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Air pollution, particularly fine particulate matter (\u2264\u20092.5\u00a0\u03bcm in aerodynamic diameter [PM<jats:sub>2.5<\/jats:sub>])\u00a0has demonstrated an increase in adverse cardiovascular events. This study aimed to assess the cardiovascular response to personal exposure to different levels of PM<jats:sub>2.5<\/jats:sub>. This prospective cohort study enrolled healthy volunteers aged \u2265\u200918\u00a0years with no cardiovascular disease. Study subjects carried personal exposure monitor of PM<jats:sub>2.5<\/jats:sub>, digital thermo-hygrometer for temperature and humidity, 24-h blood pressure monitor, and continuous electrocardiogram monitor. Measurements were repeated twice with an interval of 6\u201312\u00a0months. Statistical models consisted of generalized estimation equations to various repeated measures of each subject. A total of 22 subjects were enrolled in this study between July 2018 and January 2019. Measurement was performed twice in all participants, and a total of 36 data were collected except for insufficient data collection. The mean age of the study population was 41.6\u00a0years, and 95% of the subjects were females. No study subjects had hypertension or other cardiovascular diseases. The average systolic blood pressure increased with higher PM<jats:sub>2.5<\/jats:sub> levels with marginal significance (0.22\u00a0mmHg [95% confidential intervals \u2212\u20090.04 to 0.48\u00a0mmHg] per 10\u00a0\u03bcg\/m<jats:sup>3<\/jats:sup> of PM<jats:sub>2.5<\/jats:sub>). All parameters for heart rate variability significantly decreased with a higher level of PM<jats:sub>2.5<\/jats:sub>. In this study, we measured individual personal exposure to PM<jats:sub>2.5<\/jats:sub> by using a portable device. We found that 24-h exposure to high levels of PM<jats:sub>2.5<\/jats:sub> was associated with a significant decrease in heart rate variability, suggesting impaired autonomous nervous function.<\/jats:p>","DOI":"10.1038\/s41598-020-73205-x","type":"journal-article","created":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T10:04:06Z","timestamp":1601978646000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Personal exposure to fine particulate air pollutants impacts blood pressure and heart rate variability"],"prefix":"10.1038","volume":"10","author":[{"given":"Dong-Hoon","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun-Hwa","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si-Hyuck","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oh Kyung","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Joo","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Hwan","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young-Seok","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jongbae","family":"Heo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung-Muk","family":"Yi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae-Jin","family":"Youn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In-Ho","family":"Chae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,10,6]]},"reference":[{"key":"73205_CR1","unstructured":"WHO\/Health topics\/Air pollution [Internet]. 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