{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T13:07:30Z","timestamp":1787663250880,"version":"build-2736575974"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,5,24]],"date-time":"2021-05-24T00:00:00Z","timestamp":1621814400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,5,24]],"date-time":"2021-05-24T00:00:00Z","timestamp":1621814400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We assessed the discontinuation rate and the reason for discontinuation of common contraceptives used by reproductive-aged Thai women. We recruited 1880 women aged 18\u201345 years from the Family Planning Clinic of the Chulalongkorn Hospital in Bangkok. The participants were followed at three, six and twelve months. A Cox proportional hazards model was used to determine personal risks of discontinuing contraceptives. The incidence rate for discontinuation of combined oral contraceptive pills (COCs), depot medroxyprogesterone acetate (DMPA), copper intrauterine device (IUD), and contraceptive implant(s) were 21.3, 9.2, 4.4, and 2.3\/100 person-years, respectively. Most of the women who discontinued (185\/222) discontinued contraceptives due to side effects. Compared to contraceptive implant users, the adjusted hazard ratios (aHRs) [95% confidence intervals (CIs)] of discontinuing COCs, DMPA, and the copper IUD were 9.6 (4.3\u201321.8), 4.2 (1.8\u201310.0), and 2.2 (0.8\u20135.9), respectively. Lower income, higher parity, history of miscarriage, and history of abortion were independent predictors of contraceptive discontinuation in a multivariable model.<\/jats:p>","DOI":"10.1038\/s41598-021-90373-6","type":"journal-article","created":{"date-parts":[[2021,5,24]],"date-time":"2021-05-24T10:03:09Z","timestamp":1621850589000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Discontinuation rates of different contraceptive methods in Thai women up to 1-year after method initiation"],"prefix":"10.1038","volume":"11","author":[{"given":"Unnop","family":"Jaisamrarn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monchai","family":"Santipap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somsook","family":"Santibenchakul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,5,24]]},"reference":[{"key":"90373_CR1","doi-asserted-by":"publisher","first-page":"43","DOI":"10.2307\/2948087","volume":"8","author":"A Rosenfield","year":"1982","unstructured":"Rosenfield, A., Bennett, A., Varakamin, S. & Lauro, D. Thailand\u2019s family planning program: An Asian sucess story. Int. Fam. Plan. Perspect. 8, 43\u201351 (1982).","journal-title":"Int. Fam. Plan. Perspect."},{"key":"90373_CR2","unstructured":"National Statistical Office Thailand. Thailand Multiple Indicator Cluster Survey 2019, Survey Findings Report. (National Statistical Office of Thailand, 2020). https:\/\/www.unicef.org\/thailand\/media\/5146\/file\/Multiple%20Indicator%20Cluster%20Survey%202019.pdf."},{"key":"90373_CR3","unstructured":"The World Bank. Contraceptive prevalence, any methods (% of women ages 15\u201349)\u2014Thailand. https:\/\/data.worldbank.org\/indicator\/SP.DYN.CONM.ZS?locations=TH (2019).\nAccessed May 1  (2021)"},{"key":"90373_CR4","unstructured":"The World Bank. Fertility rate, total (births per woman)\u2014Thailand. https:\/\/data.worldbank.org\/indicator\/SP.DYN.TFRT.IN?locations=TH (2019). Accessed May 1  (2021)"},{"key":"90373_CR5","unstructured":"Department of Health, Ministry of Public Health, Thailand. Abortion surveillance, thailand 2020. https:\/\/rh.anamai.moph.go.th\/th\/infographic\/2313 (2020) Accessed May 1  (2021)"},{"key":"90373_CR6","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1007\/s10995-016-2237-0","volume":"21","author":"JA Hall","year":"2017","unstructured":"Hall, J. A., Benton, L., Copas, A. & Stephenson, J. Pregnancy intention and pregnancy outcome: Systematic review and meta-analysis. Matern. Child. Health J. 21, 670\u2013704. https:\/\/doi.org\/10.1007\/s10995-016-2237-0 (2017).","journal-title":"Matern. Child. Health J."},{"key":"90373_CR7","unstructured":"Sonfield, A., Hasstedt, K. & Benson, G. R. In Moving Forward: Family Planning in the Era of Health Reform. https:\/\/www.guttmacher.org\/report\/moving-forward-family-planning-era-health-reform (2014). Accessed December 1 (2020)"},{"key":"90373_CR8","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1016\/j.contraception.2019.06.007","volume":"100","author":"G Lazenby","year":"2019","unstructured":"Lazenby, G., Francis, E., Brzozowski, N., Rucker, L. & Dempsey, A. Postpartum LARC discontinuation and short interval pregnancies among women with HIV: A retrospective 9-year cohort study in South Carolina. Contraception 100, 279\u2013282. https:\/\/doi.org\/10.1016\/j.contraception.2019.06.007 (2019).","journal-title":"Contraception"},{"key":"90373_CR9","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.jadohealth.2019.02.020","volume":"65","author":"R Cohen","year":"2019","unstructured":"Cohen, R., Sheeder, J. & Teal, S. B. Predictors of discontinuation of long-acting reversible contraception before 30 months of use by adolescents and young women. J. Adolesc. 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Factors associated with the discontinuation of modern methods of contraception in the low income areas of Sukh Initiative Karachi: A community-based case control study. PLoS One. 14, e0218952. https:\/\/doi.org\/10.1371\/journal.pone.0218952 (2019).","journal-title":"PLoS One."},{"key":"90373_CR12","doi-asserted-by":"publisher","first-page":"662e1-8","DOI":"10.1016\/j.ajog.2015.08.001","volume":"213","author":"JT Diedrich","year":"2015","unstructured":"Diedrich, J. T., Zhao, Q., Madden, T., Secura, G. M. & Peipert, J. F. Three-year continuation of reversible contraception. Am. J. Obstet. Gynecol. 213, 662e1-8. https:\/\/doi.org\/10.1016\/j.ajog.2015.08.001 (2015).","journal-title":"Am. J. Obstet. Gynecol."},{"key":"90373_CR13","unstructured":"Sappan, R., Sothornwit, J., Wattanakamolchai, P. & Werawatakul, Y. Discontinuation of contraceptive implants within 12 months of use. Thai J. Obstet. Gynaecol. https:\/\/he02.tci-thaijo.org\/index.php\/tjog\/article\/view\/226895 (2021). 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