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We enrolled 84 healthy eyes. Participants with a history of any ophthalmic disease (except high myopia) or intraocular surgery were excluded from the study. An experienced examiner performed OCTA using disc-centered 6\u2009\u00d7\u20096\u00a0mm scans. All examinations were conducted twice at 5-min intervals at the initial visit and repeated at least 6\u00a0months later. For short-term repeatability, the coefficient of variation (CV) was 2.94\u20134.22% and the intraclass correlation coefficient (ICC) was 0.840\u20130.934. For long-term repeatability, the CV was 2.73\u20133.84% and the ICC was 0.737\u20130.934. Multivariate analyses showed that the axial length (AL) (B\u2009=\u20090.970; p\u2009=\u20090.002) and mean signal strength (SS) (B\u2009=\u2009\u2212\u20092.028; p\u2009&lt;\u20090.001) significantly affected long-term repeatability. Measurements of peripapillary OCTA parameters exhibited excellent short-term and good long-term repeatability in healthy individuals. The mean SS and AL affected long-term repeatability and should be considered while interpreting peripapillary OCTA images.<\/jats:p>","DOI":"10.1038\/s41598-021-03469-4","type":"journal-article","created":{"date-parts":[[2021,12,13]],"date-time":"2021-12-13T06:04:31Z","timestamp":1639375471000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Long-term repeatability of peripapillary optical coherence tomography angiography measurements in healthy eyes"],"prefix":"10.1038","volume":"11","author":[{"given":"Woo Hyuk","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min-Woo","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min-Su","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheon Kuk","family":"Ryu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung-Yeul","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,12,13]]},"reference":[{"key":"3469_CR1","doi-asserted-by":"publisher","first-page":"2163","DOI":"10.1097\/iae.0000000000000765","volume":"35","author":"RF Spaide","year":"2015","unstructured":"Spaide, R. 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