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As NAFLD increases, the need to incentivize health-seeking behaviors grows. No evidence-based interventions to address this gap exist. The aim of the study was to estimate the effect of providing increasing levels of diagnostic information on medical care-seeking in adults newly diagnosed with NAFLD. We randomly assigned adults with a sonographic diagnosis of NAFLD at a check-up unit in Mexico\u00a0to one of five groups.\u00a0All groups received medical consultation. A: no further interventions; B: received multimedia educational material (MEM); C: MEM\u2009+\u2009NAFLD-fibrosis-score (NFS); D: MEM\u2009+\u2009transient elastography (TE); E: MEM\u2009+\u2009NFS\u2009+\u2009TE. 1209 participants were\u00a0randomized, follow-up rate 91%; 82% male, BMI 30.5\u2009\u00b1\u20094\u00a0kg\/m<jats:sup>2<\/jats:sup>. There were no differences in the proportion of patients undergoing further diagnostic evaluation of liver fibrosis (A 0.4%, E 0.4%, P-for-trend\u2009=\u20090.269). Groups who received more information sought specialized medical care more frequently: A 22%, E 30% (P-for-trend\u2009=\u20090.047). A trend to receive treatment was also observed at higher levels of information: A 26.7%, E 36.3% (P-for-trend\u2009=\u20090.134). Increasing the amount of diagnostic information seemed to increase patient\u2019s health-seeking. Tailoring the communication of information obtained for diagnosis could help to increase health-seeking in chronic disease patients.<\/jats:p><jats:p>Trial registration: NCT01874249 (full date of first registration 11-06-2013).<\/jats:p>","DOI":"10.1038\/s41598-022-12295-1","type":"journal-article","created":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T10:02:54Z","timestamp":1652868174000},"update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Incremental levels of diagnostic information incentivize health-seeking in non-alcoholic fatty liver: a randomized clinical trial"],"prefix":"10.1038","volume":"12","clinical-trial-number":[{"clinical-trial-number":"nct01874249","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Norberto C.","family":"Chavez-Tapia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tonatiuh","family":"Barrientos-Gutierrez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leticia","family":"Torres-Ibarra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatriz","family":"Sanchez-Jim\u00e9nez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Juarez-Hernandez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha","family":"Ramos-Ostos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis F.","family":"Alva-Lopez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Misael","family":"Uribe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,5,18]]},"reference":[{"issue":"1","key":"12295_CR1","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/S2468-1253(16)30011-5","volume":"1","author":"VWS Wong","year":"2016","unstructured":"Wong, V. 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