{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T09:49:37Z","timestamp":1793785777568,"version":"4.6.1"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,3,18]],"date-time":"2021-03-18T00:00:00Z","timestamp":1616025600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,3,18]],"date-time":"2021-03-18T00:00:00Z","timestamp":1616025600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["18DZ2201900"],"award-info":[{"award-number":["18DZ2201900"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["19441912300"],"award-info":[{"award-number":["19441912300"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["17441903800"],"award-info":[{"award-number":["17441903800"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008111","name":"Hainan Provincial Department of Science and Technology","doi-asserted-by":"publisher","award":["ZDYF2018022"],"award-info":[{"award-number":["ZDYF2018022"]}],"id":[{"id":"10.13039\/501100008111","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shanghai Jiao Tong University School of Medicine Two-hundred Talent","award":["20161420"],"award-info":[{"award-number":["20161420"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["61672341"],"award-info":[{"award-number":["61672341"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["61973211"],"award-info":[{"award-number":["61973211"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["51911540479"],"award-info":[{"award-number":["51911540479"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Science and Technology Commission of Fujian Province","award":["2018H0032"],"award-info":[{"award-number":["2018H0032"]}]},{"name":"Science and Technology Commission of Quanzhou municipality","award":["2018Z028"],"award-info":[{"award-number":["2018Z028"]}]},{"name":"SJTU Medical and Engineering Cross Fund","award":["YG2017ZD03"],"award-info":[{"award-number":["YG2017ZD03"]}]},{"name":"Interdisciplinary Program of Shanghai Jiao Tong University","award":["ZH2018QNB31"],"award-info":[{"award-number":["ZH2018QNB31"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Genioplasty is the main way to treat diseases such as chin asymmetry, dysplasia and overdevelopment, which involve the three-dimensional direction abnormalities of the chin. Since this kind of surgery mainly uses intraoral incisions, the narrow surgical field of intraoral incisions and the surrounding important neurovascular tissues make it easy for complications, to occur during the osteotomy process, which results in greater surgical risks. The first craniofacial-plastic surgical robot (CPSR-I) system is developed to complete the precise positioning and improve the surgeon's force perception ability. The Kalman filtering method is adopted to reduce the interference of sensor signal noise. An adaptive fuzzy control system, which has strong robustness and adaptability to the environment, is designed to improve the stability of robot-assisted surgical operations. To solve the problem of the depth perception, we propose an automatic bone drilling control strategy that combines position and force conditions to ensure that the robot can automatically stop when the bone is penetrated. On the basis of model surgery and animal experiments, preliminary experiments were carried out clinically. Based on the early results of 6 patients, the robot-assisted approach appears to be a safe and effective strategy for genioplasty.<\/jats:p>","DOI":"10.1038\/s41598-021-85889-w","type":"journal-article","created":{"date-parts":[[2021,3,18]],"date-time":"2021-03-18T16:47:41Z","timestamp":1616086061000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Preliminary clinical experience of robot-assisted surgery in treatment with genioplasty"],"prefix":"10.1038","volume":"11","author":[{"given":"Li","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunyong","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaozheng","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Chai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Le","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,18]]},"reference":[{"key":"85889_CR1","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1097\/00006534-199802000-00035","volume":"101","author":"K Satoh","year":"1998","unstructured":"Satoh, K. Mandibular contouring surgery by angular contouring combined with genioplasty in orientals. Plast. Reconstr. Surg. 101, 461\u2013472 (1998).","journal-title":"Plast. Reconstr. Surg."},{"key":"85889_CR2","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1097\/01.PRS.0000135904.40986.F8","volume":"114","author":"H Jin","year":"2004","unstructured":"Jin, H. & Kim, B. G. Mandibular angle reduction versus mandible reduction. Plast. Reconstr. Surg. 114, 1263\u20131269 (2004).","journal-title":"Plast. Reconstr. Surg."},{"key":"85889_CR3","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1016\/S0140-6736(16)30592-X","volume":"388","author":"JW Yaxley","year":"2016","unstructured":"Yaxley, J. W. et al. Robot-assisted laparoscopic prostatectomy versus open radical retropubic prostatectomy: Early outcomes from a randomised controlled phase 3 study. Lancet 388, 1057\u20131066. https:\/\/doi.org\/10.1016\/S0140-6736(16)30592-X (2016).","journal-title":"Lancet"},{"key":"85889_CR4","doi-asserted-by":"publisher","first-page":"147","DOI":"10.5301\/hipint.5000418","volume":"27","author":"C Suarez-Ahedo","year":"2017","unstructured":"Suarez-Ahedo, C. et al. Robotic-arm assisted total hip arthroplasty results in smaller acetabular cup size in relation to the femoral head size: a matched-pair controlled study. Hip Int. 27, 147\u2013152. https:\/\/doi.org\/10.5301\/hipint.5000418 (2017).","journal-title":"Hip Int."},{"key":"85889_CR5","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1097\/Brs.0000000000000680","volume":"40","author":"HJ Kim","year":"2015","unstructured":"Kim, H. J. et al. Monitoring the quality of robot-assisted pedicle screw fixation in the lumbar spine by using a cumulative summation test. Spine 40, 87\u201394. https:\/\/doi.org\/10.1097\/Brs.0000000000000680 (2015).","journal-title":"Spine"},{"key":"85889_CR6","doi-asserted-by":"publisher","first-page":"e746","DOI":"10.1097\/SCS.0000000000002180","volume":"26","author":"H Gui","year":"2015","unstructured":"Gui, H. et al. A novel system for navigation-and robot-assisted craniofacial surgery: Establishment of the principle prototype. J. Craniofac. Surg. 26, e746-749. https:\/\/doi.org\/10.1097\/SCS.0000000000002180 (2015).","journal-title":"J. Craniofac. Surg."},{"key":"85889_CR7","first-page":"133","volume":"1230","author":"M Klein","year":"2001","unstructured":"Klein, M. et al. Robot assisted insertion of craniofacial implants: Clinical experience. Comput. Assist. Radiol. Surg. 1230, 133\u2013138 (2001).","journal-title":"Comput. Assist. Radiol. Surg."},{"key":"85889_CR8","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1055\/s-2005-870908","volume":"48","author":"G Eggers","year":"2005","unstructured":"Eggers, G. et al. Robot-assisted craniotomy. Minim. Invas. Neurosurg. 48, 154\u2013158 (2005).","journal-title":"Minim. Invas. Neurosurg."},{"key":"85889_CR9","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1016\/j.bjoms.2015.07.019","volume":"53","author":"KW Baek","year":"2015","unstructured":"Baek, K. W. et al. Clinical applicability of robot-guided contact-free laser osteotomy in cranio-maxillo-facial surgery: In-vitro simulation and in-vivo surgery in minipig mandibles. Br. J. Oral Maxillofac. Surg. 53, 976\u2013981. https:\/\/doi.org\/10.1016\/j.bjoms.2015.07.019 (2015).","journal-title":"Br. J. Oral Maxillofac. Surg."},{"key":"85889_CR10","doi-asserted-by":"publisher","first-page":"1980","DOI":"10.1016\/j.jcms.2017.09.001","volume":"45","author":"SY Woo","year":"2017","unstructured":"Woo, S. Y. et al. Autonomous bone reposition around anatomical landmark for robot-assisted orthognathic surgery. J. Craniomaxillofac. Surg. 45, 1980\u20131988. https:\/\/doi.org\/10.1016\/j.jcms.2017.09.001 (2017).","journal-title":"J. Craniomaxillofac. Surg."},{"key":"85889_CR11","doi-asserted-by":"publisher","first-page":"e1997","DOI":"10.1002\/rcs.1997","volume":"15","author":"Q Ma","year":"2019","unstructured":"Ma, Q. et al. Development and preliminary evaluation of an autonomous surgical system for oral and maxillofacial surgery. Int. J. Med. Robot. Comput. Assist. Surg. 15, e1997. https:\/\/doi.org\/10.1002\/rcs.1997 (2019).","journal-title":"Int. J. Med. Robot. Comput. Assist. Surg."},{"key":"85889_CR12","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.jcms.2015.10.024","volume":"44","author":"L Lin","year":"2016","unstructured":"Lin, L. et al. Mandibular angle split osteotomy based on a novel augmented reality navigation using specialized robot-assisted arms: A feasibility study. J. Craniomaxillofac. Surg. 44, 215\u2013223. https:\/\/doi.org\/10.1016\/j.jcms.2015.10.024 (2016).","journal-title":"J. Craniomaxillofac. Surg."},{"key":"85889_CR13","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1080\/13645706.2016.1216864","volume":"26","author":"Y Shi","year":"2017","unstructured":"Shi, Y. et al. A study of an assisting robot for mandible plastic surgery based on augmented reality. Minim. Invasive Ther. Allied Technol. 26, 23\u201330. https:\/\/doi.org\/10.1080\/13645706.2016.1216864 (2017).","journal-title":"Minim. Invasive Ther. Allied Technol."},{"key":"85889_CR14","doi-asserted-by":"publisher","first-page":"1228","DOI":"10.1007\/s00266-017-0900-5","volume":"41","author":"C Zhou","year":"2017","unstructured":"Zhou, C. et al. Robot-Assisted surgery for mandibular angle split osteotomy using augmented reality: Preliminary results on clinical animal experiment. Aesthetic Plast. Surg. 41, 1228\u20131236. https:\/\/doi.org\/10.1007\/s00266-017-0900-5 (2017).","journal-title":"Aesthetic Plast. Surg."},{"key":"85889_CR15","doi-asserted-by":"publisher","first-page":"1676","DOI":"10.1007\/s10439-018-2053-3","volume":"46","author":"A Gijbels","year":"2018","unstructured":"Gijbels, A. et al. In-human robot-assisted retinal vein cannulation, a world first. Ann. Biomed. Eng. 46, 1676\u20131685. https:\/\/doi.org\/10.1007\/s10439-018-2053-3 (2018).","journal-title":"Ann. Biomed. Eng."},{"key":"85889_CR16","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1016\/j.eururo.2014.12.008","volume":"67","author":"B Yuh","year":"2015","unstructured":"Yuh, B. et al. Systematic review and cumulative analysis of oncologic and functional outcomes after robot-assisted radical cystectomy. Eur. Urol. 67, 402\u2013422. https:\/\/doi.org\/10.1016\/j.eururo.2014.12.008 (2015).","journal-title":"Eur. Urol."},{"key":"85889_CR17","doi-asserted-by":"publisher","first-page":"1048","DOI":"10.1016\/j.surg.2009.09.007","volume":"146","author":"SW Kang","year":"2009","unstructured":"Kang, S. W. et al. Robotic thyroid surgery using a gasless, transaxillary approach and the da Vinci S system: The operative outcomes of 338 consecutive patients. Surgery 146, 1048\u20131055. https:\/\/doi.org\/10.1016\/j.surg.2009.09.007 (2009).","journal-title":"Surgery"},{"key":"85889_CR18","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-019-02230-3","author":"D VanSickle","year":"2019","unstructured":"VanSickle, D. et al. Electrode placement accuracy in robot-assisted asleep deep brain stimulation. Ann. Biomed. Eng. https:\/\/doi.org\/10.1007\/s10439-019-02230-3 (2019).","journal-title":"Ann. Biomed. Eng."},{"key":"85889_CR19","doi-asserted-by":"publisher","DOI":"10.1126\/scirobotics.aal4916","author":"S Weber","year":"2017","unstructured":"Weber, S. et al. Instrument flight to the inner ear. Sci. Robot. https:\/\/doi.org\/10.1126\/scirobotics.aal4916 (2017).","journal-title":"Sci. Robot."},{"key":"85889_CR20","doi-asserted-by":"publisher","first-page":"1772","DOI":"10.1056\/NEJMoa0911341","volume":"362","author":"AC Lo","year":"2010","unstructured":"Lo, A. C. et al. Robot-assisted therapy for long-term upper-limb impairment after stroke. N. Engl. J. Med. 362, 1772\u20131783. https:\/\/doi.org\/10.1056\/NEJMoa0911341 (2010).","journal-title":"N. Engl. J. Med."},{"key":"85889_CR21","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1097\/PRS.0000000000000550","volume":"134","author":"T Alrasheed","year":"2014","unstructured":"Alrasheed, T., Liu, J., Hanasono, M. M., Butler, C. E. & Selber, J. C. Robotic microsurgery: Validating an assessment tool and plotting the learning curve. Plast. Reconstr. Surg. 134, 794\u2013803. https:\/\/doi.org\/10.1097\/PRS.0000000000000550 (2014).","journal-title":"Plast. Reconstr. Surg."},{"key":"85889_CR22","doi-asserted-by":"publisher","first-page":"1978","DOI":"10.1097\/PRS.0b013e3181f448e3","volume":"126","author":"JC Selber","year":"2010","unstructured":"Selber, J. C. Transoral robotic reconstruction of oropharyngeal defects: A case series. Plast. Reconstr. Surg. 126, 1978\u20131987. https:\/\/doi.org\/10.1097\/PRS.0b013e3181f448e3 (2010).","journal-title":"Plast. Reconstr. Surg."},{"key":"85889_CR23","doi-asserted-by":"publisher","first-page":"e28","DOI":"10.1097\/SLA.0000000000001397","volume":"266","author":"A Toesca","year":"2017","unstructured":"Toesca, A. et al. Robotic nipple-sparing mastectomy and immediate breast reconstruction with implant: First report of surgical technique. Ann. Surg. 266, e28\u2013e30. https:\/\/doi.org\/10.1097\/SLA.0000000000001397 (2017).","journal-title":"Ann. Surg."},{"key":"85889_CR24","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.1097\/PRS.0b013e31824ecc0b","volume":"129","author":"JC Selber","year":"2012","unstructured":"Selber, J. C., Baumann, D. P. & Holsinger, F. C. Robotic latissimus dorsi muscle harvest: A case series. Plast. Reconstr. Surg. 129, 1305\u20131312. https:\/\/doi.org\/10.1097\/PRS.0b013e31824ecc0b (2012).","journal-title":"Plast. Reconstr. Surg."},{"key":"85889_CR25","unstructured":"Standardization, I. O. F. Medical Devices: Application of Risk Management to Medical Devices (2019)."},{"key":"85889_CR26","unstructured":"Commission, I. E. Medical Electrical Equipment: Part 2\u201377: Particular Requirements for the Basic Safety and Essential Performance of Medical Robots for Surgery (2019)."},{"key":"85889_CR27","doi-asserted-by":"publisher","DOI":"10.1126\/scirobotics.aam8638","author":"G-Z Yang","year":"2017","unstructured":"Yang, G.-Z. et al. Medical robotics-Regulatory, ethical, and legal considerations for increasing levels of autonomy. Science robotics. https:\/\/doi.org\/10.1126\/scirobotics.aam8638 (2017).","journal-title":"Science robotics."},{"key":"85889_CR28","doi-asserted-by":"publisher","DOI":"10.1126\/scirobotics.aar7650","author":"G-Z Yang","year":"2018","unstructured":"Yang, G.-Z. et al. The grand challenges of science robotics. Sci. Robot. https:\/\/doi.org\/10.1126\/scirobotics.aar7650 (2018).","journal-title":"Sci. Robot."},{"key":"85889_CR29","doi-asserted-by":"crossref","unstructured":"Zollo, L., Siciliano, B., Luca, A. D. & Guglielmelli, E. PD Control with On-Line Gravity Compensation for Robots with Flexible Links. (2007).","DOI":"10.23919\/ECC.2007.7068344"},{"key":"85889_CR30","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1016\/j.jprocont.2014.02.020","volume":"24","author":"O Garpinger","year":"2014","unstructured":"Garpinger, O., Hagglund, T. & Astrom, K. J. Performance and robustness trade-offs in PID control. J. Process. Contrib. 24, 568\u2013577. https:\/\/doi.org\/10.1016\/j.jprocont.2014.02.020 (2014).","journal-title":"J. Process. Contrib."},{"key":"85889_CR31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1163\/156855395X00265","volume":"9","author":"S Ishikawa","year":"1994","unstructured":"Ishikawa, S. A method of autonomous mobile robot navigation by using fuzzy control. Adv. Robot. 9, 1\u201325 (1994).","journal-title":"Adv. Robot."},{"key":"85889_CR32","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1109\/3477.658577","volume":"28","author":"YC Jin","year":"1998","unstructured":"Jin, Y. C. Decentralized adaptive fuzzy control of robot manipulators. IEEE Trans. Syst. Man. Cyber. B 28, 47\u201357. https:\/\/doi.org\/10.1109\/3477.658577 (1998).","journal-title":"IEEE Trans. Syst. Man. Cyber. B"},{"key":"85889_CR33","doi-asserted-by":"publisher","first-page":"4943","DOI":"10.1016\/j.asoc.2011.06.005","volume":"11","author":"AF Amer","year":"2011","unstructured":"Amer, A. F., Sallam, E. A. & Elawady, W. M. Adaptive fuzzy sliding mode control using supervisory fuzzy control for 3 DOF planar robot manipulators. Appl. Soft Comput. 11, 4943\u20134953. https:\/\/doi.org\/10.1016\/j.asoc.2011.06.005 (2011).","journal-title":"Appl. Soft Comput."},{"key":"85889_CR34","unstructured":"Jian, G., Wu, G. & Guo, S. in 2015 IEEE International Conference on Mechatronics and Automation (ICMA)."},{"key":"85889_CR35","unstructured":"Jing, J., Wang, Y. & Huang, Y. in IEEE International Conference on Mechatronics & Automation."},{"key":"85889_CR36","doi-asserted-by":"publisher","DOI":"10.1088\/1755-1315\/69\/1\/012186","author":"S Lin","year":"2017","unstructured":"Lin, S. & Wang, G. L. Fuzzy PID control algorithm based on PSO and application in BLDC motor. IOP C Ser. Earth Environ. https:\/\/doi.org\/10.1088\/1755-1315\/69\/1\/012186 (2017).","journal-title":"IOP C Ser. Earth Environ."},{"key":"85889_CR37","doi-asserted-by":"publisher","first-page":"1806","DOI":"10.1097\/Scs.0b013e31822e8064","volume":"22","author":"M Zhu","year":"2011","unstructured":"Zhu, M., Chai, G., Zhang, Y., Ma, X. F. & Gan, J. L. Registration strategy using occlusal splint based on augmented reality for mandibular angle oblique split osteotomy. J. Cranio. Surg. 22, 1806\u20131809. https:\/\/doi.org\/10.1097\/Scs.0b013e31822e8064 (2011).","journal-title":"J. Cranio. Surg."},{"key":"85889_CR38","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1097\/SAP.0000000000000644","volume":"77","author":"M Zhu","year":"2016","unstructured":"Zhu, M. et al. Effectiveness of a novel augmented reality-based navigation system in treatment of orbital hypertelorism. Ann Plast. Surg. 77, 662\u2013668. https:\/\/doi.org\/10.1097\/SAP.0000000000000644 (2016).","journal-title":"Ann Plast. Surg."},{"key":"85889_CR39","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1016\/j.jcms.2014.10.019","volume":"43","author":"M Qu","year":"2015","unstructured":"Qu, M. et al. Precise positioning of an intraoral distractor using augmented reality in patients with hemifacial microsomia. J. Cranio. Maxill. Surg. 43, 106\u2013112. https:\/\/doi.org\/10.1016\/j.jcms.2014.10.019 (2015).","journal-title":"J. Cranio. Maxill. Surg."},{"key":"85889_CR40","doi-asserted-by":"publisher","DOI":"10.1038\/srep42365","author":"M Zhu","year":"2017","unstructured":"Zhu, M. et al. A novel augmented reality system for displaying inferior alveolar nerve bundles in maxillofacial surgery. Sci. Rep. https:\/\/doi.org\/10.1038\/srep42365 (2017).","journal-title":"Sci. Rep."},{"key":"85889_CR41","doi-asserted-by":"publisher","first-page":"1280","DOI":"10.1016\/j.jcms.2019.04.008","volume":"47","author":"WQ Han","year":"2019","unstructured":"Han, W. Q. et al. A new method for cranial vault reconstruction: Augmented reality in synostotic plagiocephaly surgery. J. Cranio.. Maxill. Surg. 47, 1280\u20131284. https:\/\/doi.org\/10.1016\/j.jcms.2019.04.008 (2019).","journal-title":"J. Cranio.. Maxill. Surg."},{"key":"85889_CR42","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1097\/SAP.0000000000001149","volume":"79","author":"X Fu","year":"2017","unstructured":"Fu, X. et al. Standardized protocol for virtual surgical plan and 3-dimensional surgical template-assisted single-stage mandible contour surgery. Ann. Plast. Surg. 79, 236\u2013242. https:\/\/doi.org\/10.1097\/SAP.0000000000001149 (2017).","journal-title":"Ann. Plast. Surg."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-021-85889-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-021-85889-w","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-021-85889-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,3]],"date-time":"2022-12-03T05:39:00Z","timestamp":1670045940000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-021-85889-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,18]]},"references-count":42,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,12]]}},"alternative-id":["85889"],"URL":"https:\/\/doi.org\/10.1038\/s41598-021-85889-w","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,18]]},"assertion":[{"value":"28 December 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 March 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 March 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"6365"}}