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To clarify this, we studied auditory event-related potentials (AEPs) to stimuli of different intensity in patients with FM and healthy controls (HCs), considering the effects of attention mechanisms and medication. We performed two experiments: In study 1 (n\u2009=\u200950 FM, 60 HCs), the stimuli were presented randomly within the sequence; in study 2 (n\u2009=\u200928 FM, 30 HCs), they were presented in blocks of the same intensity. We analyzed intensity and group effects on N1-P2 amplitude and, only for the FM group, the effect of medication and the correlation between AEPs and clinical variables. Contrary to the expectation, the patients showed a trend of reduced AEPs to the loudest tones (study 1) or no significant differences with the HCs (study 2). Medication with central effects significantly reduced AEPs, while no significant relationships between the N1-P2 amplitude\/intensity function and patients\u2019 symptoms were observed. The findings do not provide evidence of augmented auditory processing in FM. Nevertheless, given the observed effect of medication, the role of sensory amplification as an underlying pathophysiological mechanism in fibromyalgia cannot be discarded.<\/jats:p>","DOI":"10.1038\/s41598-020-78377-0","type":"journal-article","created":{"date-parts":[[2020,12,14]],"date-time":"2020-12-14T11:04:43Z","timestamp":1607943883000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Effects of intensity, attention and medication on auditory-evoked potentials in patients with fibromyalgia"],"prefix":"10.1038","volume":"10","author":[{"given":"N.","family":"Samartin-Veiga","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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