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Overall, data of 79 eyes (79 patients; 50 men; mean age, 68.0\u00a0years) up to postoperative 24\u00a0months were analyzed. Their mean intraocular pressure (IOP) was 20.4\u2009\u00b1\u20096.0\u00a0mmHg at baseline. Forty-two eyes (53.2%) achieved an IOP\u2009&lt;\u200915\u00a0mmHg and\u2009\u2265\u200920% reduction from baseline without additional treatments. Phakic eyes had a better survival probability than pseudophakic eyes after adjusting for age, sex, baseline IOP, best-corrected visual acuity, and eye drop score (hazard ratio 3.096; 95% confidence interval [95% CI] 1.367\u20137.013; P\u2009=\u20090.007). Phakic eyes treated with combined Trabectome and cataract surgeries (mean survival time, 22.250\u00a0months; 95% CI 17.606\u201326.894) had a better survival probability than pseudophakic eyes treated with Trabectome surgery only (mean survival time, 12.111\u00a0months; 95% CI 8.716\u201315.506; P\u2009=\u20090.009) after the adjustment. Among the eyes treated with Trabectome surgery only, phakic eyes required significantly less additional treatments than pseudophakic eyes (P\u2009=\u20090.04). Trabectome surgery may be indicated for phakic eyes with POAG in addition to eye-drop therapy.<\/jats:p>","DOI":"10.1038\/s41598-021-93711-w","type":"journal-article","created":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T10:03:06Z","timestamp":1626084186000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Factors associated with achieving intraocular pressure lower than 15\u00a0mmHg by Trabectome surgery in primary open-angle glaucoma"],"prefix":"10.1038","volume":"11","author":[{"given":"Kentaro","family":"Nakamura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rio","family":"Honda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoichi","family":"Soeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norihiro","family":"Nagai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuaki","family":"Kadonosono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4797-5705","authenticated-orcid":false,"given":"Yoko","family":"Ozawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,7,12]]},"reference":[{"key":"93711_CR1","doi-asserted-by":"publisher","first-page":"2183","DOI":"10.1016\/S0140-6736(17)31469-1","volume":"390","author":"JB Jonas","year":"2017","unstructured":"Jonas, J. 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