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The presence of the paravascular retinal abnormalities was determined in the images obtained by a ultra-widefield OCT (UWF OCT) instrument with an image field of 23\u2009\u00d7\u200920\u00a0mm. The results showed that a partial PVD was detected in 15 (21%) of the HM patients, and the number increased significantly with increasing age (<jats:italic>P<\/jats:italic>\u2009=\u20090.02). PVDs of any type were not found in the non-HM eyes. The number of microvascular folds also increased with age in the HM patients (<jats:italic>P<\/jats:italic>\u2009=\u20090.03). Medium-reflective columnar tissues were present between the detached vitreous and inner retinal surface in 4 (5%) eyes of the HM patients. Myopic RS was found in 3 (4%) HM patients in the paravascular area but not in the macular area. These results suggest that early partial PVD may play a role in pathological and proliferative vitreous changes of HM eyes. An intense vitreoretinal traction with bridging tissues may cause the various paravascular retinal abnormalities. In HM eyes, paravascular RS is already present at an early age which may progress to macular RS with aging.<\/jats:p>","DOI":"10.1038\/s41598-021-96783-w","type":"journal-article","created":{"date-parts":[[2021,8,30]],"date-time":"2021-08-30T10:03:21Z","timestamp":1630317801000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Posterior vitreous detachment and paravascular retinoschisis in highly myopic young patients detected by ultra-widefield OCT"],"prefix":"10.1038","volume":"11","author":[{"given":"Hiroyuki","family":"Takahashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriko","family":"Nakao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kosei","family":"Shinohara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keigo","family":"Sugisawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kengo","family":"Uramoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae","family":"Igarashi-Yokoi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoko","family":"Ohno-Matsui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,8,30]]},"reference":[{"key":"96783_CR1","doi-asserted-by":"publisher","first-page":"1384","DOI":"10.1016\/S0161-6420(93)31471-5","volume":"100","author":"J Akiba","year":"1993","unstructured":"Akiba, J. 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