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Thirty healthy individuals randomly received three consecutive sessions of active or sham anodal ctDCS during split-belt treadmill training. Motor performance and strides to steady-state performance were evaluated before (baseline), during (adaptation), and after (de-adaptation) the intervention. The outcomes were measured one week later to assess absolute learning and during the intervention to evaluate cumulative, consecutive, and session-specific effects. Data were analysed using linear mixed-effects regression models. During adaptation, there was no significant difference in absolute learning between the groups (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). During de-adaptation, a significant difference in absolute learning between the groups (<jats:italic>p<\/jats:italic>\u2009=\u20090.03) indicated slower de-adaptation with anodal ctDCS. Pre-planned secondary analysis revealed that anodal ctDCS significantly reduced the cumulative (<jats:italic>p<\/jats:italic>\u2009=\u20090.01) and consecutive-session effect (<jats:italic>p<\/jats:italic>\u2009=\u20090.01) on immediate adaptation. There were significant cumulative (<jats:italic>p<\/jats:italic>\u2009=\u20090.02) and session-specific effects (<jats:italic>p<\/jats:italic>\u2009=\u20090.003) on immediate de-adaptation. Repeated anodal ctDCS does not enhance motor learning measured during adaptation to a split-belt treadmill task. However, it influences the maintenance of learnt walking patterns, suggesting that it may be beneficial in maintaining therapeutic effects.<\/jats:p>","DOI":"10.1038\/s41598-020-68825-2","type":"journal-article","created":{"date-parts":[[2020,7,16]],"date-time":"2020-07-16T10:04:22Z","timestamp":1594893862000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Cerebellar transcranial direct current stimulation for learning a novel split-belt treadmill task: a randomised controlled trial"],"prefix":"10.1038","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5135-1682","authenticated-orcid":false,"given":"Nitika","family":"Kumari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0955-5702","authenticated-orcid":false,"given":"Denise","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1109-5493","authenticated-orcid":false,"given":"Usman","family":"Rashid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3153-2953","authenticated-orcid":false,"given":"Alain C.","family":"Vandal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul F.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nada","family":"Signal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,7,16]]},"reference":[{"key":"68825_CR1","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1586\/ern.12.121","volume":"12","author":"HJ Block","year":"2012","unstructured":"Block, H. 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