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Recent genomic studies showed that\n                    <jats:italic>B. pseudomallei<\/jats:italic>\n                    originated in Australia and spread to Asia, with phylogenetic evidence of repeated reintroduction of\n                    <jats:italic>B. pseudomallei<\/jats:italic>\n                    across countries bordered by the Mekong River and the Malay Peninsula. We present the first whole-genome sequences of\n                    <jats:italic>B. pseudomallei<\/jats:italic>\n                    isolates from Myanmar: nine clinical and seven environmental isolates. We used large-scale comparative genomics to assess the genetic diversity, phylogeography and potential origins of\n                    <jats:italic>B. pseudomallei<\/jats:italic>\n                    in Myanmar. Global phylogenetics demonstrated that Myanmar isolates group in two distantly related clades that reside in a more ancestral Asian clade with high amounts of genetic diversity. The diversity of\n                    <jats:italic>B. pseudomallei<\/jats:italic>\n                    from Myanmar and divergence within our global phylogeny suggest that the original introduction of\n                    <jats:italic>B. pseudomallei<\/jats:italic>\n                    to Myanmar was not a recent event. Our study provides new insights into global patterns of\n                    <jats:italic>B. pseudomallei<\/jats:italic>\n                    dissemination, most notably the dynamic nature of movement of\n                    <jats:italic>B. pseudomallei<\/jats:italic>\n                    within densely populated Southeast Asia. The role of anthropogenic influences in both ancient and more recent dissemination of\n                    <jats:italic>B. pseudomallei<\/jats:italic>\n                    to Myanmar and elsewhere in Southeast Asia and globally requires further study.\n                  <\/jats:p>","DOI":"10.1038\/s41598-020-73545-8","type":"journal-article","created":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T06:04:13Z","timestamp":1601532253000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Myanmar Burkholderia pseudomallei strains are genetically diverse and originate from Asia with phylogenetic evidence of reintroductions from neighbouring countries"],"prefix":"10.1038","volume":"10","author":[{"given":"Jessica R.","family":"Webb","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mo Mo","family":"Win","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khwar Nyo","family":"Zin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyi Kyi Nyein","family":"Win","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thin Thin","family":"Wah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A.","family":"Ashley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Smithuis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myo Maung Maung","family":"Swe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Mayo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart J.","family":"Currie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A. 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