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Nipah virus together with Ebola virus and SARS-CoV-2 are prominent examples. Since COVID-19 and the West African Ebola virus disease outbreak, different chemical disinfectants have been developed for preventing the direct spread of viruses and their efficacy has also been evaluated. However, there are currently no published efficacy studies for the chemical disinfection of Nipah virus. In this study, the virucidal efficacy of three disinfectants (Micro-Chem Plus detergent disinfectant cleaner, FWD and Medical EtOH) against Nipah virus was evaluated in quantitative suspension tests including. Our results showed that the\u2009&gt;\u20094 log reduction achieved for all products in inactivating Nipah virus in 15\u00a0s. Even, 19% ethanol was able to inactivate Nipah virus when applied for at least 8\u00a0min contact time. Comparative analysis displayed virucidal efficacy of each of the evaluated disinfectants against SARS-CoV-2, Ebola virus and Nipah virus, with only minor differences in working concentrations and contact times required for complete inactivation. We expect that our study can assist in decontamination in healthcare settings and high level biosafety laboratories and can be beneficial to control for emerging enveloped viruses.<\/jats:p>","DOI":"10.1038\/s41598-022-15228-0","type":"journal-article","created":{"date-parts":[[2022,7,5]],"date-time":"2022-07-05T15:51:09Z","timestamp":1657036269000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Evaluation and comparison of three virucidal agents on inactivation of Nipah virus"],"prefix":"10.1038","volume":"12","author":[{"given":"Yi","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuqi","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donglin","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiming","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,7,5]]},"reference":[{"issue":"5","key":"15228_CR1","doi-asserted-by":"publisher","first-page":"e1400253","DOI":"10.1126\/sciadv.1400253","volume":"1","author":"G Ceballos","year":"2015","unstructured":"Ceballos, G. et al. 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