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Control of Dengue vectors largely depends upon synthetic pyrethroids. Development of insecticide resistance in\n                    <jats:italic>Aedes<\/jats:italic>\n                    mosquitoes however, poses severe threat to insecticide-based vector management programme. Mutations in the Voltage Gated Sodium Channel gene (\n                    <jats:italic>vgsc<\/jats:italic>\n                    ) serve as the primary machinery behind this resistance development. In\n                    <jats:italic>Aedes albopictus<\/jats:italic>\n                    , at least four such kdr (knock down resistance) mutations had already been documented. Here, we describe the occurrence of F1534C kdr mutation in wild population of\n                    <jats:italic>Ae. albopictus<\/jats:italic>\n                    from northern part of West Bengal, India including a novel T1520I mutation. Four populations of\n                    <jats:italic>Ae. albopictus<\/jats:italic>\n                    from the studied region were found resistant against DDT and synthetic pyrethroids, among them only one population possessed F1534C kdr mutation. A total of 200 successful amplification followed by partial sequencing of\n                    <jats:italic>vgsc<\/jats:italic>\n                    gene further revealed the presence of F1534C kdr mutation in both phenotypically susceptible and resistant mosquito specimen. Studied populations were found 81% homozygote susceptible (1534F\/F), 12.5% heterozygote (1534F\/C) and 6% homozygote resistant (1534C\/C) for F1534C kdr mutation. The findings of the current study will help to uncover the mechanisms underlying insecticide resistance and hence to reduce errors in vector control measurements.\n                  <\/jats:p>","DOI":"10.1038\/s41598-022-17739-2","type":"journal-article","created":{"date-parts":[[2022,8,11]],"date-time":"2022-08-11T06:04:19Z","timestamp":1660197859000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["First report of F1534C kdr mutation in deltamethrin resistant Aedes albopictus from northern part of West Bengal, India"],"prefix":"10.1038","volume":"12","author":[{"given":"Manas Pratim","family":"Modak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhiraj","family":"Saha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,8,11]]},"reference":[{"issue":"8","key":"17739_CR1","doi-asserted-by":"publisher","first-page":"988","DOI":"10.1016\/S2214-109X(19)30249-9","volume":"7","author":"A Wilder-Smith","year":"2019","unstructured":"Wilder-Smith, A. & Rupali, P. 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