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However, little is known about the factors associated with its progression. We investigated the characteristic of myopic eyes with progressive temporal VF defects. This retrospective, observational study included a total of 116 eyes: 39 eyes with temporal VFDs and an axial length greater than 24.5\u00a0mm, 77 eyes with typical glaucomatous VFDs who were followed up more than 5\u00a0years. VF progression was evaluated with Trend-based global progression analysis. In the temporal VFD group, the greater tilt ratios, the higher prevalence of \u03b2-zone peripapillary atrophy (\u03b2-PPA), the substantial increase in \u03b2-PPA were found, compared to the typical glaucomatous VFD groups (all <jats:italic>P<\/jats:italic>-values\u2009\u2264\u20090.001). The temporal VFD group had the slower progression than the typical glaucomatous VFD group on trend-based GPA (<jats:italic>P<\/jats:italic>\u2009=\u20090.047). In the multivariate linear regression analysis, the change of \u03b2-PPA area over years was related to temporal VFD progression (B, \u2212\u20090.000088, <jats:italic>P<\/jats:italic>\u2009=\u20090.003). In conclusion, myopic eyes with the temporal VFD, which come with growing \u03b2-PPA area, should be monitored with extra caution.<\/jats:p>","DOI":"10.1038\/s41598-021-88832-1","type":"journal-article","created":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T10:04:45Z","timestamp":1619777085000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Characteristics of progressive temporal visual field defects in patients with myopia"],"prefix":"10.1038","volume":"11","author":[{"given":"Jiyun","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chan Kee","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoung In","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,4,30]]},"reference":[{"issue":"5","key":"88832_CR1","doi-asserted-by":"publisher","first-page":"1036","DOI":"10.1016\/j.ophtha.2016.01.006","volume":"123","author":"BA Holden","year":"2016","unstructured":"Holden, B. 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