{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T17:46:25Z","timestamp":1790444785906,"version":"4.1.0"},"reference-count":103,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T00:00:00Z","timestamp":1659571200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T00:00:00Z","timestamp":1659571200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Anorexia Nervosa (AN) is an eating pathology characterized by restricted eating, body image distortions and impaired socio-cognitive abilities. Altered responses to affective touch\u2014a pleasant interoceptive stimulus hypothesised to involve activation of the C-Tactile (CT) system, may contribute to the aetiology and maintenance of this disorder. Here, we investigated whether third-party social touch vicarious ratings of different body sites at CT-optimal vs. non-CT optimal velocities differed in women with and recovered from AN (RAN) and healthy controls (HCs). Thirty-five HCs, 27 AN and 29 RAN provided pleasantness ratings for two different tasks designed to probe expectations of how touch is perceived by self (self-directed touch) vs. others (other-directed touch). Findings revealed that both clinical groups, compared to HCs, did not differ in their pleasantness ratings to touch for another but when evaluating touch for self, both clinical groups rated CT-optimal touch as less pleasant than HCs. These findings suggest that AN and RAN women demonstrate an atypical vicarious pleasantness response to affective touch involving self, but not others. Novel therapeutic approaches that help anorexics to better interpret or improve tolerance of affective tactile experiences involving the self may be an important addition to current standard treatments.<\/jats:p>","DOI":"10.1038\/s41598-022-17523-2","type":"journal-article","created":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T15:05:42Z","timestamp":1659625542000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Vicarious ratings of self vs. other-directed social touch in women with and recovered from Anorexia Nervosa"],"prefix":"10.1038","volume":"12","author":[{"given":"Ashleigh","family":"Bellard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Trotter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"McGlone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Cazzato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,8,4]]},"reference":[{"key":"17523_CR1","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1016\/j.psychres.2019.01.102","volume":"273","author":"F Beilharz","year":"2019","unstructured":"Beilharz, F. et al. Dysmorphic concern in anorexia nervosa: Implications for recovery. Psychiatry Res. 273, 657\u2013661 (2019).","journal-title":"Psychiatry Res."},{"issue":"3","key":"17523_CR2","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1007\/s00221-015-4498-z","volume":"234","author":"V Cazzato","year":"2016","unstructured":"Cazzato, V. et al. The effects of body exposure on self-body image and esthetic appreciation in anorexia nervosa. Exp. Brain Res. 234(3), 695\u2013709 (2016).","journal-title":"Exp. Brain Res."},{"issue":"4","key":"17523_CR3","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1111\/bjop.12057","volume":"105","author":"C Urgesi","year":"2014","unstructured":"Urgesi, C. et al. Impaired configural body processing in anorexia nervosa: Evidence from the body inversion effect. Br. J. Psychol. 105(4), 486\u2013508 (2014).","journal-title":"Br. J. Psychol."},{"key":"17523_CR4","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"2013","unstructured":"American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders 5th edn. (American Psychiatric Association, 2013).","edition":"5"},{"issue":"2","key":"17523_CR5","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1038\/npp.2015.174","volume":"41","author":"KL Kerr","year":"2016","unstructured":"Kerr, K. L. et al. Altered insula activity during visceral interoception in weight-restored patients with anorexia nervosa. Neuropsychopharmacology 41(2), 521\u2013528 (2016).","journal-title":"Neuropsychopharmacology"},{"issue":"3","key":"17523_CR6","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/j.psyneuen.2012.10.021","volume":"38","author":"P Monteleone","year":"2013","unstructured":"Monteleone, P. & Maj, M. Dysfunctions of leptin, ghrelin, BDNF and endocannabinoids in eating disorders: Beyond the homeostatic control of food intake. Psychoneuroendocrinology 38(3), 312\u2013330 (2013).","journal-title":"Psychoneuroendocrinology"},{"issue":"10","key":"17523_CR7","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1176\/appi.ajp.2013.11111745","volume":"170","author":"TA Oberndorfer","year":"2013","unstructured":"Oberndorfer, T. A. et al. Altered insula response to sweet taste processing after recovery from anorexia and bulimia nervosa. Am. J. Psychiatry 170(10), 1143\u20131151 (2013).","journal-title":"Am. J. Psychiatry"},{"issue":"3","key":"17523_CR8","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1016\/j.jpeds.2013.03.011","volume":"163","author":"ME Perez","year":"2013","unstructured":"Perez, M. E., Coley, B., Crandall, W., Di Lorenzo, C. & Bravender, T. Effect of nutritional rehabilitation on gastric motility and somatization in adolescents with anorexia. J. Pediatr. 163(3), 867\u2013872 (2013).","journal-title":"J. Pediatr."},{"issue":"1","key":"17523_CR9","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1002\/eat.22045","volume":"46","author":"IA Strigo","year":"2013","unstructured":"Strigo, I. A. et al. Altered insula activation during pain anticipation in individuals recovered from anorexia nervosa: Evidence of interoceptive dysregulation. Int. J. Eat. Disord. 46(1), 23\u201333 (2013).","journal-title":"Int. J. Eat. Disord."},{"issue":"8","key":"17523_CR10","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1038\/nrn2682","volume":"10","author":"WH Kaye","year":"2009","unstructured":"Kaye, W. H., Fudge, J. L. & Paulus, M. New insights into symptoms and neurocircuit function of anorexia nervosa. Nat. Rev. Neurosci. 10(8), 573\u2013584 (2009).","journal-title":"Nat. Rev. Neurosci."},{"issue":"1","key":"17523_CR11","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.jpsychores.2011.11.003","volume":"72","author":"JL Nandrino","year":"2012","unstructured":"Nandrino, J. L. et al. Cognitive and physiological dissociations in response to emotional pictures in patients with anorexia. J. Psychosom. Res. 72(1), 58\u201364 (2012).","journal-title":"J. Psychosom. Res."},{"issue":"1","key":"17523_CR12","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41398-018-0218-3","volume":"8","author":"A Bischoff-Grethe","year":"2018","unstructured":"Bischoff-Grethe, A. et al. Neural hypersensitivity to pleasant touch in women remitted from anorexia nervosa. Transl. Psychiatry 8(1), 1\u201313 (2018).","journal-title":"Transl. Psychiatry"},{"issue":"1","key":"17523_CR13","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.pscychresns.2018.08.007","volume":"281","author":"M Davidovic","year":"2018","unstructured":"Davidovic, M. et al. Abnormal brain processing of gentle touch in Anorexia Nervosa. Psychiatry Res. Neuroimaging 281(1), 53\u201360 (2018).","journal-title":"Psychiatry Res. Neuroimaging"},{"issue":"1","key":"17523_CR14","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.psychres.2016.01.078","volume":"239","author":"L Crucianelli","year":"2016","unstructured":"Crucianelli, L., Cardi, V., Treasure, J., Jenkinson, P. M. & Fotopoulou, A. The perception of affective touch in anorexia nervosa. Psychiatry Res. 239(1), 72\u201378 (2016).","journal-title":"Psychiatry Res."},{"key":"17523_CR15","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.neuroscience.2020.09.013","volume":"464","author":"L Crucianelli","year":"2021","unstructured":"Crucianelli, L. et al. The anticipation and perception of affective touch in women with and recovered from anorexia nervosa. Neuroscience 464, 143\u2013155 (2021).","journal-title":"Neuroscience"},{"issue":"8","key":"17523_CR16","first-page":"1","volume":"54","author":"R Ackerley","year":"2014","unstructured":"Ackerley, R., Carlsson, I., Wester, H., Olausson, H. & Backlund Wasling, H. Touch perceptions across skin sites: Differences between sensitivity, direction discrimination and pleasantness. Front. Behav. Neurosci. 54(8), 1\u201310 (2014).","journal-title":"Front. Behav. Neurosci."},{"issue":"8","key":"17523_CR17","doi-asserted-by":"publisher","first-page":"946","DOI":"10.1038\/nn1937","volume":"10","author":"Q Liu","year":"2007","unstructured":"Liu, Q. et al. Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch. Nat. Neurosci. 10(8), 946\u2013948 (2007).","journal-title":"Nat. Neurosci."},{"issue":"4","key":"17523_CR18","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1016\/j.neuron.2014.05.001","volume":"82","author":"F McGlone","year":"2014","unstructured":"McGlone, F., Wessberg, J. & Olausson, H. Discriminative and affective touch: sensing and feeling. Neuron 82(4), 737\u2013755 (2014).","journal-title":"Neuron"},{"issue":"3","key":"17523_CR19","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1002\/cne.1069","volume":"436","author":"CJ Woodbury","year":"2001","unstructured":"Woodbury, C. J., Ritter, A. M. & Koerber, H. R. Central anatomy of individual rapidly adapting low-threshold mechanoreceptors innervating the \u201chairy\u201d skin of newborn mice: early maturation of hair follicle afferents. J. Comp. Neurol. 436(3), 304\u2013323 (2001).","journal-title":"J. Comp. Neurol."},{"issue":"5","key":"17523_CR20","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1038\/nn.2312","volume":"12","author":"LS L\u00f6ken","year":"2009","unstructured":"L\u00f6ken, L. S., Wessberg, J., McGlone, F. & Olausson, H. Coding of pleasant touch by unmyelinated afferents in humans. Nat. Neurosci. 12(5), 547\u2013548 (2009).","journal-title":"Nat. Neurosci."},{"issue":"29","key":"17523_CR21","doi-asserted-by":"publisher","first-page":"9314","DOI":"10.1523\/JNEUROSCI.0400-09.2009","volume":"29","author":"M Bj\u00f6rnsdotter","year":"2009","unstructured":"Bj\u00f6rnsdotter, M., L\u00f6ken, L., Olausson, H., Vallbo, \u00c5. & Wessberg, J. Somatotopic organization of gentle touch processing in the posterior insular cortex. J. Neurosci. 29(29), 9314\u20139320 (2009).","journal-title":"J. Neurosci."},{"issue":"4","key":"17523_CR22","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1002\/hbm.21480","volume":"34","author":"I Gordon","year":"2013","unstructured":"Gordon, I. et al. Brain mechanisms for processing affective touch. Hum. Brain Mapp. 34(4), 914\u2013922 (2013).","journal-title":"Hum. Brain Mapp."},{"issue":"4","key":"17523_CR23","doi-asserted-by":"publisher","first-page":"1308","DOI":"10.1002\/hbm.23103","volume":"37","author":"I Morrison","year":"2016","unstructured":"Morrison, I. ALE meta-analysis reveals dissociable networks for affective and discriminative aspects of touch. Hum. Brain Mapp. 37(4), 1308\u20131320 (2016).","journal-title":"Hum. Brain Mapp."},{"issue":"8","key":"17523_CR24","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1038\/nrn894","volume":"3","author":"AD Craig","year":"2002","unstructured":"Craig, A. D. How do you feel? Interoception: The sense of the physiological condition of the body. Nat. Rev. Neurosci. 3(8), 655\u2013666 (2002).","journal-title":"Nat. Rev. Neurosci."},{"key":"17523_CR25","doi-asserted-by":"publisher","first-page":"1","DOI":"10.7554\/eLife.47895","volume":"9","author":"LP Kirsch","year":"2020","unstructured":"Kirsch, L. P. et al. Damage to the right insula disrupts the perception of affective touch. Elife 9, 1\u201317 (2020).","journal-title":"Elife"},{"issue":"3","key":"17523_CR26","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1007\/s00221-009-2007-y","volume":"204","author":"I Morrison","year":"2010","unstructured":"Morrison, I., L\u00f6ken, L. S. & Olausson, H. The skin as a social organ. Exp. Brain Res. 204(3), 305\u2013314 (2010).","journal-title":"Exp. Brain Res."},{"issue":"2","key":"17523_CR27","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.neubiorev.2008.09.011","volume":"34","author":"H Olausson","year":"2010","unstructured":"Olausson, H., Wessberg, J., McGlone, F. & Vallbo, \u00c5. The neurophysiology of unmyelinated tactile afferents. Neurosci. Biobehav. Rev. 34(2), 185\u2013191 (2010).","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"1","key":"17523_CR28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-019-39168-4","volume":"9","author":"M Carey","year":"2019","unstructured":"Carey, M., Crucianelli, L., Preston, C. & Fotopoulou, A. The effect of visual capture towards subjective embodiment within the full body illusion. Sci. Rep. 9(1), 1\u201312 (2019).","journal-title":"Sci. Rep."},{"key":"17523_CR29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.concog.2020.103059","volume":"87","author":"M Carey","year":"2021","unstructured":"Carey, M., Crucianelli, L., Preston, C. & Fotopoulou, A. The role of affective touch in whole-body embodiment remains equivocal. Conscious. Cogn. 87, 1\u201315 (2021).","journal-title":"Conscious. Cogn."},{"key":"17523_CR30","doi-asserted-by":"publisher","first-page":"e0243680","DOI":"10.1371\/journal.pone.0243680","volume":"16","author":"V Cazzato","year":"2021","unstructured":"Cazzato, V. et al. Affective touch topography and body image. PLoS ONE 16, e0243680 (2021).","journal-title":"PLoS ONE"},{"issue":"7","key":"17523_CR31","doi-asserted-by":"publisher","first-page":"1571","DOI":"10.1093\/brain\/awh500","volume":"128","author":"SJ Blakemore","year":"2005","unstructured":"Blakemore, S. J., Bristow, D., Bird, G., Frith, C. & Ward, J. Somatosensory activations during the observation of touch and a case of vision\u2013touch synaesthesia. Brain 128(7), 1571\u20131583 (2005).","journal-title":"Brain"},{"issue":"9","key":"17523_CR32","doi-asserted-by":"publisher","first-page":"1611","DOI":"10.1162\/jocn.2008.20111","volume":"20","author":"SJ Ebisch","year":"2008","unstructured":"Ebisch, S. J. et al. The sense of touch: embodied simulation in a visuotactile mirroring mechanism for observed animate or inanimate touch. J. Cogn. Neurosci. 20(9), 1611\u20131623 (2008).","journal-title":"J. Cogn. Neurosci."},{"issue":"2","key":"17523_CR33","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1016\/j.neuroimage.2012.01.112","volume":"60","author":"M Schaefer","year":"2012","unstructured":"Schaefer, M., Heinze, H. J. & Rotte, M. Embodied empathy for tactile events: interindividual differences and vicarious somatosensory responses during touch observation. Neuroimage 60(2), 952\u2013957 (2012).","journal-title":"Neuroimage"},{"issue":"4","key":"17523_CR34","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.1093\/brain\/awr011","volume":"134","author":"I Morrison","year":"2011","unstructured":"Morrison, I. et al. Reduced C-afferent fibre density affects perceived pleasantness and empathy for touch. Brain 134(4), 1116\u20131126 (2011).","journal-title":"Brain"},{"key":"17523_CR35","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.bbr.2016.11.046","volume":"320","author":"SC Walker","year":"2017","unstructured":"Walker, S. C., Trotter, P. D., Woods, A. & McGlone, F. Vicarious ratings of social touch reflect the anatomical distribution & velocity tuning of C-tactile afferents: A hedonic homunculus?. Behav. Brain Res. 320, 91\u201396 (2017).","journal-title":"Behav. Brain Res."},{"key":"17523_CR36","doi-asserted-by":"publisher","first-page":"02","DOI":"10.2466\/02.06.20.CP.1.7","volume":"1","author":"K Cooper","year":"2012","unstructured":"Cooper, K. & Mohr, C. Former eating disorder impairs 3rd person but not 1st person perspective taking: does dance training help?. Compr. Psychol. 1, 02\u201306 (2012).","journal-title":"Compr. Psychol."},{"issue":"11","key":"17523_CR37","doi-asserted-by":"publisher","first-page":"2475","DOI":"10.1046\/j.1460-9568.2003.02673.x","volume":"17","author":"P Ruby","year":"2003","unstructured":"Ruby, P. & Decety, J. What you believe versus what you think they believe: a neuroimaging study of conceptual perspective-taking. Eur. J. Neurosci. 17(11), 2475\u20132480 (2003).","journal-title":"Eur. J. Neurosci."},{"issue":"8","key":"17523_CR38","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1002\/eat.22572","volume":"49","author":"E Bora","year":"2016","unstructured":"Bora, E. & K\u00f6se, S. Meta-analysis of theory of mind in anorexia nervosa and bulimia nervosa: A specific impairment of cognitive perspective taking in anorexia nervosa?. Int. J. Eat. Disord. 49(8), 739\u2013740 (2016).","journal-title":"Int. J. Eat. Disord."},{"issue":"1","key":"17523_CR39","first-page":"12","volume":"26","author":"Z G\u00e1l","year":"2011","unstructured":"G\u00e1l, Z., Egyed, K., P\u00e1szthy, B. & N\u00e9meth, D. Impaired theory of mind in anorexia nervosa. Psychiatr. Hung. 26(1), 12\u201325 (2011).","journal-title":"Psychiatr. Hung."},{"key":"17523_CR40","doi-asserted-by":"publisher","first-page":"2527","DOI":"10.2147\/NDT.S116521","volume":"12","author":"S Hamatani","year":"2016","unstructured":"Hamatani, S. et al. Impaired social cognition in anorexia nervosa patients. Neuropsychiatr. Dis. Treat. 12, 2527\u20132531 (2016).","journal-title":"Neuropsychiatr. Dis. Treat."},{"issue":"4","key":"17523_CR41","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1080\/17470919.2020.1760131","volume":"15","author":"G Konstantakopoulos","year":"2020","unstructured":"Konstantakopoulos, G., Ioannidi, N., Patrikelis, P. & Gonidakis, F. Empathy, mentalizing, and cognitive functioning in anorexia nervosa and bulimia nervosa. Soc. Neurosci. 15(4), 477\u2013488 (2020).","journal-title":"Soc. Neurosci."},{"issue":"3","key":"17523_CR42","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/j.psychres.2008.10.028","volume":"168","author":"TA Russell","year":"2009","unstructured":"Russell, T. A., Schmidt, U., Doherty, L., Young, V. & Tchanturia, K. Aspects of social cognition in anorexia nervosa: Affective and cognitive theory of mind. Psychiatry Res. 168(3), 181\u2013185 (2009).","journal-title":"Psychiatry Res."},{"issue":"6","key":"17523_CR43","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1002\/erv.608","volume":"12","author":"K Tchanturia","year":"2004","unstructured":"Tchanturia, K. et al. \u2018Theory of mind\u2019 in anorexia nervosa. Eur. Eating Disord. Rev. 12(6), 361\u2013366 (2004).","journal-title":"Eur. Eating Disord. Rev."},{"issue":"6","key":"17523_CR44","doi-asserted-by":"publisher","first-page":"976","DOI":"10.1037\/0033-2909.133.6.976","volume":"133","author":"NL Zucker","year":"2007","unstructured":"Zucker, N. L. et al. Anorexia nervosa and autism spectrum disorders: Guided investigation of social cognitive endophenotypes. Psychol. Bull. 133(6), 976\u20131006 (2007).","journal-title":"Psychol. Bull."},{"issue":"1","key":"17523_CR45","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.pscychresns.2011.06.016","volume":"194","author":"CJ McAdams","year":"2011","unstructured":"McAdams, C. J. & Krawczyk, D. C. Impaired neural processing of social attribution in anorexia nervosa. Psychiatry Res. Neuroimaging 194(1), 54\u201363 (2011).","journal-title":"Psychiatry Res. Neuroimaging"},{"issue":"2","key":"17523_CR46","doi-asserted-by":"publisher","first-page":"842","DOI":"10.1002\/hbm.23422","volume":"38","author":"H Lee Masson","year":"2017","unstructured":"Lee Masson, H., Wallraven, C. & Petit, L. \u201cCan touch this\u201d: Cross-modal shape categorization performance is associated with microstructural characteristics of white matter association pathways. Hum. Brain Mapp. 38(2), 842\u2013854 (2017).","journal-title":"Hum. Brain Mapp."},{"key":"17523_CR47","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/j.neuroimage.2018.04.007","volume":"175","author":"HL Lee Masson","year":"2018","unstructured":"Lee Masson, H. L., Van De Plas, S., Daniels, N. & de Beeck, H. O. The multidimensional representational space of observed socio-affective touch experiences. Neuroimage 175, 297\u2013314 (2018).","journal-title":"Neuroimage"},{"issue":"8","key":"17523_CR48","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1203\/PDR.0b013e318212c177","volume":"69","author":"B Korkmaz","year":"2011","unstructured":"Korkmaz, B. Theory of mind and neurodevelopmental disorders of childhood. Pediatr. Res. 69(8), 101\u2013108 (2011).","journal-title":"Pediatr. Res."},{"key":"17523_CR49","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.neubiorev.2017.03.017","volume":"77","author":"D Badoud","year":"2017","unstructured":"Badoud, D. & Tsakiris, M. From the body\u2019s viscera to the body\u2019s image: Is there a link between interoception and body image concerns?. Neurosci. Biobehav. Rev. 77, 237\u2013246 (2017).","journal-title":"Neurosci. Biobehav. Rev."},{"key":"17523_CR50","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0048230","volume":"7","author":"WE Mehling","year":"2012","unstructured":"Mehling, W. E. et al. The multidimensional assessment of interoceptive awareness (MAIA). PLoS ONE 7, e48230 (2012).","journal-title":"PLoS ONE"},{"issue":"5","key":"17523_CR51","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1002\/erv.2532","volume":"25","author":"TA Brown","year":"2017","unstructured":"Brown, T. A. et al. Psychometric evaluation and norms for the multidimensional assessment of interoceptive awareness (MAIA) in a clinical eating disorders sample. Eur. Eat. Disord. Rev. 25(5), 411\u2013416 (2017).","journal-title":"Eur. Eat. Disord. Rev."},{"issue":"5","key":"17523_CR52","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1037\/abn0000516","volume":"129","author":"TA Brown","year":"2020","unstructured":"Brown, T. A. et al. Body mistrust bridges interoceptive awareness and eating disorder symptoms. J. Abnorm. Psychol. 129(5), 445\u2013456 (2020).","journal-title":"J. Abnorm. Psychol."},{"issue":"4","key":"17523_CR53","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1007\/s10919-018-0281-8","volume":"42","author":"PD Trotter","year":"2018","unstructured":"Trotter, P. D., McGlone, F., Reniers, R. L. E. P. & Deakin, J. F. W. Construction and validation of the touch experiences and attitudes questionnaire (TEAQ): A self-report measure to determine attitudes toward and experiences of positive touch. J. Nonverbal Behav. 42(4), 379\u2013416 (2018).","journal-title":"J. Nonverbal Behav."},{"issue":"3","key":"17523_CR54","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1002\/erv.2663","volume":"27","author":"S Maier","year":"2019","unstructured":"Maier, S. et al. Neurobiological signature of intimacy in anorexia nervosa. Eur. Eat. Disord. Rev. 27(3), 315\u2013322 (2019).","journal-title":"Eur. Eat. Disord. Rev."},{"issue":"3\u20134","key":"17523_CR55","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1016\/S0022-3999(97)00260-2","volume":"44","author":"L Evans","year":"1998","unstructured":"Evans, L. & Wertheim, E. H. Intimacy patterns and relationship satisfaction of women with eating problems and the mediating effects of depression, trait anxiety and social anxiety. J. Psychosom. Res. 44(3\u20134), 355\u2013365 (1998).","journal-title":"J. Psychosom. Res."},{"issue":"4","key":"17523_CR56","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1002\/1097-4679(199207)48:4<472::AID-JCLP2270480407>3.0.CO;2-#","volume":"48","author":"NA Pruitt","year":"1992","unstructured":"Pruitt, N. A., Kappius, R. E. & Gorman, P. W. Bulimia and fear of intimacy. J. Clin. Psychol. 48(4), 472\u2013476 (1992).","journal-title":"J. Clin. Psychol."},{"key":"17523_CR57","doi-asserted-by":"publisher","DOI":"10.4324\/9781003024262","volume-title":"Appetite: Sex, Touch, and Desire in Women with Anorexia","author":"MA Fabello","year":"2020","unstructured":"Fabello, M. A. Appetite: Sex, Touch, and Desire in Women with Anorexia (Routledge, 2020)."},{"issue":"1","key":"17523_CR58","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1037\/0022-0167.37.1.85","volume":"37","author":"MH Thelen","year":"1990","unstructured":"Thelen, M. H., Farmer, J., Mann, L. M. & Pruitt, J. Bulimia and interpersonal relationships: A longitudinal study. J. Couns. Psychol. 37(1), 85\u201390 (1990).","journal-title":"J. Couns. Psychol."},{"issue":"2","key":"17523_CR59","doi-asserted-by":"publisher","first-page":"175","DOI":"10.3758\/BF03193146","volume":"39","author":"F Faul","year":"2007","unstructured":"Faul, F., Erdfelder, E., Lang, A. G. & Buchner, A. G* Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav. Res. Methods 39(2), 175\u2013191 (2007).","journal-title":"Behav. Res. Methods"},{"key":"17523_CR60","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1016\/j.neubiorev.2019.09.037","volume":"108","author":"V Russo","year":"2020","unstructured":"Russo, V., Ottaviani, C. & Spitoni, G. F. Affective touch: A meta-analysis on sex differences. Neurosci. Biobehav. Rev. 108, 445\u2013452 (2020).","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"5","key":"17523_CR61","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1002\/eat.20625","volume":"42","author":"RH Striegel-Moore","year":"2009","unstructured":"Striegel-Moore, R. H. et al. Gender difference in the prevalence of eating disorder symptoms. Int. J. Eat. Disord. 42(5), 471\u2013474 (2009).","journal-title":"Int. J. Eat. Disord."},{"issue":"1","key":"17523_CR62","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.brat.2004.12.003","volume":"44","author":"JM Mond","year":"2006","unstructured":"Mond, J. M., Hay, P. J., Rodgers, B. & Owen, C. Eating disorder examination questionnaire (EDE-Q): Norms for young adult women. Behav. Res. Ther. 44(1), 53\u201362 (2006).","journal-title":"Behav. Res. Ther."},{"issue":"4","key":"17523_CR63","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1002\/1098-108X(199412)16:4<363::AID-EAT2260160405>3.0.CO;2-#","volume":"16","author":"CG Fairburn","year":"1994","unstructured":"Fairburn, C. G. & Beglin, S. J. Assessment of eating disorders: Interview or self-report questionnaire?. Int. J. Eat. Disord. 16(4), 363\u2013370 (1994).","journal-title":"Int. J. Eat. Disord."},{"issue":"3","key":"17523_CR64","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1002\/(SICI)1098-108X(199904)25:3<349::AID-EAT15>3.0.CO;2-M","volume":"25","author":"KH Luce","year":"1999","unstructured":"Luce, K. H. & Crowther, J. H. The reliability of the eating disorder examination: Self-report questionnaire version (EDE-Q). Int. J. Eat. Disord. 25(3), 349\u2013351 (1999).","journal-title":"Int. J. Eat. Disord."},{"issue":"4","key":"17523_CR65","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1002\/eat.20373","volume":"40","author":"CB Peterson","year":"2007","unstructured":"Peterson, C. B. et al. Psychometric properties of the eating disorder examination-questionnaire: Factor structure and internal consistency. Int. J. Eat. Disord. 40(4), 386\u2013389 (2007).","journal-title":"Int. J. Eat. Disord."},{"issue":"3","key":"17523_CR66","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1002\/eat.20931","volume":"45","author":"KC Berg","year":"2012","unstructured":"Berg, K. C., Peterson, C. B., Frazier, P. & Crow, S. J. Psychometric evaluation of the eating disorder examination and eating disorder examination-questionnaire: A systematic review of the literature. Int. J. Eat. Disord. 45(3), 428\u2013438 (2012).","journal-title":"Int. J. Eat. Disord."},{"issue":"6","key":"17523_CR67","first-page":"1","volume":"120","author":"C Valenzuela-Moguillansky","year":"2015","unstructured":"Valenzuela-Moguillansky, C. & Reyes-Reyes, A. Psychometric properties of the multidimensional assessment of interoceptive awareness (MAIA) in a Chilean population. Front. Psychol. 120(6), 1\u201312 (2015).","journal-title":"Front. Psychol."},{"issue":"12","key":"17523_CR68","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0206905","volume":"13","author":"P Trotter","year":"2018","unstructured":"Trotter, P., Belovol, E., McGlone, F. & Varlamov, A. Validation and psychometric properties of the Russian version of the touch experiences and attitudes questionnaire (TEAQ-37 Rus). PLoS ONE 13(12), e0206905 (2018).","journal-title":"PLoS ONE"},{"issue":"8","key":"17523_CR69","first-page":"1","volume":"1324","author":"R Wacker","year":"2017","unstructured":"Wacker, R., B\u00f6lte, S. & Dziobek, I. Women know better what other women think and feel: Gender effects on mindreading across the adult life span. Front. Psychol. 1324(8), 1\u20137 (2017).","journal-title":"Front. Psychol."},{"issue":"2","key":"17523_CR70","doi-asserted-by":"publisher","first-page":"91","DOI":"10.3758\/BF03327726","volume":"2","author":"NM Henley","year":"1973","unstructured":"Henley, N. M. Status and sex: Some touching observations. Bull. Psychon. Soc. 2(2), 91\u201393 (1973).","journal-title":"Bull. Psychon. Soc."},{"issue":"2","key":"17523_CR71","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1037\/0022-3514.47.2.440","volume":"47","author":"DS Stier","year":"1984","unstructured":"Stier, D. S. & Hall, J. A. Gender differences in touch: An empirical and theoretical review. J. Pers. Soc. Psychol. 47(2), 440\u2013459 (1984).","journal-title":"J. Pers. Soc. Psychol."},{"issue":"3","key":"17523_CR72","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1007\/BF00986945","volume":"7","author":"R Heslin","year":"1983","unstructured":"Heslin, R., Nguyen, T. D. & Nguyen, M. L. Meaning of touch: The case of touch from a stranger or same sex person. J. Nonverbal Behav. 7(3), 147\u2013157 (1983).","journal-title":"J. Nonverbal Behav."},{"key":"17523_CR73","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.paid.2016.11.047","volume":"107","author":"VJ Harjunen","year":"2017","unstructured":"Harjunen, V. J., Spap\u00e9, M., Ahmed, I., Jacucci, G. & Ravaja, N. Individual differences in affective touch: Behavioral inhibition and gender define how an interpersonal touch is perceived. Personality Individ. Differ. 107, 88\u201395 (2017).","journal-title":"Personality Individ. Differ."},{"issue":"1","key":"17523_CR74","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2307\/3001478","volume":"11","author":"DB Duncan","year":"1955","unstructured":"Duncan, D. B. Multiple range and multiple F tests. Biometrics 11(1), 1\u201342 (1955).","journal-title":"Biometrics"},{"issue":"1","key":"17523_CR75","doi-asserted-by":"publisher","first-page":"139","DOI":"10.2307\/2529050","volume":"26","author":"CW Dunnett","year":"1970","unstructured":"Dunnett, C. W. Query: Multiple comparison tests. Biometrics 26(1), 139\u2013141 (1970).","journal-title":"Biometrics"},{"issue":"3","key":"17523_CR76","doi-asserted-by":"publisher","first-page":"203","DOI":"10.11613\/BM.2011.029","volume":"21","author":"ML McHugh","year":"2011","unstructured":"McHugh, M. L. Multiple comparison analysis testing in ANOVA. Biochem. Med. 21(3), 203\u2013209 (2011).","journal-title":"Biochem. Med."},{"key":"17523_CR77","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.bbr.2015.09.038","volume":"297","author":"I Croy","year":"2016","unstructured":"Croy, I. et al. Interpersonal stroking touch is targeted to C tactile afferent activation. Behav. Brain Res. 297, 37\u201340 (2016).","journal-title":"Behav. Brain Res."},{"issue":"1","key":"17523_CR78","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-017-02308-9","volume":"7","author":"EH J\u00f6nsson","year":"2017","unstructured":"J\u00f6nsson, E. H. et al. The relation between human hair follicle density and touch perception. Sci. Rep. 7(1), 1\u201310 (2017).","journal-title":"Sci. Rep."},{"key":"17523_CR79","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.dcn.2017.07.009","volume":"35","author":"I Croy","year":"2019","unstructured":"Croy, I., Sehlstedt, I., Wasling, H. B., Ackerley, R. & Olausson, H. Gentle touch perception: From early childhood to adolescence. Dev. Cogn. Neurosci. 35, 81\u201386 (2019).","journal-title":"Dev. Cogn. Neurosci."},{"issue":"2","key":"17523_CR80","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1016\/j.neubiorev.2009.02.003","volume":"34","author":"GK Essick","year":"2010","unstructured":"Essick, G. K. et al. Quantitative assessment of pleasant touch. Neurosci. Biobehav. Rev. 34(2), 192\u2013203 (2010).","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"2","key":"17523_CR81","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1002\/erv.2271","volume":"22","author":"J Arcelus","year":"2014","unstructured":"Arcelus, J., Witcomb, G. L. & Mitchell, A. Prevalence of eating disorders amongst dancers: A systemic review and meta-analysis. Eur. Eat. Disord. Rev. 22(2), 92\u2013101 (2014).","journal-title":"Eur. Eat. Disord. Rev."},{"issue":"1","key":"17523_CR82","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1521\/jscp.23.1.89.26987","volume":"23","author":"TF Cash","year":"2004","unstructured":"Cash, T. F., Theriault, J. & Annis, N. M. Body image in an interpersonal context: Adult attachment, fear of intimacy and social anxiety. J. Soc. Clin. Psychol. 23(1), 89\u2013103 (2004).","journal-title":"J. Soc. Clin. Psychol."},{"key":"17523_CR83","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.dcn.2017.07.008","volume":"35","author":"U Sailer","year":"2019","unstructured":"Sailer, U. & Ackerley, R. Exposure shapes the perception of affective touch. Dev. Cogn. Neurosci. 35, 109\u2013114 (2019).","journal-title":"Dev. Cogn. Neurosci."},{"issue":"4","key":"17523_CR84","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1207\/s15327752jpa5304_16","volume":"53","author":"SA Shields","year":"1989","unstructured":"Shields, S. A., Mallory, M. E. & Simon, A. The body awareness questionnaire: reliability and validity. J. Pers. Assess. 53(4), 802\u2013815 (1989).","journal-title":"J. Pers. Assess."},{"issue":"3","key":"17523_CR85","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.1016\/j.psychres.2013.08.051","volume":"210","author":"FTP de Sampaio","year":"2013","unstructured":"de Sampaio, F. T. P. et al. Theory of mind and central coherence in eating disorders: Two sides of the same coin?. Psychiatry Res. 210(3), 1116\u20131122 (2013).","journal-title":"Psychiatry Res."},{"issue":"8","key":"17523_CR86","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0044414","volume":"7","author":"M Adenzato","year":"2012","unstructured":"Adenzato, M., Todisco, P. & Ardito, R. B. Social cognition in anorexia nervosa: Evidence of preserved theory of mind and impaired emotional functioning. PLoS ONE 7(8), e44414 (2012).","journal-title":"PLoS ONE"},{"issue":"4","key":"17523_CR87","first-page":"941","volume":"29","author":"RS Calvo","year":"2014","unstructured":"Calvo, R. S. et al. Emotional processing in adult vs adolescent patients with eating behavior disorders, emotional recognizing and the mental theory. Nutr. Hosp. 29(4), 941\u2013952 (2014).","journal-title":"Nutr. Hosp."},{"issue":"2","key":"17523_CR88","first-page":"189","volume":"12","author":"C Medina-Pradas","year":"2012","unstructured":"Medina-Pradas, C., Navarro, J. B., \u00c1lvarez-Moya, E. M., Grau, A. & Obiols, J. E. Emotional theory of mind in eating disorders. Int. J. Clin. Health Psychol. 12(2), 189\u2013202 (2012).","journal-title":"Int. J. Clin. Health Psychol."},{"issue":"318","key":"17523_CR89","first-page":"1","volume":"10","author":"F Sedgewick","year":"2019","unstructured":"Sedgewick, F. et al. Similarities and differences in theory of mind responses of patients with anorexia nervosa with and without autistic features. Front. Psych. 10(318), 1\u201310 (2019).","journal-title":"Front. Psych."},{"key":"17523_CR90","first-page":"1","volume":"6","author":"CG Fairburn","year":"1993","unstructured":"Fairburn, C. G., Cooper, Z. & O\u2019Connor, M. The eating disorder examination. Int. J. Eat. Disord. 6, 1\u20138 (1993).","journal-title":"Int. J. Eat. Disord."},{"key":"17523_CR91","unstructured":"Fairburn, C. G., Cooper, Z., & O\u2019Connor, M. Eating disorder examination (Edition 16.0 D). in Cognitive Behavior Therapy and Eating Disorders, 265\u2013308 (Springer, 2008)."},{"key":"17523_CR92","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.cortex.2016.03.021","volume":"81","author":"P Shah","year":"2016","unstructured":"Shah, P., Hall, R., Catmur, C. & Bird, G. Alexithymia, not autism, is associated with impaired interoception. Cortex 81, 215\u2013220 (2016).","journal-title":"Cortex"},{"issue":"3","key":"17523_CR93","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/S0301-0511(01)00113-2","volume":"58","author":"FH Wilhelm","year":"2001","unstructured":"Wilhelm, F. H., Kochar, A. S., Roth, W. T. & Gross, J. J. Social anxiety and response to touch: Incongruence between self-evaluative and physiological reactions. Biol. Psychol. 58(3), 181\u2013202 (2001).","journal-title":"Biol. Psychol."},{"issue":"1","key":"17523_CR94","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1001\/archpsyc.1983.01790010081010","volume":"40","author":"J Fawcett","year":"1983","unstructured":"Fawcett, J., Clark, D. C., Scheftner, W. A. & Gibbons, R. D. Assessing anhedonia in psychiatric patients: The pleasure scale. Arch. Gen. Psychiatry 40(1), 79\u201384 (1983).","journal-title":"Arch. Gen. Psychiatry"},{"issue":"1","key":"17523_CR95","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1192\/bjp.167.1.99","volume":"167","author":"RP Snaith","year":"1995","unstructured":"Snaith, R. P. et al. A scale for the assessment of hedonic tone the Snaith-Hamilton Pleasure Scale. Br. J. Psychiatry 167(1), 99\u2013103 (1995).","journal-title":"Br. J. Psychiatry"},{"key":"17523_CR96","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1016\/j.jad.2018.12.054","volume":"246","author":"C Triscoli","year":"2019","unstructured":"Triscoli, C., Croy, I. & Sailer, U. Depression predicts interpersonal problems partially through the attitude towards social touch. J. Affect. Disord. 246, 234\u2013240 (2019).","journal-title":"J. Affect. Disord."},{"issue":"3\u20134","key":"17523_CR97","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1080\/17470910600985605","volume":"1","author":"JT Kaplan","year":"2006","unstructured":"Kaplan, J. T. & Iacoboni, M. Getting a grip on other minds: Mirror neurons, intention understanding, and cognitive empathy. Soc. Neurosci. 1(3\u20134), 175\u2013183 (2006).","journal-title":"Soc. Neurosci."},{"issue":"1","key":"17523_CR98","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.biopsych.2008.08.006","volume":"65","author":"I Minio-Paluello","year":"2009","unstructured":"Minio-Paluello, I., Baron-Cohen, S., Avenanti, A., Walsh, V. & Aglioti, S. M. Absence of embodied empathy during pain observation in Asperger syndrome. Biol. Psychiat. 65(1), 55\u201362 (2009).","journal-title":"Biol. Psychiat."},{"issue":"1","key":"17523_CR99","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1080\/17405629.2014.950221","volume":"12","author":"P Rueda","year":"2015","unstructured":"Rueda, P., Fern\u00e1ndez-Berrocal, P. & Baron-Cohen, S. Dissociation between cognitive and affective empathy in youth with Asperger Syndrome. Eur. J. Dev. Psychol. 12(1), 85\u201398 (2015).","journal-title":"Eur. J. Dev. Psychol."},{"issue":"5","key":"17523_CR100","doi-asserted-by":"publisher","first-page":"802","DOI":"10.3758\/s13415-016-0432-5","volume":"16","author":"L Peled-Avron","year":"2016","unstructured":"Peled-Avron, L., Levy-Gigi, E., Richter-Levin, G., Korem, N. & Shamay-Tsoory, S. G. The role of empathy in the neural responses to observed human social touch. Cogn. Affect. Behav. Neurosci. 16(5), 802\u2013813 (2016).","journal-title":"Cogn. Affect. Behav. Neurosci."},{"issue":"1","key":"17523_CR101","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1080\/13546805.2013.794723","volume":"19","author":"R Morris","year":"2014","unstructured":"Morris, R., Bramham, J., Smith, E. & Tchanturia, K. Empathy and social functioning in anorexia nervosa before and after recovery. Cogn. Neuropsychiatry 19(1), 47\u201357 (2014).","journal-title":"Cogn. Neuropsychiatry"},{"issue":"3","key":"17523_CR102","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/S0022-3999(01)00314-2","volume":"52","author":"A Hilbert","year":"2002","unstructured":"Hilbert, A., Tuschen-Caffier, B. & V\u00f6gele, C. Effects of prolonged and repeated body image exposure in binge-eating disorder. J. Psychosom. Res. 52(3), 137\u2013144 (2002).","journal-title":"J. Psychosom. Res."},{"key":"17523_CR103","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.cpr.2018.08.006","volume":"65","author":"TC Griffen","year":"2018","unstructured":"Griffen, T. C., Naumann, E. & Hildebrandt, T. Mirror exposure therapy for body image disturbances and eating disorders: A review. Clin. Psychol. Rev. 65, 163\u2013174 (2018).","journal-title":"Clin. Psychol. Rev."}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-022-17523-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-022-17523-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-022-17523-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T05:19:15Z","timestamp":1669353555000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-022-17523-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,4]]},"references-count":103,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["17523"],"URL":"https:\/\/doi.org\/10.1038\/s41598-022-17523-2","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,4]]},"assertion":[{"value":"3 December 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 July 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 August 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"13429"}}