D. A cortical substrate for memory-guided orienting in the rat. Neuron 72, 330\u2013343, https:\/\/doi.org\/10.1016\/j.neuron.2011.07.010 (2011).","journal-title":"Neuron"},{"key":"62089_CR26","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1016\/j.neuron.2011.12.028","volume":"73","author":"JR Whitlock","year":"2012","unstructured":"Whitlock, J. R., Pfuhl, G., Dagslott, N., Moser, M. B. & Moser, E. I. Functional split between parietal and entorhinal cortices in the rat. Neuron 73, 789\u2013802, https:\/\/doi.org\/10.1016\/j.neuron.2011.12.028 (2012).","journal-title":"Neuron"},{"key":"62089_CR27","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-12724-2","volume":"10","author":"A Rubin","year":"2019","unstructured":"Rubin, A. et al. Revealing neural correlates of behavior without behavioral measurements. Nat Commun 10, 4745, https:\/\/doi.org\/10.1038\/s41467-019-12724-2 (2019).","journal-title":"Nat Commun"},{"key":"62089_CR28","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1038\/nmeth.1694","volume":"8","author":"KK Ghosh","year":"2011","unstructured":"Ghosh, K. K. et al. Miniaturized integration of a fluorescence microscope. Nat Methods 8, 871\u2013878, https:\/\/doi.org\/10.1038\/nmeth.1694 (2011).","journal-title":"Nat Methods"},{"key":"62089_CR29","doi-asserted-by":"crossref","unstructured":"McInnes, L., Healy, J. & Melville, J. UMAP: Uniform Manifold Approximation and Projection for Dimension Reduction. arXiv 1802.03426 (2018).","DOI":"10.21105\/joss.00861"},{"key":"62089_CR30","doi-asserted-by":"publisher","first-page":"16","DOI":"10.3758\/BF03204445","volume":"25","author":"B Hoeks","year":"1993","unstructured":"Hoeks, B. & Levelt, W. J. M. Pupillary dilation as a measure of attention: a quantitative system analysis. Behavior Research Methods, Instruments, & Computers 25, 16\u201326, https:\/\/doi.org\/10.3758\/BF03204445 (1993).","journal-title":"Behavior Research Methods, Instruments, & Computers"},{"key":"62089_CR31","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1016\/j.neuron.2014.09.033","volume":"84","author":"J Reimer","year":"2014","unstructured":"Reimer, J. et al. Pupil fluctuations track fast switching of cortical states during quiet wakefulness. Neuron 84, 355\u2013362, https:\/\/doi.org\/10.1016\/j.neuron.2014.09.033 (2014).","journal-title":"Neuron"},{"key":"62089_CR32","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1523\/JNEUROSCI.1584-18.2018","volume":"39","author":"S Soma","year":"2019","unstructured":"Soma, S. et al. Ipsilateral-Dominant Control of Limb Movements in Rodent Posterior Parietal Cortex. J Neurosci 39, 485\u2013502, https:\/\/doi.org\/10.1523\/JNEUROSCI.1584-18.2018 (2019).","journal-title":"J Neurosci"},{"key":"62089_CR33","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/0006-8993(74)90076-6","volume":"66","author":"RD Hall","year":"1974","unstructured":"Hall, R. D. & Lindholm, E. P. Organization of motor and somatosensory neocortex in albino rat. Brain Research 66, 23\u201338 (1974).","journal-title":"Brain Research"},{"key":"62089_CR34","doi-asserted-by":"publisher","first-page":"6163","DOI":"10.1073\/pnas.1031751100","volume":"100","author":"DF Cooke","year":"2003","unstructured":"Cooke, D. F., Taylor, C. S., Moore, T. & Graziano, M. S. Complex movements evoked by microstimulation of the ventral intraparietal area. Proc Natl Acad Sci USA 100, 6163\u20136168, https:\/\/doi.org\/10.1073\/pnas.1031751100 (2003).","journal-title":"Proc Natl Acad Sci USA"},{"key":"62089_CR35","doi-asserted-by":"publisher","first-page":"13751","DOI":"10.1523\/JNEUROSCI.2985-09.2009","volume":"29","author":"DA Dombeck","year":"2009","unstructured":"Dombeck, D. A., Graziano, M. S. & Tank, D. W. Functional clustering of neurons in motor cortex determined by cellular resolution imaging in awake behaving mice. J Neurosci 29, 13751\u201313760, https:\/\/doi.org\/10.1523\/JNEUROSCI.2985-09.2009 (2009).","journal-title":"J Neurosci"},{"key":"62089_CR36","first-page":"17","volume":"39","author":"TJ Smith","year":"2013","unstructured":"Smith, T. J. & McKenna, C. M. A comparison of logistic regression pseudo R\n2 indices. General Linear Model Journal 39, 17\u201326 (2013).","journal-title":"General Linear Model Journal"},{"key":"62089_CR37","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1126\/science.aav7893","volume":"364","author":"C Stringer","year":"2019","unstructured":"Stringer, C. et al. Spontaneous behaviors drive multidimensional, brainwide activity. Science 364, 255, https:\/\/doi.org\/10.1126\/science.aav7893 (2019).","journal-title":"Science"},{"key":"62089_CR38","doi-asserted-by":"publisher","first-page":"1677","DOI":"10.1038\/s41593-019-0502-4","volume":"22","author":"S Musall","year":"2019","unstructured":"Musall, S., Kaufman, M. T., Juavinett, A. L., Gluf, S. & Churchland, A. K. Single-trial neural dynamics are dominated by richly varied movements. Nature Neuroscience 22, 1677\u20131686, https:\/\/doi.org\/10.1038\/s41593-019-0502-4 (2019).","journal-title":"Nature Neuroscience"},{"key":"62089_CR39","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1126\/science.aau2013","volume":"362","author":"B Mimica","year":"2018","unstructured":"Mimica, B., Dunn, B. A., Tombaz, T., Bojja, V. & Whitlock, J. R. Efficient cortical coding of 3D posture in freely behaving rats. Science 362, 584\u2013589, https:\/\/doi.org\/10.1126\/science.aau2013 (2018).","journal-title":"Science"},{"key":"62089_CR40","doi-asserted-by":"publisher","first-page":"1569","DOI":"10.1111\/j.1460-9568.2008.06395.x","volume":"28","author":"S Rozzi","year":"2008","unstructured":"Rozzi, S., Ferrari, P. F., Bonini, L., Rizzolatti, G. & Fogassi, L. Functional organization of inferior parietal lobule convexity in the macaque monkey: electrophysiological characterization of motor, sensory and mirror responses and their correlation with cytoarchitectonic areas. The European Journal of Neuroscience 28, 1569\u20131588, https:\/\/doi.org\/10.1111\/j.1460-9568.2008.06395.x (2008).","journal-title":"The European Journal of Neuroscience"},{"key":"62089_CR41","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/j.conb.2004.07.007","volume":"14","author":"BA Olshausen","year":"2004","unstructured":"Olshausen, B. A. & Field, D. J. Sparse coding of sensory inputs. Curr Opin Neurobiol 14, 481\u2013487, https:\/\/doi.org\/10.1016\/j.conb.2004.07.007 (2004).","journal-title":"Curr Opin Neurobiol"},{"key":"62089_CR42","doi-asserted-by":"publisher","first-page":"e63631","DOI":"10.1371\/journal.pone.0063631","volume":"8","author":"MT Lippert","year":"2013","unstructured":"Lippert, M. T., Takagaki, K., Kayser, C. & Ohl, F. W. Asymmetric multisensory interactions of visual and somatosensory responses in a region of the rat parietal cortex. PLoS One 8, e63631, https:\/\/doi.org\/10.1371\/journal.pone.0063631 (2013).","journal-title":"PLoS One"},{"key":"62089_CR43","doi-asserted-by":"publisher","first-page":"1784","DOI":"10.1038\/nn.3865","volume":"17","author":"D Raposo","year":"2014","unstructured":"Raposo, D., Kaufman, M. T. & Churchland, A. K. A category-free neural population supports evolving demands during decision-making. Nature Neuroscience 17, 1784\u20131792, https:\/\/doi.org\/10.1038\/nn.3865 (2014).","journal-title":"Nature Neuroscience"},{"key":"62089_CR44","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1038\/nature03274","volume":"433","author":"K Ohki","year":"2005","unstructured":"Ohki, K., Chung, S., Ch\u2019ng, Y. H., Kara, P. & Reid, R. C. Functional imaging with cellular resolution reveals precise micro-architecture in visual cortex. Nature 433, 597\u2013603, https:\/\/doi.org\/10.1038\/nature03274 (2005).","journal-title":"Nature"},{"key":"62089_CR45","doi-asserted-by":"publisher","first-page":"854","DOI":"10.1016\/j.neuron.2009.09.005","volume":"63","author":"DD Stettler","year":"2009","unstructured":"Stettler, D. D. & Axel, R. Representations of odor in the piriform cortex. Neuron 63, 854\u2013864, https:\/\/doi.org\/10.1016\/j.neuron.2009.09.005 (2009).","journal-title":"Neuron"},{"key":"62089_CR46","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1038\/nature10918","volume":"484","author":"CD Harvey","year":"2012","unstructured":"Harvey, C. D., Coen, P. & Tank, D. W. Choice-specific sequences in parietal cortex during a virtual-navigation decision task. Nature 484, 62\u201368, https:\/\/doi.org\/10.1038\/nature10918 (2012).","journal-title":"Nature"},{"key":"62089_CR47","doi-asserted-by":"publisher","first-page":"14117","DOI":"10.1523\/JNEUROSCI.2172-13.2013","volume":"33","author":"EE Hecht","year":"2013","unstructured":"Hecht, E. E. et al. Differences in neural activation for object-directed grasping in chimpanzees and humans. J Neurosci 33, 14117\u201314134, https:\/\/doi.org\/10.1523\/JNEUROSCI.2172-13.2013 (2013).","journal-title":"J Neurosci"},{"key":"62089_CR48","doi-asserted-by":"publisher","first-page":"459","DOI":"10.3389\/fnins.2015.00459","volume":"9","author":"W Suzuki","year":"2015","unstructured":"Suzuki, W. et al. Mirror Neurons in a New World Monkey, Common Marmoset. Front Neurosci 9, 459, https:\/\/doi.org\/10.3389\/fnins.2015.00459 (2015).","journal-title":"Front Neurosci"},{"key":"62089_CR49","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1016\/j.neuron.2009.08.028","volume":"63","author":"RA Andersen","year":"2009","unstructured":"Andersen, R. A. & Cui, H. Intention, action planning, and decision making in parietal-frontal circuits. Neuron 63, 568\u2013583, https:\/\/doi.org\/10.1016\/j.neuron.2009.08.028 (2009).","journal-title":"Neuron"},{"key":"62089_CR50","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1126\/science.1233912","volume":"340","author":"BW Brunton","year":"2013","unstructured":"Brunton, B. W., Botvinick, M. M. & Brody, C. D. Rats and humans can optimally accumulate evidence for decision-making. Science 340, 95\u201398, https:\/\/doi.org\/10.1126\/science.1233912 (2013).","journal-title":"Science"},{"key":"62089_CR51","doi-asserted-by":"publisher","first-page":"1672","DOI":"10.1038\/nn.4403","volume":"19","author":"AS Morcos","year":"2016","unstructured":"Morcos, A. S. & Harvey, C. D. History-dependent variability in population dynamics during evidence accumulation in cortex. Nature Neuroscience 19, 1672\u20131681, https:\/\/doi.org\/10.1038\/nn.4403 (2016).","journal-title":"Nature Neuroscience"},{"key":"62089_CR52","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-01356-z","volume":"8","author":"EJ Hwang","year":"2017","unstructured":"Hwang, E. J., Dahlen, J. E., Mukundan, M. & Komiyama, T. History-based action selection bias in posterior parietal cortex. Nat Commun 8, 1242, https:\/\/doi.org\/10.1038\/s41467-017-01356-z (2017).","journal-title":"Nat Commun"},{"key":"62089_CR53","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1038\/nature25510","volume":"554","author":"A Akrami","year":"2018","unstructured":"Akrami, A., Kopec, C. D., Diamond, M. E. & Brody, C. D. Posterior parietal cortex represents sensory history and mediates its effects on behaviour. Nature 554, 368\u2013372, https:\/\/doi.org\/10.1038\/nature25510 (2018).","journal-title":"Nature"},{"issue":"Suppl 1","key":"62089_CR54","doi-asserted-by":"publisher","first-page":"10647","DOI":"10.1073\/pnas.1201891109","volume":"109","author":"LA Krubitzer","year":"2012","unstructured":"Krubitzer, L. A. & Seelke, A. M. Cortical evolution in mammals: the bane and beauty of phenotypic variability. Proc Natl Acad Sci USA 109(Suppl 1), 10647\u201310654, https:\/\/doi.org\/10.1073\/pnas.1201891109 (2012).","journal-title":"Proc Natl Acad Sci USA"},{"key":"62089_CR55","doi-asserted-by":"publisher","first-page":"4386","DOI":"10.1523\/JNEUROSCI.6063-11.2012","volume":"32","author":"Q Wang","year":"2012","unstructured":"Wang, Q., Sporns, O. & Burkhalter, A. Network analysis of corticocortical connections reveals ventral and dorsal processing streams in mouse visual cortex. J Neurosci 32, 4386\u20134399, https:\/\/doi.org\/10.1523\/JNEUROSCI.6063-11.2012 (2012).","journal-title":"J Neurosci"},{"key":"62089_CR56","doi-asserted-by":"publisher","unstructured":"Hovde, K., Gianatti, M., Witter, M. P. & Whitlock, J. R. Architecture and organization of mouse posterior parietal cortex relative to extrastriate areas. The European Journal of Neuroscience, https:\/\/doi.org\/10.1111\/ejn.14280 (2018).","DOI":"10.1111\/ejn.14280"},{"key":"62089_CR57","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1002\/cne.902940210","volume":"294","author":"RL Reep","year":"1990","unstructured":"Reep, R. L., Goodwin, G. S. & Corwin, J. V. Topographic organization in the corticocortical connections of medial agranular cortex in rats. The Journal of Comparative Neurology 294, 262\u2013280, https:\/\/doi.org\/10.1002\/cne.902940210 (1990).","journal-title":"The Journal of Comparative Neurology"},{"key":"62089_CR58","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1007\/BF00227280","volume":"100","author":"RL Reep","year":"1994","unstructured":"Reep, R. L., Chandler, H. C., King, V. & Corwin, J. V. Rat posterior parietal cortex: topography of corticocortical and thalamic connections. Experimental Brain Research 100, 67\u201384 (1994).","journal-title":"Experimental Brain Research"},{"key":"62089_CR59","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1146\/annurev.neuro.20.1.25","volume":"20","author":"SP Wise","year":"1997","unstructured":"Wise, S. P., Boussaoud, D., Johnson, P. B. & Caminiti, R. Premotor and parietal cortex: corticocortical connectivity and combinatorial computations. Annual Rev Neurosci 20, 25\u201342, https:\/\/doi.org\/10.1146\/annurev.neuro.20.1.25 (1997).","journal-title":"Annual Rev Neurosci"},{"key":"62089_CR60","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1016\/S0959-4388(97)80037-2","volume":"7","author":"G Rizzolatti","year":"1997","unstructured":"Rizzolatti, G., Fogassi, L. & Gallese, V. Parietal cortex: from sight to action. Curr Opin Neurobiol 7, 562\u2013567 (1997).","journal-title":"Curr Opin Neurobiol"},{"key":"62089_CR61","doi-asserted-by":"publisher","first-page":"38","DOI":"10.3389\/fnsys.2019.00038","volume":"13","author":"GM Olsen","year":"2019","unstructured":"Olsen, G. M. et al. Organization of Posterior Parietal-Frontal Connections in the Rat. Front Syst Neurosci 13, 38, https:\/\/doi.org\/10.3389\/fnsys.2019.00038 (2019).","journal-title":"Front Syst Neurosci"},{"key":"62089_CR62","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.cell.2019.05.022","volume":"178","author":"L Kingsbury","year":"2019","unstructured":"Kingsbury, L. et al. Correlated Neural Activity and Encoding of Behavior across Brains of Socially Interacting Animals. Cell 178, 429\u2013446 e416, https:\/\/doi.org\/10.1016\/j.cell.2019.05.022 (2019).","journal-title":"Cell"},{"key":"62089_CR63","doi-asserted-by":"publisher","first-page":"e12534","DOI":"10.1111\/gbb.12534","volume":"18","author":"MH Monfils","year":"2019","unstructured":"Monfils, M. H. & Agee, L. A. Insights from social transmission of information in rodents. Genes Brain Behav 18, e12534, https:\/\/doi.org\/10.1111\/gbb.12534 (2019).","journal-title":"Genes Brain Behav"},{"key":"62089_CR64","doi-asserted-by":"publisher","first-page":"915","DOI":"10.1038\/nature08389","volume":"462","author":"T Xu","year":"2009","unstructured":"Xu, T. et al. Rapid formation and selective stabilization of synapses for enduring motor memories. Nature 462, 915\u2013919, https:\/\/doi.org\/10.1038\/nature08389 (2009).","journal-title":"Nature"},{"key":"62089_CR65","doi-asserted-by":"crossref","unstructured":"Bennett C. et al. Higher-Order Thalamic Circuits Channel Parallel Streams of Visual Information in Mice. Neuron 102(2), 477\u2013492.e5\u00a0(2019).","DOI":"10.1016\/j.neuron.2019.02.010"},{"key":"62089_CR66","doi-asserted-by":"publisher","unstructured":"Zhou, P. et al. Efficient and accurate extraction of in vivo calcium signals from microendoscopic video data. Elife 7, https:\/\/doi.org\/10.7554\/eLife.28728 (2018).","DOI":"10.7554\/eLife.28728"},{"key":"62089_CR67","doi-asserted-by":"publisher","first-page":"e1005423","DOI":"10.1371\/journal.pcbi.1005423","volume":"13","author":"J Friedrich","year":"2017","unstructured":"Friedrich, J., Zhou, P. & Paninski, L. Fast online deconvolution of calcium imaging data. PLoS Comput Biol 13, e1005423, https:\/\/doi.org\/10.1371\/journal.pcbi.1005423 (2017).","journal-title":"PLoS Comput Biol"},{"key":"62089_CR68","doi-asserted-by":"publisher","first-page":"1102","DOI":"10.1016\/j.celrep.2017.10.013","volume":"21","author":"L Sheintuch","year":"2017","unstructured":"Sheintuch, L. et al. Tracking the Same Neurons across Multiple Days in Ca(2+) Imaging Data. Cell Rep 21, 1102\u20131115, https:\/\/doi.org\/10.1016\/j.celrep.2017.10.013 (2017).","journal-title":"Cell Rep"},{"key":"62089_CR69","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1080\/01969727408546059","volume":"4","author":"JC Dunn","year":"1974","unstructured":"Dunn, J. C. Well-Separated Clusters and Optimal Fuzzy Partitions. Journal of Cybernetics 4, 95\u2013104, https:\/\/doi.org\/10.1080\/01969727408546059 (1974).","journal-title":"Journal of Cybernetics"},{"key":"62089_CR70","doi-asserted-by":"publisher","first-page":"370","DOI":"10.2307\/2344614","volume":"135","author":"JA Nelder","year":"1972","unstructured":"Nelder, J. A. & Wedderburn, W. M. Generalized Linear Models. Journal of the Royal Statistical Society. Series A 135, 370\u2013384 (1972).","journal-title":"Journal of the Royal Statistical Society. Series A"},{"key":"62089_CR71","doi-asserted-by":"publisher","first-page":"e38011","DOI":"10.1371\/journal.pone.0038011","volume":"7","author":"A Cardona","year":"2012","unstructured":"Cardona, A. et al. TrakEM2 software for neural circuit reconstruction. PLoS One 7, e38011, https:\/\/doi.org\/10.1371\/journal.pone.0038011 (2012).","journal-title":"PLoS One"},{"key":"62089_CR72","unstructured":"Paxinos, G. & Franklin K. Paxino\u2019s and Franklin\u2019s the Mouse Brain in Stereotaxic Coordinates. 4th edn, (Academic Press, 2012)."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-020-62089-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-020-62089-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-020-62089-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,6]],"date-time":"2022-12-06T03:45:20Z","timestamp":1670298320000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-020-62089-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,27]]},"references-count":72,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2020,12]]}},"alternative-id":["62089"],"URL":"https:\/\/doi.org\/10.1038\/s41598-020-62089-6","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/646414","asserted-by":"object"}]},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,27]]},"assertion":[{"value":"1 October 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 March 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 March 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"5559"}}