{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T01:16:00Z","timestamp":1782954960506,"version":"3.54.5"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T00:00:00Z","timestamp":1619740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T00:00:00Z","timestamp":1619740800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100012397","name":"Army Medical University","doi-asserted-by":"publisher","award":["410301060196"],"award-info":[{"award-number":["410301060196"]}],"id":[{"id":"10.13039\/501100012397","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012397","name":"Army Medical University","doi-asserted-by":"publisher","award":["410301060194"],"award-info":[{"award-number":["410301060194"]}],"id":[{"id":"10.13039\/501100012397","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018610","name":"Innovation Program in Military Medicine of Chinese People\u2019s Liberation Army","doi-asserted-by":"publisher","award":["20QNPY005"],"award-info":[{"award-number":["20QNPY005"]}],"id":[{"id":"10.13039\/501100018610","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Burns are one of the most common injuries in daily life for all ages of population. This study was to investigate the epidemiology and outcomes among burn patients in one of the largest burn centers in the southwest of China. The study was performed at the Institute of Burn Research in the first affiliated with the Army Medical University (AMU). A total of 17,939 burn patients were included in this retrospective study. Information regarding burn epidemiology and outcomes in 17 years were collected, calculated and compared. The age ranged from 257\u00a0days to 95\u00a0years old. Scalding and flame were the two most common causes to burn injuries, comprising of 91.96% in total. Limbs, head\/face\/neck, and trunk were the most frequently occurred burn sites, with the number and the percent of 12,324 (68.70%), 7989 (44.53%), and 7771 (43.32%), respectively. The average total body surface area (TBSA) was 13.64\u2009\u00b1\u200916.83% (median 8%) with a range of 0.1\u2013100%. A total of 874 (4.9%) patients had TBSA\u2009&gt;\u200950%. The presence of a burn with an inhalation injury was confirmed in 543 patients (3.03%). The average LOS was 32.11\u2009\u00b1\u200965.72\u00a0days (median: 17\u00a0days). Eventually, the retrospective analysis resulted in the development of a burn management continuum used for developing strategies to prevent and manage severe burns. The annual number of burn injuries has kept decreasing, which was partially attributed to the increased awareness and education of burn prevention and the improved burn-preventative circumstances. However, the burn severity and the economic burden were still in a high level. And the gender difference and age difference should be considered when making individualized interventions and rehabilitative treatments.\n<\/jats:p>","DOI":"10.1038\/s41598-021-88507-x","type":"journal-article","created":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T10:04:45Z","timestamp":1619777085000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":29,"title":["Development of a framework for managing severe burns through a 17-year retrospective analysis of burn epidemiology and outcomes"],"prefix":"10.1038","volume":"11","author":[{"given":"Ling","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaochong","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jishu","family":"Xian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianmei","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuanji","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zonghua","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,4,30]]},"reference":[{"key":"88507_CR1","doi-asserted-by":"publisher","first-page":"46066","DOI":"10.1038\/srep46066","volume":"7","author":"H Li","year":"2017","unstructured":"Li, H. et al. Epidemiology and outcome analysis of 6325 burn patients: A five-year retrospective study in a major burn center in Southwest China. Sci. Rep. 7, 46066. https:\/\/doi.org\/10.1038\/srep46066 (2017).","journal-title":"Sci. Rep."},{"key":"88507_CR2","doi-asserted-by":"publisher","first-page":"R188","DOI":"10.1186\/cc9300","volume":"14","author":"N Brusselaers","year":"2010","unstructured":"Brusselaers, N., Monstrey, S., Vogelaers, D., Hoste, E. & Blot, S. Severe burn injury in Europe: A systematic review of the incidence, etiology, morbidity, and mortality. Crit. Care 14, R188. https:\/\/doi.org\/10.1186\/cc9300 (2010).","journal-title":"Crit. Care"},{"key":"88507_CR3","unstructured":"American Burn Association. Burn Incident Fact Sheet (2016). http:\/\/ameriburn.org\/who-we-are\/media\/burn-incidence-fact-sheet\/. Accessed 19 April 2021."},{"key":"88507_CR4","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.burns.2016.08.013","volume":"43","author":"C Smolle","year":"2017","unstructured":"Smolle, C. et al. Recent trends in burn epidemiology worldwide: A systematic review. Burns 43, 249\u2013257. https:\/\/doi.org\/10.1016\/j.burns.2016.08.013 (2017).","journal-title":"Burns"},{"key":"88507_CR5","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1136\/bmj.329.7462.391","volume":"329","author":"SA Wiechman","year":"2004","unstructured":"Wiechman, S. A. & Patterson, D. R. ABC of burns. Psychosocial aspects of burn injuries. BMJ 329, 391\u2013393. https:\/\/doi.org\/10.1136\/bmj.329.7462.391 (2004).","journal-title":"BMJ"},{"key":"88507_CR6","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1186\/s41038-017-0075-y","volume":"5","author":"S Tripathee","year":"2017","unstructured":"Tripathee, S. & Basnet, S. J. Epidemiology of burn injuries in Nepal: A systemic review. Burns Trauma 5, 10. https:\/\/doi.org\/10.1186\/s41038-017-0075-y (2017).","journal-title":"Burns Trauma"},{"key":"88507_CR7","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1186\/s12916-015-0286-7","volume":"13","author":"T Boerma","year":"2015","unstructured":"Boerma, T. & Mathers, C. D. The World Health Organization and global health estimates: Improving collaboration and capacity. BMC Med. 13, 50. https:\/\/doi.org\/10.1186\/s12916-015-0286-7 (2015).","journal-title":"BMC Med."},{"key":"88507_CR8","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1093\/pubmed\/fds102","volume":"35","author":"A Golshan","year":"2013","unstructured":"Golshan, A., Patel, C. & Hyder, A. A. A systematic review of the epidemiology of unintentional burn injuries in South Asia. J. Public Health (Oxf.) 35, 384\u2013396. https:\/\/doi.org\/10.1093\/pubmed\/fds102 (2013).","journal-title":"J. Public Health (Oxf.)"},{"key":"88507_CR9","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/j.burns.2007.08.009","volume":"34","author":"MD Peck","year":"2008","unstructured":"Peck, M. D. et al. Burns and injuries from non-electric-appliance fires in low- and middle-income countries. Part II. A strategy for intervention using the Haddon matrix. Burns 34, 312\u2013319. https:\/\/doi.org\/10.1016\/j.burns.2007.08.009 (2008).","journal-title":"Burns"},{"key":"88507_CR10","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1542\/peds.2007-1567","volume":"122","author":"L Kai-Yang","year":"2008","unstructured":"Kai-Yang, L. et al. Epidemiology of pediatric burns requiring hospitalization in China: A literature review of retrospective studies. Pediatrics 122, 132\u2013142. https:\/\/doi.org\/10.1542\/peds.2007-1567 (2008).","journal-title":"Pediatrics"},{"key":"88507_CR11","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1186\/s12887-016-0686-7","volume":"16","author":"S Wang","year":"2016","unstructured":"Wang, S. et al. Epidemiology of burns in pediatric patients of Beijing City. BMC Pediatr. 16, 166. https:\/\/doi.org\/10.1186\/s12887-016-0686-7 (2016).","journal-title":"BMC Pediatr."},{"key":"88507_CR12","doi-asserted-by":"publisher","first-page":"1306","DOI":"10.1016\/j.burns.2017.03.004","volume":"43","author":"H Li","year":"2017","unstructured":"Li, H. et al. Epidemiology of pediatric burns in southwest China from 2011 to 2015. Burns 43, 1306\u20131317. https:\/\/doi.org\/10.1016\/j.burns.2017.03.004 (2017).","journal-title":"Burns"},{"key":"88507_CR13","doi-asserted-by":"publisher","first-page":"1111","DOI":"10.1016\/j.burns.2016.02.010","volume":"42","author":"A Tan","year":"2016","unstructured":"Tan, A. et al. Smoke inhalation increases intensive care requirements and morbidity in paediatric burns. Burns 42, 1111\u20131115. https:\/\/doi.org\/10.1016\/j.burns.2016.02.010 (2016).","journal-title":"Burns"},{"key":"88507_CR14","doi-asserted-by":"publisher","first-page":"R183","DOI":"10.1186\/cc8170","volume":"13","author":"FN Williams","year":"2009","unstructured":"Williams, F. N. et al. The leading causes of death after burn injury in a single pediatric burn center. Crit. Care 13, R183. https:\/\/doi.org\/10.1186\/cc8170 (2009).","journal-title":"Crit. Care"},{"key":"88507_CR15","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1016\/j.burns.2015.12.004","volume":"42","author":"C Ye","year":"2016","unstructured":"Ye, C. et al. Ten-year epidemiology of chemical burns in western Zhejiang Province, China. Burns 42, 668\u2013674. https:\/\/doi.org\/10.1016\/j.burns.2015.12.004 (2016).","journal-title":"Burns"},{"key":"88507_CR16","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1016\/j.jss.2017.02.032","volume":"214","author":"H Li","year":"2017","unstructured":"Li, H. et al. Wound management and outcome of 595 electrical burns in a major burn center. J. Surg. Res. 214, 182\u2013189. https:\/\/doi.org\/10.1016\/j.jss.2017.02.032 (2017).","journal-title":"J. Surg. Res."},{"key":"88507_CR17","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/s41038-017-0082-z","volume":"5","author":"H Li","year":"2017","unstructured":"Li, H. et al. The progress of Chinese burn medicine from the Third Military Medical University-in memory of its pioneer, Professor Li Ao. Burns Trauma 5, 16. https:\/\/doi.org\/10.1186\/s41038-017-0082-z (2017).","journal-title":"Burns Trauma"},{"key":"88507_CR18","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/j.burns.2004.10.028","volume":"31","author":"K Peleg","year":"2005","unstructured":"Peleg, K., Goldman, S. & Sikron, F. Burn prevention programs for children: Do they reduce burn-related hospitalizations? Burns 31, 347\u2013350. https:\/\/doi.org\/10.1016\/j.burns.2004.10.028 (2005).","journal-title":"Burns"},{"key":"88507_CR19","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/j.burns.2014.05.004","volume":"41","author":"DK Seo","year":"2015","unstructured":"Seo, D. K. et al. Epidemiological trends and risk factors in major burns patients in South Korea: A 10-year experience. Burns 41, 181\u2013187. https:\/\/doi.org\/10.1016\/j.burns.2014.05.004 (2015).","journal-title":"Burns"},{"key":"88507_CR20","doi-asserted-by":"publisher","first-page":"105","DOI":"10.5505\/tjtes.2012.45538","volume":"18","author":"I Ciftci","year":"2012","unstructured":"Ciftci, I., Arslan, K., Altunbas, Z., Kara, F. & Yilmaz, H. Epidemiologic evaluation of patients with major burns and recommendations for burn prevention. Ulus Travma Acil Cerrahi Derg 18, 105\u2013110 (2012).","journal-title":"Ulus Travma Acil Cerrahi Derg"},{"key":"88507_CR21","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1016\/j.burns.2012.07.011","volume":"39","author":"T Iqbal","year":"2013","unstructured":"Iqbal, T., Saaiq, M. & Ali, Z. Epidemiology and outcome of burns: Early experience at the country\u2019s first national burns centre. Burns 39, 358\u2013362. https:\/\/doi.org\/10.1016\/j.burns.2012.07.011 (2013).","journal-title":"Burns"},{"key":"88507_CR22","first-page":"263","volume":"104","author":"J Yates","year":"2011","unstructured":"Yates, J., McKay, M. & Nicholson, A. J. Patterns of scald injuries in children\u2013has anything changed? Iran. Med. J. 104, 263\u2013265 (2011).","journal-title":"Iran. Med. J."},{"key":"88507_CR23","doi-asserted-by":"publisher","first-page":"439","DOI":"10.1097\/01.BCR.0000226250.26567.4C","volume":"27","author":"B Arnoldo","year":"2006","unstructured":"Arnoldo, B., Klein, M. & Gibran, N. S. Practice guidelines for the management of electrical injuries. J. Burn Care Res. 27, 439\u2013447. https:\/\/doi.org\/10.1097\/01.BCR.0000226250.26567.4C (2006).","journal-title":"J. Burn Care Res."},{"key":"88507_CR24","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/j.socscimed.2017.11.014","volume":"195","author":"YY Chen","year":"2017","unstructured":"Chen, Y. Y., Chen, M., Lui, C. S. M. & Yip, P. S. F. Female labour force participation and suicide rates in the world. Soc. Sci. Med. 195, 61\u201367. https:\/\/doi.org\/10.1016\/j.socscimed.2017.11.014 (2017).","journal-title":"Soc. Sci. Med."},{"key":"88507_CR25","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1016\/S0140-6736(11)61345-7","volume":"379","author":"R Kraft","year":"2012","unstructured":"Kraft, R. et al. Burn size and survival probability in paediatric patients in modern burn care: A prospective observational cohort study. Lancet 379, 1013\u20131021. https:\/\/doi.org\/10.1016\/S0140-6736(11)61345-7 (2012).","journal-title":"Lancet"},{"key":"88507_CR26","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1097\/TA.0b013e3181c453b3","volume":"68","author":"T Osler","year":"2010","unstructured":"Osler, T., Glance, L. G. & Hosmer, D. W. Simplified estimates of the probability of death after burn injuries: Extending and updating the baux score. J. Trauma 68, 690\u2013697. https:\/\/doi.org\/10.1097\/TA.0b013e3181c453b3 (2010).","journal-title":"J. Trauma"},{"key":"88507_CR27","doi-asserted-by":"publisher","first-page":"1048","DOI":"10.1016\/j.burns.2013.05.001","volume":"39","author":"AE Berndtson","year":"2013","unstructured":"Berndtson, A. E., Sen, S., Greenhalgh, D. G. & Palmieri, T. L. Estimating severity of burn in children: Pediatric risk of mortality (PRISM) score versus Abbreviated Burn Severity Index (ABSI). Burns 39, 1048\u20131053. https:\/\/doi.org\/10.1016\/j.burns.2013.05.001 (2013).","journal-title":"Burns"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-021-88507-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-021-88507-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-021-88507-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,3]],"date-time":"2022-12-03T07:31:29Z","timestamp":1670052689000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-021-88507-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,30]]},"references-count":27,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,12]]}},"alternative-id":["88507"],"URL":"https:\/\/doi.org\/10.1038\/s41598-021-88507-x","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,30]]},"assertion":[{"value":"12 January 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 April 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 April 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"9374"}}