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Emergency department patients complaining of ocular FBs were enrolled. In the irrigation group (n\u2009=\u200952), pain was evaluated with a visual analog scale before and after irrigation, and the presence of FBs was determined under a slit-lamp. In the nonirrigation group (n\u2009=\u200927), the evaluations were performed upon arrival. The corneal FB retention rate was found significantly lower in the irrigation (13\/52, 25%) than in the nonirrigation groups (13\/27, 48%; <jats:italic>P<\/jats:italic>\u2009=\u20090.04). After irrigation, those without FBs had more patients experiencing pain reduction (67%) compared to those with retained FBs (46%; <jats:italic>P<\/jats:italic>\u2009=\u20090.14) and had a greater magnitude of change in pain score (mean\u2009\u00b1\u2009SD, \u2212\u20092.6\u2009\u00b1\u20092.7 vs. \u2212\u20090.7\u2009\u00b1\u20091.4; <jats:italic>P<\/jats:italic>\u2009=\u20090.02). An improvement in ocular pain score\u2009\u2265\u20095 points after irrigation predicted the absence of FBs with a negative predictive value of 100%. Eye irrigation significantly lowered corneal FB retention; if ocular pain decreased considerably, the probability of retained FBs was low, making irrigation-associated pain score reduction a feasible diagnostic method to exclude FB retention without needing specialized ophthalmic examinations.<\/jats:p>","DOI":"10.1038\/s41598-021-02989-3","type":"journal-article","created":{"date-parts":[[2021,12,3]],"date-time":"2021-12-03T11:03:41Z","timestamp":1638529421000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Eye irrigation as a first-line treatment and diagnostic method for emergency department patients who complain of ocular foreign bodies"],"prefix":"10.1038","volume":"11","author":[{"given":"Hung-Da","family":"Chou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuan-Jen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eugene Yu-Chuan","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jui-Yen","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Po-Han","family":"Yeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yen-Ting","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi-Tung","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi-Chun","family":"Lai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Chi","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yih-Shiou","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ching-Hsi","family":"Hsiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,12,3]]},"reference":[{"key":"2989_CR1","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.1038\/eye.2017.113","volume":"31","author":"JC Buchan","year":"2017","unstructured":"Buchan, J. 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