{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T14:39:01Z","timestamp":1794062341600,"version":"4.8.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T00:00:00Z","timestamp":1646611200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T00:00:00Z","timestamp":1646611200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Haemostatic procedures such as preperitoneal pelvic packing (PPP), pelvic angiography (PA), and internal iliac artery ligation are used for haemorrhage control in pelvic fracture patients with haemodynamic instability. Pelvic external fixation (PEF) and pelvic binder (PB) are usually applied with haemostatic procedures to reduce the pelvic volume. This study aimed to compare the clinical outcomes between patients who underwent PEF and PB. Among 173 patients with pelvic fracture admitted to the emergency room of three regional trauma centres between January 2015 and December 2018, the electronic charts of haemodynamically unstable patients were retrospectively analysed. Among the 84 patients included in the analysis, 20 underwent PEF with or without PB, and 64 underwent only PB. There were significant differences in tile classification and laparotomy between the PEF and PB groups (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.023 and\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.032). PPP tended to be more frequently preformed in the PEF group (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.054), whereas PA tended to be more commonly performed in the PB group than in the PEF group (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.054). After propensity score matching to adjust for differences in patient characteristics and adjunct haemostatic procedure, there was no significant difference in 7-day, 30-day, and overall mortality rates between the PEF and PB groups (10.5% vs 21.1%,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.660, 21.1% vs 26.3%,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20091.000, and 26.3% vs 26.3%,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20091.000). Cox proportional hazard regression analysis and multivariate analysis for correction of covariates (age, lactate, and abdominal injury) showed that PEF was not an independent factor for 30-day mortality compared with PB (adjusted hazard ratio, 0.526; 95% confidence interval, 0.092\u20133.002;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.469). Among the volume reduction procedures performed with other haemostatic procedures in patients with pelvic fracture and haemodynamic instability, PEF did not significantly reduce the 30-day mortality rate compared to PB.\n                  <\/jats:p>","DOI":"10.1038\/s41598-022-07694-3","type":"journal-article","created":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T06:06:11Z","timestamp":1646633171000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Comparison between external fixation and pelvic binder in patients with pelvic fracture and haemodynamic instability who underwent various haemostatic procedures"],"prefix":"10.1038","volume":"12","author":[{"given":"Ji Young","family":"Jang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keum Soek","family":"Bae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung Hee","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gil Jae","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,3,7]]},"reference":[{"issue":"6","key":"7694_CR1","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1097\/00000658-200106000-00015","volume":"233","author":"WL Biffl","year":"2001","unstructured":"Biffl, W. L. et al. Evolution of a multidisciplinary clinical pathway for the management of unstable patients with pelvic fractures. Ann Surg. 233(6), 843\u2013850 (2001).","journal-title":"Ann Surg."},{"key":"7694_CR2","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/s13017-017-0117-6","volume":"12","author":"F Coccolini","year":"2017","unstructured":"Coccolini, F. et al. Pelvic trauma: WSES classification and guidelines. World J Emerg Surg. 12, 5 (2017).","journal-title":"World J Emerg Surg."},{"issue":"5","key":"7694_CR3","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1097\/TA.0000000000001034","volume":"80","author":"TW Costantini","year":"2016","unstructured":"Costantini, T. W. et al. Current management of hemorrhage from severe pelvic fractures: Results of an American Association for the Surgery of Trauma multi-institutional trial. J. Trauma Acute Care Surg. 80(5), 717\u2013723 (2016) (discussion 23-5).","journal-title":"J. Trauma Acute Care Surg."},{"issue":"4","key":"7694_CR4","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/j.injury.2008.12.006","volume":"40","author":"T Suzuki","year":"2009","unstructured":"Suzuki, T., Smith, W. R. & Moore, E. E. Pelvic packing or angiography: competitive or complementary?. Injury 40(4), 343\u2013353 (2009).","journal-title":"Injury"},{"issue":"2","key":"7694_CR5","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1097\/TA.0000000000001324","volume":"82","author":"CC Burlew","year":"2017","unstructured":"Burlew, C. C. et al. Preperitoneal pelvic packing reduces mortality in patients with life-threatening hemorrhage due to unstable pelvic fractures. J. Trauma Acute Care Surg. 82(2), 233\u2013242 (2017).","journal-title":"J. Trauma Acute Care Surg."},{"issue":"6","key":"7694_CR6","first-page":"1507","volume":"69","author":"J DuBose","year":"2010","unstructured":"DuBose, J. et al. Bilateral internal iliac artery ligation as a damage control approach in massive retroperitoneal bleeding after pelvic fracture. J. Trauma 69(6), 1507\u20131514 (2010).","journal-title":"J. Trauma"},{"issue":"3","key":"7694_CR7","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1097\/TA.0000000000001794","volume":"84","author":"A Pieper","year":"2018","unstructured":"Pieper, A. et al. Resuscitative endovascular balloon occlusion of the aorta for pelvic blunt trauma and life-threatening hemorrhage: a 20-year experience in a Level I trauma center. J. Trauma Acute Care Surg. 84(3), 449\u2013453 (2018).","journal-title":"J. Trauma Acute Care Surg."},{"issue":"11","key":"7694_CR8","doi-asserted-by":"publisher","first-page":"e0206991","DOI":"10.1371\/journal.pone.0206991","volume":"13","author":"H Shim","year":"2018","unstructured":"Shim, H. et al. Effectiveness and postoperative wound infection of preperitoneal pelvic packing in patients with hemodynamic instability caused by pelvic fracture. PLoS ONE 13(11), e0206991 (2018).","journal-title":"PLoS ONE"},{"issue":"6","key":"7694_CR9","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1001\/jamasurg.2019.0096","volume":"154","author":"B Joseph","year":"2019","unstructured":"Joseph, B. et al. Nationwide analysis of resuscitative endovascular balloon occlusion of the aorta in civilian trauma. JAMA Surg. 154(6), 500\u2013508 (2019).","journal-title":"JAMA Surg."},{"key":"7694_CR10","doi-asserted-by":"crossref","unstructured":"H\u00f6ch, A., Zeidler, S., Pieroh, P., Josten, C., Stuby, F. M., & Herath, S.C. Trends and efficacy of external emergency stabilization of pelvic ring fractures: results from the German Pelvic Trauma Registry. Eur. J. Trauma Emerg. Surg. (2019).","DOI":"10.1007\/s00068-019-01155-9"},{"issue":"5","key":"7694_CR11","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1016\/j.jamcollsurg.2007.01.059","volume":"204","author":"MA Croce","year":"2007","unstructured":"Croce, M. A., Magnotti, L. J., Savage, S. A., Wood, G. W. 2nd. & Fabian, T. C. Emergent pelvic fixation in patients with exsanguinating pelvic fractures. J. Am. Coll. Surg. 204(5), 935\u2013939 (2007) (discussion 40-2).","journal-title":"J. Am. Coll. Surg."},{"issue":"1","key":"7694_CR12","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1097\/TA.0000000000002316","volume":"87","author":"J Duchesne","year":"2019","unstructured":"Duchesne, J. et al. The effect of hemorrhage control adjuncts on outcome in severe pelvic fracture: A multi-institutional study. J. Trauma Acute Care Surg. 87(1), 117\u2013124 (2019).","journal-title":"J. Trauma Acute Care Surg."},{"issue":"4","key":"7694_CR13","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1016\/j.jamcollsurg.2010.12.020","volume":"212","author":"CC Burlew","year":"2011","unstructured":"Burlew, C. C. et al. Preperitoneal pelvic packing\/external fixation with secondary angioembolization: optimal care for life-threatening hemorrhage from unstable pelvic fractures. J. Am. Coll. Surg. 212(4), 628\u2013635 (2011) (discussion 35-7).","journal-title":"J. Am. Coll. Surg."},{"issue":"5","key":"7694_CR14","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1097\/TA.0000000000002618","volume":"88","author":"S Frassini","year":"2020","unstructured":"Frassini, S. et al. Extraperitoneal packing in unstable blunt pelvic trauma: a single-center study. J. Trauma Acute Care Surg. 88(5), 597\u2013606 (2020).","journal-title":"J. Trauma Acute Care Surg."},{"issue":"6","key":"7694_CR15","doi-asserted-by":"publisher","first-page":"1671","DOI":"10.1097\/TA.0b013e31824526a7","volume":"72","author":"ML Prasarn","year":"2012","unstructured":"Prasarn, M. L. et al. Comparison of external fixation versus the trauma pelvic orthotic device on unstable pelvic injuries: a cadaveric study of stability. J. Trauma Acute Care Surg. 72(6), 1671\u20131675 (2012).","journal-title":"J. Trauma Acute Care Surg."},{"issue":"1","key":"7694_CR16","doi-asserted-by":"publisher","first-page":"5106","DOI":"10.1038\/s41598-020-62027-6","volume":"10","author":"T Zingg","year":"2020","unstructured":"Zingg, T. et al. Prehospital use of pelvic circumferential compression devices in a physician-based emergency medical service: A 6-year retrospective cohort study. Sci. Rep. 10(1), 5106 (2020).","journal-title":"Sci. Rep."},{"issue":"1","key":"7694_CR17","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.injury.2019.08.001","volume":"51","author":"D McCreary","year":"2020","unstructured":"McCreary, D. et al. Haemodynamics as a determinant of need for pre-hospital application of a pelvic circumferential compression device in adult trauma patients. Injury 51(1), 4\u20139 (2020).","journal-title":"Injury"},{"key":"7694_CR18","unstructured":"ACS Tcoto. Advanced Trauma Life Support (ATLS) Student manual 10th ed. 97\u201398 (2018)."},{"issue":"5","key":"7694_CR19","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.1097\/TA.0000000000000609","volume":"78","author":"WL Biffl","year":"2015","unstructured":"Biffl, W. L., Fox, C. J. & Moore, E. E. The role of REBOA in the control of exsanguinating torso hemorrhage. J. Trauma Acute Care Surg. 78(5), 1054\u20131058 (2015).","journal-title":"J. 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Resuscitative endovascular balloon occlusion of the aorta and resuscitative thoracotomy in select patients with hemorrhagic shock: early results from the american association for the surgery of trauma\u2019s aortic occlusion in resuscitation for trauma and acute care surgery registry. J. Am. Coll. Surg. 226(5), 730\u2013740 (2018).","journal-title":"J. Am. Coll. Surg."},{"issue":"3","key":"7694_CR22","doi-asserted-by":"publisher","first-page":"144","DOI":"10.20408\/jti.2020.0051","volume":"33","author":"J Park","year":"2020","unstructured":"Park, J. et al. An Early experience of resuscitative endovascular balloon occlusion of the aorta (REBOA) in the Republic of Korea: a retrospective multicenter study. J. Trauma Inj. 33(3), 144\u2013152 (2020).","journal-title":"J. Trauma Inj."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-022-07694-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-022-07694-3","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-022-07694-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,24]],"date-time":"2022-11-24T18:46:48Z","timestamp":1669315608000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-022-07694-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,7]]},"references-count":22,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["7694"],"URL":"https:\/\/doi.org\/10.1038\/s41598-022-07694-3","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-774824\/v1","asserted-by":"object"}]},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,7]]},"assertion":[{"value":"2 August 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 February 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 March 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"3664"}}