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These variables included discriminative sensation through the two-point discrimination (2-PD) test, tactile acuity threshold and pressure pain threshold (PPT), and electromyographic (EMG) activity compared with a sham-tDCS (s-tDCS) in healthy individuals. A total of 100 participants were included. Fifty of the participants received the a-tDCS application of 2\u00a0mA for 20\u00a0min, whereas the remaining fifty received the s-tDCS. The 2-PD and tactile acuity threshold in thenar eminence of the hand and in the dorsal part of the foot and also, PPT and EMG activity during maximal voluntary contraction in the biceps brachii and rectus femoris were assessed before and after the tDCS application. The a-tDCS intervention was not significantly superior to the s-tDCS in any variable. However, significant within-group pre- and post-intervention differences were found in the a-tDCS, such as the tactile acuity threshold in thenar eminence of the hand, with a small effect size (<jats:italic>p<\/jats:italic>\u2009=\u2009.012, <jats:italic>d<\/jats:italic>\u2009=\u20090.20) and in the PPT of the rectus femoris, also with a small effect size (<jats:italic>p<\/jats:italic>\u2009=\u2009.001, <jats:italic>d<\/jats:italic>\u2009=\u2009\u2009\u2212\u20090.17). Regarding EMG activity, a trend towards greater activity was observed in participants with a-tDCS compared with s-tDCS, which showed a trend towards decreased EMG activity. In fact, although no differences were found between the groups, within-group differences were statistically significant in the biceps brachii pre- and postintervention (<jats:italic>p<\/jats:italic>\u2009=\u2009.023, <jats:italic>d<\/jats:italic>\u2009=\u2009\u2009\u2212\u20090.16, and <jats:italic>p<\/jats:italic>\u2009=\u2009.002, <jats:italic>d<\/jats:italic>\u2009=\u20090.18, respectively), and also in the rectus femoris, only in the a-tDCS, with a small effect size (<jats:italic>p<\/jats:italic>\u2009=\u2009.011, <jats:italic>d<\/jats:italic>\u2009=\u2009\u2009\u2212\u20090.14). This study showed no significant between-group differences in sensorimotor outcomes. A single session of tDCS in isolation appears to produce immediate effects in healthy participants on sensorimotor function; however, these effects were very small.<\/jats:p>","DOI":"10.1038\/s41598-021-85989-7","type":"journal-article","created":{"date-parts":[[2021,3,22]],"date-time":"2021-03-22T11:03:43Z","timestamp":1616411023000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Transcranial direct-current stimulation (tDCS) in the primary motor cortex and its effects on sensorimotor function: a quasi-experimental single-blind sham-controlled trial"],"prefix":"10.1038","volume":"11","author":[{"given":"Sergio","family":"Lerma-Lara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"De Cherade Montbron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathias","family":"Gu\u00e9rin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferran","family":"Cuenca-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy","family":"La Touche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,3,22]]},"reference":[{"key":"85989_CR1","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.brs.2011.03.002","volume":"5","author":"AR Brunoni","year":"2012","unstructured":"Brunoni, A. 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