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A retrospective chart of all endophthalmitis patients diagnosed between September 2001 and August 2011 was reviewed. Only endophthalmitis cases with previous corneal or scleral infection were included in the study. The patients were followed until losing vision or eyeball, becoming phthisis, or the end of 2018. Eighty-seven patients with KSE were identified, all unilateral. The mean age was 56.4\u2009\u00b1\u200921.4\u00a0years. There was a slight male predilection (55 patients, 63.2%). The mean follow-up time was 50\u2009\u00b1\u2009149\u00a0weeks. The causative pathogens were identified in 35 patients (40.2%), with the highest frequency being bacteria. The most common bacterium was <jats:italic>Pseudomonas aeruginosa<\/jats:italic> (n\u2009=\u200913), and the most common fungus was <jats:italic>Aspergillus <\/jats:italic>sp. (n\u2009=\u20095). Fifteen patients achieved (17.2%) final visual acuity (VA) of hand motion or better after treatment. Eyeball removal was performed in 61 (70.1%) patients. From multivariate analysis, the only prognostic factor for poor final VA (worse than hand motion, HM) was poor VA (worse than HM) at the initial visit (relative risk 1.97, 95% confidence interval 1.15\u20133.36, p = 0.013). KSE is uncommon but has a devastating outcome. We found that the patient\u2019s initial VA was the only predictor for their final vision. <jats:italic>P. aeruginosa<\/jats:italic> was the most common identifiable organism in this study. However, several fungal infections were recognised. These findings should raise awareness for treatment of KSE in the tropics.<\/jats:p>","DOI":"10.1038\/s41598-021-90815-1","type":"journal-article","created":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T10:16:36Z","timestamp":1622110596000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Epidemiology of keratitis\/scleritis-related endophthalmitis in a university hospital in Thailand"],"prefix":"10.1038","volume":"11","author":[{"given":"Dhanach","family":"Dhirachaikulpanich","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunravitch","family":"Soraprajum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sutasinee","family":"Boonsopon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Warinyupa","family":"Pinitpuwadol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Preeyachan","family":"Lourthai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noppakhun","family":"Punyayingyong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nattaporn","family":"Tesavibul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pitipol","family":"Choopong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,5,27]]},"reference":[{"key":"90815_CR1","doi-asserted-by":"publisher","first-page":"28100","DOI":"10.1038\/srep28100","volume":"6","author":"X Lu","year":"2016","unstructured":"Lu, X. et al. 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