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There is a possible interaction between prenatal exposition to sex hormone and thyroid functions in the adulthood. The study included 175 adults investigated in \u0141\u00f3d\u017a in the central Poland. It consisted of two main parts: a survey including questions about occurrence of thyroid gland dysfunction and anthropometric measurements (body mass and height and length of the second and fourth finger, waist and hip circumferences). The women who had thyroid disease had higher 2D:4D digit ratio (left hand) (mean\u2009=\u20091.004; SD\u2009=\u20090.036) than healthy ones (mean\u2009=\u20090.989; SD\u2009=\u20090.030) (t\u2009=\u2009\u2212\u00a02105; <jats:italic>p<\/jats:italic>\u2009=\u20090.038; d\u2009=\u20090.707). The association between thyroid diseases occurrence and prenatal steroid hormone exposition is noticed. 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