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Biplanar radiographies were acquired at baseline, immediate post-operatively, 1-year and 2-year follow-up, and 3D reconstruction of the spine and pelvis was performed. NTK and THK showed different global sagittal alignment, as well as differences compared to controls. AIS with THK at baseline had higher SVA\/SFD (2.0\u2009\u00b1\u20092.9 vs\u2009\u2212\u20090.4\u2009\u00b1\u20091.9; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05) and OD-HA (0.2\u2009\u00b1\u20091.4\u00b0 vs\u2009\u2212\u20091.3\u2009\u00b1\u20091.6\u00b0; <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05) than controls, indicating that THK had compensated balance with unusual forward leaning posture. Immediately post-operation, SVA\/SFD remained high (1.3\u2009\u00b1\u20093.0) while OD-HA reversed (\u2212\u20091.2\u2009\u00b1\u20091.7\u00b0), indicating that THK patients had found partially compensated balance. After 2-yeas, both SVA\/SFD (\u2212\u20091.3\u2009\u00b1\u20092.1) and OD-HA (\u2212\u20091.4\u2009\u00b1\u20090.9\u00b0) were normalized. The changes in global sagittal alignment and mechanism of balance are different in AIS with or without THK. As the head plays a critical role on balance during immediate and delayed post-operation, OD-HA can be complementary parameter for assessing global balance during post-operative follow-up of AIS patients with THK.<\/jats:p>","DOI":"10.1038\/s41598-021-85782-6","type":"journal-article","created":{"date-parts":[[2021,3,18]],"date-time":"2021-03-18T16:47:41Z","timestamp":1616086061000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Global sagittal alignment after surgery of right thoracic idiopathic scoliosis in adolescents and adults with and without thoracic hypokyphosis"],"prefix":"10.1038","volume":"11","author":[{"given":"Kwong Hang","family":"Yeung","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gene Chi Wai","family":"Man","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wafa","family":"Skalli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zongshan","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivian Wing Yin","family":"Hung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alec Lik Hang","family":"Hung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsz Ping","family":"Lam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bobby Kin Wah","family":"Ng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack Chun Yiu","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Vergari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Winnie Chiu Wing","family":"Chu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,3,18]]},"reference":[{"key":"85782_CR1","doi-asserted-by":"publisher","first-page":"15030","DOI":"10.1038\/nrdp.2015.30","volume":"1","author":"JC Cheng","year":"2015","unstructured":"Cheng, J. 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