{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T15:02:32Z","timestamp":1711378952522},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T00:00:00Z","timestamp":1641945600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T00:00:00Z","timestamp":1641945600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Henan Province Medical Science and Technology Research Plan","award":["SBGJ2018031"],"award-info":[{"award-number":["SBGJ2018031"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>It is essential to identify high risk transient ischemic attack (TIA) patients. The previous study reported that the CSR (comprehensive stroke recurrence) model, a neuroimaging model, had a high predictive ability of recurrent stroke. The aims of this study were to validate the predictive value of CSR model in TIA patients and compare the predictive ability with ABCD<jats:sup>3<\/jats:sup>-I score. Data were analyzed from the prospective hospital-based database of patients with TIA which defined by the World Health Organization time-based criteria. The predictive outcome was stroke occurrence at 90\u00a0days. The receiver-operating characteristic (ROC) curves were plotted and the C statistics were calculated as a measure of predictive ability. Among 1186 eligible patients, the mean age was 57.28\u2009\u00b1\u200912.17\u00a0years, and 474 (40.0%) patients had positive diffusion-weighted imaging (DWI). There were 118 (9.9%) patients who had stroke within 90\u00a0days. In 1186 TIA patients, The C statistic of CSR model (0.754; 95% confidence interval [CI] 0.729\u20130.778) was similar with that of ABCD<jats:sup>3<\/jats:sup>-I score (0.717; 95% CI 0.691\u20130.743; Z\u2009=\u20091.400; <jats:italic>P<\/jats:italic>\u2009=\u20090.1616). In 474 TIA patients with positive DWI, C statistic of CSR model (0.725; 95% CI 0.683\u20130.765) was statistically higher than that of ABCD<jats:sup>3<\/jats:sup>-I score (0.626; 95% CI 0.581\u20130.670; Z\u2009=\u20092.294; <jats:italic>P<\/jats:italic>\u2009=\u20090.0245). The CSR model had good predictive value for assessing stroke risk after TIA, and it had a higher predictive value than ABCD<jats:sup>3<\/jats:sup>-I score for assessing stroke risk for TIA patients with positive DWI.\n<\/jats:p>","DOI":"10.1038\/s41598-021-04405-2","type":"journal-article","created":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T11:02:59Z","timestamp":1641985379000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Validation of CSR model to predict stroke risk after transient ischemic attack"],"prefix":"10.1038","volume":"12","author":[{"given":"Lu","family":"Zhao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuang","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lulu","family":"Pei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Fang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shilei","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuming","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,1,12]]},"reference":[{"key":"4405_CR1","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1159\/000341696","volume":"40","author":"P von Weitzel-Mudersbach","year":"2013","unstructured":"von Weitzel-Mudersbach, P., Andersen, G., Hundborg, H. 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