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Root-knot nematodes (RKNs) cause severe economic losses in many crops worldwide, although little is known about the mechanisms that control plant growth and defense responses during nematode attack. Upon investigation of\n                    <jats:italic>Arabidopsis thaliana<\/jats:italic>\n                    infected with RKN (\n                    <jats:italic>Meloidogyne incognita<\/jats:italic>\n                    ), we observed that the atypical transcription factor\n                    <jats:italic>DP-E2F-like 1<\/jats:italic>\n                    (\n                    <jats:italic>DEL1<\/jats:italic>\n                    ) repressed salicylic acid (SA) accumulation in RKN-induced galls. The\n                    <jats:italic>DEL1<\/jats:italic>\n                    -deficient Arabidopsis mutant (\n                    <jats:italic>del1-1<\/jats:italic>\n                    ) exhibited excessive SA accumulation in galls and is more resistant to RKN infection. In addition, excessive lignification was observed in galls of\n                    <jats:italic>del1-1<\/jats:italic>\n                    . On the other hand, the root growth of\n                    <jats:italic>del1-1<\/jats:italic>\n                    is reduced after RKN infection. Taken together, these findings suggest that\n                    <jats:italic>DEL1<\/jats:italic>\n                    plays an important role in the balance between plant growth and defense responses to RKN infection by controlling SA accumulation and lignification.\n                  <\/jats:p>","DOI":"10.1038\/s41598-020-65733-3","type":"journal-article","created":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T06:03:14Z","timestamp":1590991394000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["The atypical E2F transcription factor DEL1 modulates growth\u2013defense tradeoffs of host plants during root-knot nematode infection"],"prefix":"10.1038","volume":"10","author":[{"given":"Satoru","family":"Nakagami","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kentaro","family":"Saeki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kei","family":"Toda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Ishida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shinichiro","family":"Sawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,6,1]]},"reference":[{"key":"65733_CR1","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1146\/annurev.phyto.050908.135202","volume":"47","author":"AC Vlot","year":"2009","unstructured":"Vlot, A. 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