{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T01:29:05Z","timestamp":1780450145487,"version":"3.54.1"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T00:00:00Z","timestamp":1658707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T00:00:00Z","timestamp":1658707200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"2019 Wakayama Medical Award for Young Researchers"},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["26462249"],"award-info":[{"award-number":["26462249"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["23390356"],"award-info":[{"award-number":["23390356"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","award":["23390172"],"award-info":[{"award-number":["23390172"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology,Japan","doi-asserted-by":"crossref","award":["21K09306"],"award-info":[{"award-number":["21K09306"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology,Japan","doi-asserted-by":"crossref","award":["24659666"],"award-info":[{"award-number":["24659666"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology,Japan","doi-asserted-by":"crossref","award":["23390357"],"award-info":[{"award-number":["23390357"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology,Japan","doi-asserted-by":"crossref","award":["19H05654"],"award-info":[{"award-number":["19H05654"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology,Japan","doi-asserted-by":"crossref","award":["08033011-00262"],"award-info":[{"award-number":["08033011-00262"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology,Japan","doi-asserted-by":"crossref","award":["22591639"],"award-info":[{"award-number":["22591639"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Japan Osteoporosis Society"},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["H23-Choujyu-002"],"award-info":[{"award-number":["H23-Choujyu-002"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["H17-Men-eki-009"],"award-info":[{"award-number":["H17-Men-eki-009"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["H25-Nanchitou (Men)-005"],"award-info":[{"award-number":["H25-Nanchitou (Men)-005"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["H20-Choujyu-009"],"award-info":[{"award-number":["H20-Choujyu-009"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Japanese Orthopedic Association"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The relationship between acetabular dysplasia and spino-pelvic alignment remains unclear. The aim of this study was to clarify the association between acetabular dysplasia and spino-pelvic alignment, based on a large-scale population-based cohort in Japan. From the third survey of the Research on Osteoarthritis\/Osteoporosis Against Disability (ROAD) study, 1,481 participants (491 men and 990 women; mean age, 65.3\u00a0years) were analyzed. Center-edge (CE) angle and spino-pelvic parameters (lumbar lordosis, LL; sacral slope, SS; pelvic tilt, PT; pelvic incidence, PI) were measured radiographically. Acetabular dysplasia was defined as a CE angle &lt;\u200920\u00b0, and associations between acetabular dysplasia and spino-pelvic parameters were assessed. The group with acetabular dysplasia had significantly higher age, higher percentage of female, higher SS and higher PI than the group without acetabular dysplasia in a univariate analysis. On the other hand, acetabular dysplasia was not significantly associated with spino-pelvic parameters in a multiple logistic regression analysis that include age, sex, SS and PI as explanatory variables; however, PI demonstrated a positive odds ratio (odds ratio, 1.02; 95% CI 1.00\u20131.04). In conclusion, acetabular dysplasia was not significantly associated with spino-pelvic parameters, but higher PI may be an associated factor for acetabular dysplasia.<\/jats:p>","DOI":"10.1038\/s41598-022-16865-1","type":"journal-article","created":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T20:02:56Z","timestamp":1658779376000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Association between acetabular dysplasia and sagittal spino-pelvic alignment in a population-based cohort in Japan"],"prefix":"10.1038","volume":"12","author":[{"given":"Teiji","family":"Harada","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Hashizume","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takaya","family":"Taniguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiko","family":"Iidaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiki","family":"Asai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Oka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeyuki","family":"Muraki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toru","family":"Akune","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Kawaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kozo","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Munehito","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sakae","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriko","family":"Yoshimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,7,25]]},"reference":[{"key":"16865_CR1","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1097\/00007632-198304000-00014","volume":"8","author":"CM Offierski","year":"1983","unstructured":"Offierski, C. M. & MacNab, I. Hip-spine syndrome. Spine 8, 316\u2013321. https:\/\/doi.org\/10.1097\/00007632-198304000-00014 (1983).","journal-title":"Spine"},{"key":"16865_CR2","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1097\/00003086-198612000-00004","volume":"203","author":"WH Harris","year":"1986","unstructured":"Harris, W. H. Etiology of osteoarthritis of the hip. Clin. Orthop. Relat. Res. 203, 20\u201333. https:\/\/doi.org\/10.1097\/00003086-198612000-00004 (1986).","journal-title":"Clin. Orthop. Relat. Res."},{"key":"16865_CR3","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1002\/art.20886","volume":"52","author":"M Reijman","year":"2005","unstructured":"Reijman, M., Hazes, J. M., Pols, H. A., Koes, B. W. & Bierma-Zeinstra, S. M. Acetabular dysplasia predicts incident osteoarthritis of the hip: the Rotterdam study. Arthritis Rheum. 52, 787\u2013793. https:\/\/doi.org\/10.1002\/art.20886 (2005).","journal-title":"Arthritis Rheum."},{"key":"16865_CR4","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1007\/s00776-011-0025-7","volume":"16","author":"S Jingushi","year":"2011","unstructured":"Jingushi, S. et al. Osteoarthritis hip joints in Japan: Involvement of acetabular dysplasia. J. Orthop. Sci. 16, 156\u2013164. https:\/\/doi.org\/10.1007\/s00776-011-0025-7 (2011).","journal-title":"J. Orthop. Sci."},{"key":"16865_CR5","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1007\/s00776-010-1507-8","volume":"15","author":"S Jingushi","year":"2010","unstructured":"Jingushi, S. et al. Multiinstitutional epidemiological study regarding osteoarthritis of the hip in Japan. J. Orthop. Sci. 15, 626\u2013631. https:\/\/doi.org\/10.1007\/s00776-010-1507-8 (2010).","journal-title":"J. Orthop. Sci."},{"key":"16865_CR6","doi-asserted-by":"publisher","first-page":"1495","DOI":"10.1007\/s00402-018-2992-z","volume":"138","author":"K Fukushima","year":"2018","unstructured":"Fukushima, K. et al. Relationship between spinal sagittal alignment and acetabular coverage: A patient-matched control study. Arch. Orthop. Trauma. Surg. 138, 1495\u20131499. https:\/\/doi.org\/10.1007\/s00402-018-2992-z (2018).","journal-title":"Arch. Orthop. Trauma. Surg."},{"key":"16865_CR7","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1186\/s13018-019-1382-8","volume":"14","author":"N Imai","year":"2019","unstructured":"Imai, N., Suzuki, H., Nozaki, A., Hirano, Y. & Endo, N. Correlation of tilt of the anterior pelvic plane angle with anatomical pelvic tilt and morphological configuration of the acetabulum in patients with developmental dysplasia of the hip: A cross-sectional study. J. Orthop. Surg. Res. 14, 323. https:\/\/doi.org\/10.1186\/s13018-019-1382-8 (2019).","journal-title":"J. Orthop. Surg. Res."},{"key":"16865_CR8","doi-asserted-by":"publisher","first-page":"2432","DOI":"10.1097\/01.brs.0000143671.67779.14","volume":"29","author":"Y Matsuyama","year":"2004","unstructured":"Matsuyama, Y. et al. Hip-spine syndrome: Total sagittal alignment of the spine and clinical symptoms in patients with bilateral congenital hip dislocation. Spine 29, 2432\u20132437. https:\/\/doi.org\/10.1097\/01.brs.0000143671.67779.14 (2004).","journal-title":"Spine"},{"key":"16865_CR9","doi-asserted-by":"publisher","first-page":"E816","DOI":"10.1097\/BRS.0b013e31815ce695","volume":"32","author":"T Okuda","year":"2007","unstructured":"Okuda, T. et al. Stage-specific sagittal spinopelvic alignment changes in osteoarthritis of the hip secondary to developmental hip dysplasia. Spine 32, E816\u2013E819. https:\/\/doi.org\/10.1097\/BRS.0b013e31815ce695 (2007).","journal-title":"Spine"},{"key":"16865_CR10","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1007\/s00774-009-0080-8","volume":"27","author":"N Yoshimura","year":"2009","unstructured":"Yoshimura, N. et al. Prevalence of knee osteoarthritis, lumbar spondylosis, and osteoporosis in Japanese men and women: The research on osteoarthritis\/osteoporosis against disability study. J. Bone Miner. Metab. 27, 620\u2013628. https:\/\/doi.org\/10.1007\/s00774-009-0080-8 (2009).","journal-title":"J. Bone Miner. Metab."},{"key":"16865_CR11","doi-asserted-by":"publisher","first-page":"988","DOI":"10.1093\/ije\/dyp276","volume":"39","author":"N Yoshimura","year":"2010","unstructured":"Yoshimura, N. et al. Cohort profile: Research on osteoarthritis\/Osteoporosis Against Disability study. Int. J. Epidemiol. 39, 988\u2013995. https:\/\/doi.org\/10.1093\/ije\/dyp276 (2010).","journal-title":"Int. J. Epidemiol."},{"key":"16865_CR12","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.joca.2015.07.017","volume":"24","author":"T Iidaka","year":"2016","unstructured":"Iidaka, T. et al. Prevalence of radiographic hip osteoarthritis and its association with hip pain in Japanese men and women: The ROAD study. Osteoarthr. Cartil. 24, 117\u2013123. https:\/\/doi.org\/10.1016\/j.joca.2015.07.017 (2016).","journal-title":"Osteoarthr. Cartil."},{"key":"16865_CR13","doi-asserted-by":"publisher","first-page":"2072","DOI":"10.1016\/j.joca.2017.08.008","volume":"25","author":"T Iidaka","year":"2017","unstructured":"Iidaka, T. et al. Radiographic measurements of the hip joint and their associations with hip pain in Japanese men and women: The Research on Osteoarthritis\/osteoporosis Against Disability (ROAD) study. Osteoarthr. Cartil. 25, 2072\u20132079. https:\/\/doi.org\/10.1016\/j.joca.2017.08.008 (2017).","journal-title":"Osteoarthr. Cartil."},{"key":"16865_CR14","first-page":"53","volume":"83","author":"G Wiberg","year":"1939","unstructured":"Wiberg, G. Studies on dysplastic acetabula and congenital subluxation of the hip joint: With special reference to the complication of osteoarthritis. Acta Chir. Scand. 83, 53\u201368 (1939).","journal-title":"Acta Chir. Scand."},{"key":"16865_CR15","doi-asserted-by":"publisher","first-page":"2224","DOI":"10.1097\/BRS.0b013e3181ee6bd4","volume":"35","author":"F Schwab","year":"2010","unstructured":"Schwab, F., Patel, A., Ungar, B., Farcy, J. P. & Lafage, V. Adult spinal deformity-postoperative standing imbalance: How much can you tolerate? An overview of key parameters in assessing alignment and planning corrective surgery. Spine 35, 2224\u20132231. https:\/\/doi.org\/10.1097\/BRS.0b013e3181ee6bd4 (2010).","journal-title":"Spine"},{"key":"16865_CR16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0178697","volume":"12","author":"Y Asai","year":"2017","unstructured":"Asai, Y. et al. Sagittal spino-pelvic alignment in adults: The Wakayama Spine Study. PLoS ONE 12, e0178697. https:\/\/doi.org\/10.1371\/journal.pone.0178697 (2017).","journal-title":"PLoS ONE"},{"key":"16865_CR17","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1097\/00007632-198811000-00019","volume":"13","author":"Y Takemitsu","year":"1988","unstructured":"Takemitsu, Y., Harada, Y., Iwahara, T., Miyamoto, M. & Miyatake, Y. Lumbar degenerative kyphosis. Clinical, radiological and epidemiological studies. Spine 13, 1317\u20131326. https:\/\/doi.org\/10.1097\/00007632-198811000-00019 (1988).","journal-title":"Spine"},{"key":"16865_CR18","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.1097\/01.brs.0000169446.69758.fa","volume":"30","author":"H Yoshimoto","year":"2005","unstructured":"Yoshimoto, H. et al. Spinopelvic alignment in patients with osteoarthrosis of the hip: A radiographic comparison to patients with low back pain. Spine 30, 1650\u20131657. https:\/\/doi.org\/10.1097\/01.brs.0000169446.69758.fa (2005).","journal-title":"Spine"},{"key":"16865_CR19","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1302\/2046-3758.52.2000552","volume":"5","author":"JJ Gebhart","year":"2016","unstructured":"Gebhart, J. J., Weinberg, D. S., Bohl, M. S. & Liu, R. W. Relationship between pelvic incidence and osteoarthritis of the hip. Bone Joint Res. 5, 66\u201372. https:\/\/doi.org\/10.1302\/2046-3758.52.2000552 (2016).","journal-title":"Bone Joint Res."},{"key":"16865_CR20","doi-asserted-by":"publisher","first-page":"2599","DOI":"10.1177\/0363546513500632","volume":"41","author":"A Henebry","year":"2013","unstructured":"Henebry, A. & Gaskill, T. The effect of pelvic tilt on radiographic markers of acetabular coverage. Am. J. Sports Med. 41, 2599\u20132603. https:\/\/doi.org\/10.1177\/0363546513500632 (2013).","journal-title":"Am. J. Sports Med."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-022-16865-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-022-16865-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-022-16865-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T04:34:36Z","timestamp":1669350876000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-022-16865-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7,25]]},"references-count":20,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["16865"],"URL":"https:\/\/doi.org\/10.1038\/s41598-022-16865-1","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7,25]]},"assertion":[{"value":"9 March 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 July 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 July 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"12686"}}