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Even higher magnetic fields are considered by the Hadron Future Circular Collider (FCC-hh) design study, which plans to develop 16\u00a0T Nb<jats:sub>3<\/jats:sub>Sn bending dipoles. In such high-field magnets, the design pre-stress can reach considerable values (150\u2013200\u00a0MPa) and, since Nb<jats:sub>3<\/jats:sub>Sn is a brittle compound, this can constitute a technological difficult challenge. Due to the significant impact that a transverse load can have on the performances of a Nb<jats:sub>3<\/jats:sub>Sn magnet, CERN has launched a campaign of critical current measurements of reacted and impregnated Nb<jats:sub>3<\/jats:sub>Sn cables subjected to transverse pressure up to about 210\u00a0MPa. In this paper, results obtained on 18-strand 10-mm-wide cable sample based on a 1-mm-diameter powder-in-tube (PIT) wire are presented. The tests were carried out on a 2-m-long sample by using the FReSCa test station, at T\u2009=\u20094.3\u00a0K and background magnetic fields up to 9.6\u00a0T. For applied pressures below \u2248 130\u00a0MPa, only reversible reductions of the critical current, <jats:italic>I<\/jats:italic><jats:sub><jats:italic>c<\/jats:italic><\/jats:sub>, are observed. At higher pressures, a permanent <jats:italic>I<\/jats:italic><jats:sub><jats:italic>c<\/jats:italic><\/jats:sub> reduction occurs; such irreversible behaviour is due to the residual stresses generated by the plastic deformations of the copper stabilizer. This type of current reduction, whether reversible or not, is fully governed by the strain-induced variations of the upper critical field, <jats:italic>B<\/jats:italic><jats:sub><jats:italic>c2<\/jats:italic><\/jats:sub>. At higher pressures, estimated between 180 and 210\u00a0MPa, it is indeed plausible to believe that cracking of filaments occurs, with detrimental consequences for the Nb<jats:sub>3<\/jats:sub>Sn cable\u2019s electrical performances. The complete set of critical current data here presented, collected at different pressures and as a function of the applied magnetic field, allows for the first time to investigate the evolution of superconducting parameters such as the upper critical field <jats:italic>B<\/jats:italic><jats:sub><jats:italic>c2<\/jats:italic><\/jats:sub> in the irreversibility region, where both the effects of Cu matrix plasticization and\/or cracking of filaments may occur. The experimental approach and data interpretation have a general value and can be applied to any typology of Rutherford cable.<\/jats:p>","DOI":"10.1038\/s41598-021-86563-x","type":"journal-article","created":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T10:03:08Z","timestamp":1617271388000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["On the mechanisms governing the critical current reduction in Nb3Sn Rutherford cables under transverse stress"],"prefix":"10.1038","volume":"11","author":[{"given":"Gianluca","family":"De Marzi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernardo","family":"Bordini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dario","family":"Baffari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,4,1]]},"reference":[{"key":"86563_CR1","doi-asserted-by":"publisher","first-page":"893","DOI":"10.3938\/jkps.69.893","volume":"69","author":"M Benedikt","year":"2016","unstructured":"Benedikt, M. & Zimmermann, F. 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