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Observational, analytical study with healthy control group, volunteers. We recruited patients from 0 to 18\u00a0years old who were candidates for liver transplantation and patients after six months of liver transplantation performed for BA from January 1997 to August 2015 at Children\u2019s Institute of S\u00e3o Paulo University Medical School. The patients were submitted to a complete conventional echocardiographic study. After that, the images were captured for global longitudinal strain (GLS). A blood sample was collected for brain natriuretic peptide (BNP) level. Ejection fraction obtained by Simpson\u2019s method was significantly higher in the hepatic pre-transplantation group (p\u2009&lt;\u20090.001), as well as left atrial size (p\u2009&lt;\u20090.001) and left ventricle size (p\u2009=\u20090.039). The left ventricular mass index was significantly higher in pre-transplantation group (p\u2009&lt;\u20090.001). The left atrium volume (p\u2009=\u20090.008) and the left ventricular mass index (p t\u2009=\u20090.035) were higher in the post-transplant group. It was observed that the lower the BNP, the lower\/more negative the GLS in the post-transplant group (p\u2009=\u20090.038 and r\u2009=\u20090.427). Significant reduction in the overall longitudinal <jats:italic>strain<\/jats:italic> of the left ventricle was detected before (p\u2009=\u20090.01) and after liver transplantation (p\u2009=\u20090.019). A subclinical left ventricular systolic dysfunction was evidenced by two-dimensional speckle tracking technique before and after liver transplantation, even when compared to normal values of the last pediatric meta-analysis.<\/jats:p>","DOI":"10.1038\/s41598-021-97096-8","type":"journal-article","created":{"date-parts":[[2021,9,8]],"date-time":"2021-09-08T10:02:46Z","timestamp":1631095366000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Evaluation of ventricular systolic function by speckle tracking technique in patients with biliary atresia before and after liver transplantation"],"prefix":"10.1038","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6417-1744","authenticated-orcid":false,"given":"M\u00e1rcio Miranda","family":"Brito","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena Thie","family":"Miyatani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo Renato","family":"de Alencar Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Cristina Aoun","family":"Tannuri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uenis","family":"Tannuri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,9,8]]},"reference":[{"key":"97096_CR1","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.jacc.2011.03.026","volume":"58","author":"Z Raval","year":"2011","unstructured":"Raval, Z. et al. 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