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We have explored the efficacy of laundry sanitizers for inactivating coronaviruses and influenza viruses. Virucidal efficacy was tested using standardized suspension inactivation methods (EN 14476) or hard-surface inactivation methods (ASTM E1053-20) against SARS-CoV-2, human coronavirus 229E (HCoV 229E), influenza A virus (2009-H1N1 A\/Mexico), or influenza B virus (B\/Hong Kong). Efficacy was measured in terms of log<jats:sub>10<\/jats:sub> reduction in infectious virus titer, after 15\u00a0min contact time (suspension studies) or 5\u00a0min contact time (hard surface studies) at 20\u2009\u00b1\u20091\u00a0\u00b0C. In liquid suspension studies, laundry sanitizers containing <jats:italic>p<\/jats:italic>-chloro-<jats:italic>m<\/jats:italic>-xylenol (PCMX) or quaternary ammonium compounds (QAC) caused complete inactivation (\u2265\u20094 log<jats:sub>10<\/jats:sub>) of HCoV 229E and SARS-CoV-2 within 15\u00a0min contact time at 20\u2009\u00b1\u20091\u00a0\u00b0C. In hard surface studies, complete inactivation (\u2265\u20094 log<jats:sub>10<\/jats:sub>) of each coronavirus or influenza virus, including SARS-CoV-2, was observed following a 5-min contact time at 20\u2009\u00b1\u20091\u00a0\u00b0C. Respiratory viruses may remain infectious on clothing\/fabrics and environmental surfaces for hours to days. The use of a laundry sanitizer containing microbicidal actives may afford mitigation of the risk of contamination of surfaces during handling of the laundry and washing appliances (i.e., washer\/dryer or basin), adjacent surfaces, the waste water stream, and the hands of individuals handling clothes contaminated with SARS-CoV-2, influenza viruses, or other emerging enveloped viruses.<\/jats:p>","DOI":"10.1038\/s41598-022-08259-0","type":"journal-article","created":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T04:31:44Z","timestamp":1648528304000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Virucidal efficacy of laundry sanitizers against SARS-CoV-2 and other coronaviruses and influenza viruses"],"prefix":"10.1038","volume":"12","author":[{"given":"M.","family":"Khalid Ijaz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond W.","family":"Nims","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"McKinney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles P.","family":"Gerba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,3,28]]},"reference":[{"key":"8259_CR1","unstructured":"United States Centers for Disease Control and Prevention. 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