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The aim of this study was to establish the reliability of SWE in young children, define reference data on healthy ones and compare the shear modulus of healthy and spastic muscles from cerebral palsy (CP). The reproducibility is evaluated: at rest, on 7 children without any musculoskeletal pathology by 3 different operators, on 2 muscles: biceps brachii long head and medial gastrocnemius. The comparison study was made, on the same 2 muscles, at rest and under passive stretching, with a control group (29 healthy children), a spastic group (spastic muscles of 16 children from CP) and a non-spastic group (non-spastic muscles of 14 children from CP). The intra-operator reliability and inter-operator reliability, in terms of standard deviation, were 0.6\u00a0kPa (11.2% coefficient of variation (CV)) and 0.8\u00a0kPa (14.9% CV) for the biceps, respectively, and 0.4\u00a0kPa (11.5% CV) and 0.5\u00a0kPa (13.8% CV) for the gastrocnemius. At rest, no significant difference was found. Under passive stretching, the non-spastic CP biceps were significantly stiffer than the control ones (p\u2009=\u20090.033). Spastic gastrocnemius had a higher shear modulus than in the control muscles (p\u2009=\u20090.0003) or the non-spastic CP muscles (p\u2009=\u20090.017). CP stretched medial gastrocnemius presented an abnormally high shear moduli for 50% of patients.<\/jats:p>","DOI":"10.1038\/s41598-021-82005-w","type":"journal-article","created":{"date-parts":[[2021,2,11]],"date-time":"2021-02-11T06:05:48Z","timestamp":1613023548000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Ultrasound shearwave elastography to characterize muscles of healthy and cerebral palsy children"],"prefix":"10.1038","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8495-1409","authenticated-orcid":false,"given":"Pauline","family":"Lallemant-Dudek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7049-2405","authenticated-orcid":false,"given":"Claudio","family":"Vergari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Dubois","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e9ronique","family":"Forin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rapha\u00ebl","family":"Vialle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wafa","family":"Skalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,2,11]]},"reference":[{"key":"82005_CR1","first-page":"8","volume":"109","author":"P Rosenbaum","year":"2007","unstructured":"Rosenbaum, P. et al. 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