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Similarly, people who suffer from COVID-19 may query for their symptoms prior to accessing the medical system (or in lieu of it). To assist in the UK government\u2019s response to the COVID-19 pandemic we analyzed searches for relevant symptoms on the Bing web search engine from users in England to identify areas of the country where unexpected rises in relevant symptom searches occurred. These were reported weekly to the UK Health Security Agency to assist in their monitoring of the pandemic. Our analysis shows that searches for \u201cfever\u201d and \u201ccough\u201d were the most correlated with future case counts during the initial stages of the pandemic, with searches preceding case counts by up to 21 days. Unexpected rises in search patterns were predictive of anomalous rises in future case counts within a week, reaching an Area Under Curve of 0.82 during the initial phase of the pandemic, and later reducing due to changes in symptom presentation. Thus, analysis of regional searches for symptoms can provide an early indicator (of more than one week) of increases in COVID-19 case counts.<\/jats:p>","DOI":"10.1038\/s41598-022-06340-2","type":"journal-article","created":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T11:04:53Z","timestamp":1644577493000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Providing early indication of regional anomalies in COVID-19 case counts in England using search engine queries"],"prefix":"10.1038","volume":"12","author":[{"given":"Elad","family":"Yom-Tov","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasileios","family":"Lampos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Inns","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingemar J.","family":"Cox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Edelstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,2,11]]},"reference":[{"key":"6340_CR1","doi-asserted-by":"publisher","first-page":"e46","DOI":"10.1016\/S0140-6736(20)30463-3","volume":"395","author":"P Moss","year":"2020","unstructured":"Moss, P., Barlow, G., Easom, N., Lillie, P. & Samson, A. 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