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Thus, we implemented a cluster-randomized controlled trial to determine the effectiveness of two educational-plus-therapeutic interventions, in Nutrition and WASH\/Malaria, in reducing anemia. We compared them to (1) a test-and-treat intervention and (2) with each other. A block randomization was performed to allocate 6 isolated hamlets to 3 study arms. A difference-in-difference technique, using Fit Generalized estimating models, was used to determine differences between the children successfully followed in all groups, between 2015 and 2016. We found no significant differences in anemia\u00b4s and hemoglobin variability between educational and the control group. However, the WASH\/Malaria group had 22.8% higher prevalence of anemia when compared with the Nutrition group, having also higher prevalence of <jats:italic>P. falciparum<\/jats:italic>. Thus, our results suggest that adding a 12-month educational Nutrition or a WASH\/Malaria component to a test-and-treat approach may have a limited effect in controlling anemia. Possibly, the intensity and duration of the educational interventions were not sufficient to observe the amount of behavior change needed to stop transmission and improve the general child feeding practices.<\/jats:p>","DOI":"10.1038\/s41598-021-85006-x","type":"journal-article","created":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T11:03:12Z","timestamp":1615374192000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Effectiveness of Nutrition and WASH\/malaria educational community-based interventions in reducing anemia in children from Angola"],"prefix":"10.1038","volume":"11","author":[{"given":"Cl\u00e1udia","family":"Fan\u00e7ony","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c2nia","family":"Soares","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Lavinha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrique","family":"Barros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Brito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,10]]},"reference":[{"key":"85006_CR1","doi-asserted-by":"publisher","first-page":"2527","DOI":"10.1093\/jn\/130.10.2527","volume":"130","author":"ML Dreyfuss","year":"2000","unstructured":"Dreyfuss, M. 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