{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T07:00:05Z","timestamp":1781766005570,"version":"3.54.5"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T00:00:00Z","timestamp":1614729600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T00:00:00Z","timestamp":1614729600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National research foundation of Korea","doi-asserted-by":"crossref","award":["2020R1A2C4002594"],"award-info":[{"award-number":["2020R1A2C4002594"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"crossref"}]},{"name":"National research fountion of Korea","award":["NRF-2018-R1D1A1A02085328"],"award-info":[{"award-number":["NRF-2018-R1D1A1A02085328"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Previous studies have suggested an increased risk of ischemic heart disease related to air pollution. This study aimed to explore both the short-term and long-term effects of air pollutants on the risk of ischemic heart disease after adjusting for meteorological factors. The Korean National Health Insurance Service-Health Screening Cohort from 2002 to 2013 was used. Overall, 2155 participants with ischemic heart disease and 8620 control participants were analyzed. The meteorological data and air pollution data, including SO<jats:sub>2<\/jats:sub> (ppm), NO<jats:sub>2<\/jats:sub> (ppm), O<jats:sub>3<\/jats:sub> (ppm), CO (ppm), and particulate matter (PM)<jats:sub>10<\/jats:sub> (\u03bcg\/m<jats:sup>3<\/jats:sup>), were analyzed using conditional logistic regression. Subgroup analyses were performed according to age, sex, income, and region of residence. One-month exposure to SO<jats:sub>2<\/jats:sub> was related to 1.36-fold higher odds for ischemic heart disease (95% confidence interval [95% CI] 1.06\u20131.75). One-year exposure to SO<jats:sub>2<\/jats:sub>, O<jats:sub>3<\/jats:sub>, and PM<jats:sub>10<\/jats:sub> was associated with 1.58- (95% CI 1.01\u20132.47), 1.53- (95% CI 1.27\u20131.84), and 1.14 (95% CI 1.02\u20131.26)-fold higher odds for ischemic heart disease. In subgroup analyses, the\u2009\u2265\u200960-year-old group, men, individuals with low income, and urban groups demonstrated higher odds associated with 1-month exposure to SO<jats:sub>2<\/jats:sub>. Short-term exposure to SO<jats:sub>2<\/jats:sub> and long-term exposure to SO<jats:sub>2,<\/jats:sub> O<jats:sub>3<\/jats:sub>, and PM<jats:sub>10<\/jats:sub> were related to ischemic heart disease.<\/jats:p>","DOI":"10.1038\/s41598-021-84587-x","type":"journal-article","created":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T11:02:36Z","timestamp":1614769356000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Short and long term exposure to air pollution increases the risk of ischemic heart disease"],"prefix":"10.1038","volume":"11","author":[{"given":"So Young","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Hoon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jee Hye","family":"Wee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanyang","family":"Min","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Min","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seungdo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyo Geun","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,3]]},"reference":[{"key":"84587_CR1","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1016\/j.amjmed.2014.04.015","volume":"127","author":"JE Dalen","year":"2014","unstructured":"Dalen, J. E., Alpert, J. S., Goldberg, R. J. & Weinstein, R. S. The epidemic of the 20(th) century: Coronary heart disease. Am. J. Med. 127, 807\u2013812. https:\/\/doi.org\/10.1016\/j.amjmed.2014.04.015 (2014).","journal-title":"Am. J. Med."},{"key":"84587_CR2","doi-asserted-by":"publisher","unstructured":"DALYs, G. B. D. & Collaborators, H. Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990\u20132017: A systematic analysis for the Global Burden of Disease Study 2017. Lancet 392, 1859\u20131922, https:\/\/doi.org\/10.1016\/S0140-6736(18)32335-3 (2018).","DOI":"10.1016\/S0140-6736(18)32335-3"},{"key":"84587_CR3","doi-asserted-by":"publisher","first-page":"e67","DOI":"10.1161\/CIR.0000000000000558","volume":"137","author":"EJ Benjamin","year":"2018","unstructured":"Benjamin, E. J. et al. Heart disease and stroke statistics-2018 update: A report from the American Heart Association. Circulation 137, e67\u2013e492. https:\/\/doi.org\/10.1161\/CIR.0000000000000558 (2018).","journal-title":"Circulation"},{"key":"84587_CR4","doi-asserted-by":"publisher","first-page":"1613","DOI":"10.1016\/j.jacc.2010.06.038","volume":"56","author":"JW McEvoy","year":"2010","unstructured":"McEvoy, J. W. et al. Coronary artery calcium progression: An important clinical measurement? A review of published reports. J. Am. Coll. Cardiol. 56, 1613\u20131622. https:\/\/doi.org\/10.1016\/j.jacc.2010.06.038 (2010).","journal-title":"J. Am. Coll. Cardiol."},{"key":"84587_CR5","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/j.ijcard.2013.11.048","volume":"170","author":"P Gargiulo","year":"2014","unstructured":"Gargiulo, P. et al. Ischemic heart disease in systemic inflammatory diseases. An appraisal. Int. J. Cardiol. 170, 286\u2013290. https:\/\/doi.org\/10.1016\/j.ijcard.2013.11.048 (2014).","journal-title":"Int. J. Cardiol."},{"key":"84587_CR6","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1007\/s11883-016-0575-4","volume":"18","author":"T Mandviwala","year":"2016","unstructured":"Mandviwala, T., Khalid, U. & Deswal, A. Obesity and cardiovascular disease: A risk factor or a risk marker?. Curr. Atheroscler. Rep. 18, 21. https:\/\/doi.org\/10.1007\/s11883-016-0575-4 (2016).","journal-title":"Curr. Atheroscler. Rep."},{"key":"84587_CR7","doi-asserted-by":"publisher","first-page":"1401","DOI":"10.1093\/ije\/dyr129","volume":"40","author":"M Roerecke","year":"2011","unstructured":"Roerecke, M. et al. Heavy drinking occasions in relation to ischaemic heart disease mortality\u2014An 11\u201322 year follow-up of the 1984 and 1995 US National Alcohol Surveys. Int. J. Epidemiol. 40, 1401\u20131410. https:\/\/doi.org\/10.1093\/ije\/dyr129 (2011).","journal-title":"Int. J. Epidemiol."},{"key":"84587_CR8","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.1016\/j.jacc.2003.12.047","volume":"43","author":"JA Ambrose","year":"2004","unstructured":"Ambrose, J. A. & Barua, R. S. The pathophysiology of cigarette smoking and cardiovascular disease: An update. J. Am. Coll. Cardiol. 43, 1731\u20131737. https:\/\/doi.org\/10.1016\/j.jacc.2003.12.047 (2004).","journal-title":"J. Am. Coll. Cardiol."},{"key":"84587_CR9","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1385\/ct:1:4:285","volume":"1","author":"TP Dalton","year":"2001","unstructured":"Dalton, T. P. et al. Dioxin exposure is an environmental risk factor for ischemic heart disease. Cardiovasc. Toxicol. 1, 285\u2013298. https:\/\/doi.org\/10.1385\/ct:1:4:285 (2001).","journal-title":"Cardiovasc. Toxicol."},{"key":"84587_CR10","doi-asserted-by":"publisher","first-page":"2443","DOI":"10.1161\/CIRCULATIONAHA.106.636977","volume":"114","author":"CA Pope 3rd","year":"2006","unstructured":"Pope, C. A. 3rd. et al. Ischemic heart disease events triggered by short-term exposure to fine particulate air pollution. Circulation 114, 2443\u20132448. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.106.636977 (2006).","journal-title":"Circulation"},{"key":"84587_CR11","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1289\/ehp.1509777","volume":"124","author":"GD Thurston","year":"2016","unstructured":"Thurston, G. D. et al. Ischemic heart disease mortality and long-term exposure to source-related components of U.S. fine particle air pollution. Environ. Health Perspect. 124, 785\u2013794. https:\/\/doi.org\/10.1289\/ehp.1509777 (2016).","journal-title":"Environ. Health Perspect."},{"key":"84587_CR12","doi-asserted-by":"publisher","first-page":"153944","DOI":"10.1016\/j.metabol.2019.07.008","volume":"100S","author":"A Combes","year":"2019","unstructured":"Combes, A. & Franchineau, G. Fine particle environmental pollution and cardiovascular diseases. Metabolism 100S, 153944. https:\/\/doi.org\/10.1016\/j.metabol.2019.07.008 (2019).","journal-title":"Metabolism"},{"key":"84587_CR13","doi-asserted-by":"publisher","first-page":"1412","DOI":"10.1016\/j.envpol.2019.06.078","volume":"252","author":"Y Lu","year":"2019","unstructured":"Lu, Y. et al. Assessing the association between fine particulate matter (PM2.5) constituents and cardiovascular diseases in a mega-city of Pakistan. Environ. Pollut. 252, 1412\u20131422. https:\/\/doi.org\/10.1016\/j.envpol.2019.06.078 (2019).","journal-title":"Environ. Pollut."},{"key":"84587_CR14","doi-asserted-by":"publisher","first-page":"1404","DOI":"10.1016\/j.envpol.2018.08.030","volume":"242","author":"W Zhang","year":"2018","unstructured":"Zhang, W. et al. Triggering of cardiovascular hospital admissions by fine particle concentrations in New York state: Before, during, and after implementation of multiple environmental policies and a recession. Environ. Pollut. 242, 1404\u20131416. https:\/\/doi.org\/10.1016\/j.envpol.2018.08.030 (2018).","journal-title":"Environ. Pollut."},{"key":"84587_CR15","doi-asserted-by":"publisher","first-page":"113173","DOI":"10.1016\/j.envpol.2019.113173","volume":"255","author":"M Shamsipour","year":"2019","unstructured":"Shamsipour, M. et al. National and sub-national exposure to ambient fine particulate matter (PM2.5) and its attributable burden of disease in Iran from 1990 to 2016. Environ. Pollut. 255, 113173. https:\/\/doi.org\/10.1016\/j.envpol.2019.113173 (2019).","journal-title":"Environ. Pollut."},{"key":"84587_CR16","doi-asserted-by":"publisher","first-page":"1710","DOI":"10.1016\/j.envpol.2018.09.089","volume":"243","author":"J Li","year":"2018","unstructured":"Li, J. et al. Estimation of PM2.5 mortality burden in China with new exposure estimation and local concentration-response function. Environ. Pollut. 243, 1710\u20131718. https:\/\/doi.org\/10.1016\/j.envpol.2018.09.089 (2018).","journal-title":"Environ. Pollut."},{"key":"84587_CR17","doi-asserted-by":"publisher","first-page":"107012","DOI":"10.1289\/EHP4757","volume":"127","author":"PLS Ljungman","year":"2019","unstructured":"Ljungman, P. L. S. et al. Long-term exposure to particulate air pollution, black carbon, and their source components in relation to ischemic heart disease and stroke. Environ. Health Perspect. 127, 107012. https:\/\/doi.org\/10.1289\/EHP4757 (2019).","journal-title":"Environ. Health Perspect."},{"key":"84587_CR18","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.envres.2018.02.033","volume":"164","author":"J Huang","year":"2018","unstructured":"Huang, J. et al. The burden of ischemic heart disease related to ambient air pollution exposure in a coastal city in South China. Environ. Res. 164, 255\u2013261. https:\/\/doi.org\/10.1016\/j.envres.2018.02.033 (2018).","journal-title":"Environ. Res."},{"key":"84587_CR19","doi-asserted-by":"publisher","first-page":"1106","DOI":"10.1016\/j.envpol.2018.06.045","volume":"241","author":"Z Sun","year":"2018","unstructured":"Sun, Z., Chen, C., Xu, D. & Li, T. Effects of ambient temperature on myocardial infarction: A systematic review and meta-analysis. Environ. Pollut. 241, 1106\u20131114. https:\/\/doi.org\/10.1016\/j.envpol.2018.06.045 (2018).","journal-title":"Environ. Pollut."},{"key":"84587_CR20","doi-asserted-by":"publisher","first-page":"8270","DOI":"10.1038\/s41598-019-44618-0","volume":"9","author":"HG Choi","year":"2019","unstructured":"Choi, H. G., Min, C. & Kim, S. Y. Air pollution increases the risk of SSNHL: A nested case-control study using meteorological data and national sample cohort data. Sci. Rep. 9, 8270. https:\/\/doi.org\/10.1038\/s41598-019-44618-0 (2019).","journal-title":"Sci. Rep."},{"key":"84587_CR21","doi-asserted-by":"publisher","first-page":"412","DOI":"10.21053\/ceo.2018.01774","volume":"12","author":"SY Kim","year":"2019","unstructured":"Kim, S. Y., Min, C., Oh, D. J. & Choi, H. G. Tobacco smoking and alcohol consumption are related to benign parotid tumor: A nested case-control study using a national health screening cohort. Clin. Exp. Otorhinolaryngol. 12, 412\u2013419. https:\/\/doi.org\/10.21053\/ceo.2018.01774 (2019).","journal-title":"Clin. Exp. Otorhinolaryngol."},{"key":"84587_CR22","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1001\/jamaoto.2019.0742","volume":"145","author":"SY Kim","year":"2019","unstructured":"Kim, S. Y., Kong, I. G., Min, C. & Choi, H. G. Association of air pollution with increased risk of peritonsillar abscess formation. JAMA Otolaryngol. Head Neck Surg. 145, 530\u2013535. https:\/\/doi.org\/10.1001\/jamaoto.2019.0742 (2019).","journal-title":"JAMA Otolaryngol. Head Neck Surg."},{"key":"84587_CR23","unstructured":"Team, K. A. M. Air Korea."},{"key":"84587_CR24","doi-asserted-by":"publisher","first-page":"1060","DOI":"10.1001\/jamainternmed.2018.2310","volume":"178","author":"S Choi","year":"2018","unstructured":"Choi, S. et al. Association of obesity or weight change with coronary heart disease among young adults in South Korea. JAMA Intern. Med. 178, 1060\u20131068. https:\/\/doi.org\/10.1001\/jamainternmed.2018.2310 (2018).","journal-title":"JAMA Intern. Med."},{"key":"84587_CR25","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1016\/j.jaip.2019.10.043","volume":"8","author":"SY Kim","year":"2020","unstructured":"Kim, S. Y., Min, C., Oh, D. J. & Choi, H. G. Bidirectional association between GERD and asthma: Two longitudinal follow-up studies using a national sample cohort. J. Allergy Clin. Immunol. Pract. 8, 1005\u20131013. https:\/\/doi.org\/10.1016\/j.jaip.2019.10.043 (2020).","journal-title":"J. Allergy Clin. Immunol. Pract."},{"key":"84587_CR26","doi-asserted-by":"publisher","first-page":"4248","DOI":"10.1038\/s41598-020-61240-7","volume":"10","author":"SY Kim","year":"2020","unstructured":"Kim, S. Y., Oh, D. J., Park, B. & Choi, H. G. Bell\u2019s palsy and obesity, alcohol consumption and smoking: A nested case-control study using a national health screening cohort. Sci. Rep. 10, 4248. https:\/\/doi.org\/10.1038\/s41598-020-61240-7 (2020).","journal-title":"Sci. Rep."},{"key":"84587_CR27","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1093\/aje\/kwq433","volume":"173","author":"H Quan","year":"2011","unstructured":"Quan, H. et al. Updating and validating the Charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries. Am. J. Epidemiol. 173, 676\u2013682. https:\/\/doi.org\/10.1093\/aje\/kwq433 (2011).","journal-title":"Am. J. Epidemiol."},{"key":"84587_CR28","doi-asserted-by":"publisher","first-page":"1130","DOI":"10.1097\/01.mlr.0000182534.19832.83","volume":"43","author":"H Quan","year":"2005","unstructured":"Quan, H. et al. Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Med. Care 43, 1130\u20131139. https:\/\/doi.org\/10.1097\/01.mlr.0000182534.19832.83 (2005).","journal-title":"Med. Care"},{"key":"84587_CR29","doi-asserted-by":"publisher","first-page":"1774","DOI":"10.1177\/2047487316651352","volume":"23","author":"G Li","year":"2016","unstructured":"Li, G., Zeng, Q. & Pan, X. Disease burden of ischaemic heart disease from short-term outdoor air pollution exposure in Tianjin, 2002\u20132006. Eur. J. Prev. Cardiol. 23, 1774\u20131782. https:\/\/doi.org\/10.1177\/2047487316651352 (2016).","journal-title":"Eur. J. Prev. Cardiol."},{"key":"84587_CR30","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.115.002742","author":"W Li","year":"2016","unstructured":"Li, W. et al. Short-term exposure to air pollution and biomarkers of oxidative stress: The Framingham Heart Study. J. Am. Heart Assoc. https:\/\/doi.org\/10.1161\/JAHA.115.002742 (2016).","journal-title":"J. Am. Heart Assoc."},{"key":"84587_CR31","doi-asserted-by":"publisher","first-page":"e196553","DOI":"10.1001\/jamanetworkopen.2019.6553","volume":"2","author":"M Wang","year":"2019","unstructured":"Wang, M. et al. Association of estimated long-term exposure to air pollution and traffic proximity with a marker for coronary atherosclerosis in a nationwide study in China. JAMA Netw. Open 2, e196553. https:\/\/doi.org\/10.1001\/jamanetworkopen.2019.6553 (2019).","journal-title":"JAMA Netw. Open"},{"key":"84587_CR32","doi-asserted-by":"publisher","first-page":"57001","DOI":"10.1289\/EHP3325","volume":"127","author":"M Wang","year":"2019","unstructured":"Wang, M. et al. Long-term exposure to ambient ozone and progression of subclinical arterial disease: The multi-ethnic study of atherosclerosis and air pollution. Environ. Health Perspect. 127, 57001. https:\/\/doi.org\/10.1289\/EHP3325 (2019).","journal-title":"Environ. Health Perspect."},{"key":"84587_CR33","doi-asserted-by":"publisher","first-page":"696","DOI":"10.1016\/S0140-6736(16)00378-0","volume":"388","author":"JD Kaufman","year":"2016","unstructured":"Kaufman, J. D. et al. Association between air pollution and coronary artery calcification within six metropolitan areas in the USA (the Multi-Ethnic Study of Atherosclerosis and Air Pollution): A longitudinal cohort study. Lancet 388, 696\u2013704. https:\/\/doi.org\/10.1016\/S0140-6736(16)00378-0 (2016).","journal-title":"Lancet"},{"key":"84587_CR34","doi-asserted-by":"publisher","first-page":"e1002738","DOI":"10.1371\/journal.pmed.1002738","volume":"16","author":"Y Tian","year":"2019","unstructured":"Tian, Y. et al. Association between temperature variability and daily hospital admissions for cause-specific cardiovascular disease in urban China: A national time-series study. PLoS Med. 16, e1002738. https:\/\/doi.org\/10.1371\/journal.pmed.1002738 (2019).","journal-title":"PLoS Med."},{"key":"84587_CR35","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1097\/01.ede.0000134875.15919.0f","volume":"15","author":"J Schwartz","year":"2004","unstructured":"Schwartz, J., Samet, J. M. & Patz, J. A. Hospital admissions for heart disease: The effects of temperature and humidity. Epidemiology 15, 755\u2013761. https:\/\/doi.org\/10.1097\/01.ede.0000134875.15919.0f (2004).","journal-title":"Epidemiology"},{"key":"84587_CR36","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1016\/j.envres.2018.08.002","volume":"167","author":"M Loizeau","year":"2018","unstructured":"Loizeau, M. et al. Does the air pollution model influence the evidence of socio-economic disparities in exposure and susceptibility?. Environ. Res. 167, 650\u2013661. https:\/\/doi.org\/10.1016\/j.envres.2018.08.002 (2018).","journal-title":"Environ. Res."},{"key":"84587_CR37","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph16173127","author":"J Fairburn","year":"2019","unstructured":"Fairburn, J., Schule, S. A., Dreger, S., Karla Hilz, L. & Bolte, G. Social inequalities in exposure to ambient air pollution: A systematic review in the WHO European Region. Int. J. Environ. Res. Public Health. https:\/\/doi.org\/10.3390\/ijerph16173127 (2019).","journal-title":"Int. J. Environ. Res. Public Health."},{"key":"84587_CR38","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1136\/jech.58.1.2","volume":"58","author":"FW Lipfert","year":"2004","unstructured":"Lipfert, F. W. Air pollution and poverty: Does the sword cut both ways?. J. Epidemiol. Community Health 58, 2\u20133. https:\/\/doi.org\/10.1136\/jech.58.1.2 (2004).","journal-title":"J. Epidemiol. Community Health"},{"key":"84587_CR39","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/s0009-9120(96)00155-5","volume":"30","author":"GJ Soleas","year":"1997","unstructured":"Soleas, G. J., Diamandis, E. P. & Goldberg, D. M. Resveratrol: A molecule whose time has come? And gone?. Clin. Biochem. 30, 91\u2013113. https:\/\/doi.org\/10.1016\/s0009-9120(96)00155-5 (1997).","journal-title":"Clin. Biochem."},{"key":"84587_CR40","doi-asserted-by":"publisher","first-page":"1523","DOI":"10.1016\/0140-6736(92)91277-f","volume":"339","author":"S Renaud","year":"1992","unstructured":"Renaud, S. & de Lorgeril, M. Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet 339, 1523\u20131526. https:\/\/doi.org\/10.1016\/0140-6736(92)91277-f (1992).","journal-title":"Lancet"},{"key":"84587_CR41","doi-asserted-by":"publisher","DOI":"10.3390\/nu8050250","author":"D Bonnefont-Rousselot","year":"2016","unstructured":"Bonnefont-Rousselot, D. Resveratrol and cardiovascular diseases. Nutrients. https:\/\/doi.org\/10.3390\/nu8050250 (2016).","journal-title":"Nutrients."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-021-84587-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-021-84587-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-021-84587-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,3]],"date-time":"2022-12-03T04:40:48Z","timestamp":1670042448000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-021-84587-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,3]]},"references-count":41,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,12]]}},"alternative-id":["84587"],"URL":"https:\/\/doi.org\/10.1038\/s41598-021-84587-x","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,3]]},"assertion":[{"value":"14 October 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 February 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 March 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"5108"}}