{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T03:31:23Z","timestamp":1789097483780,"version":"build-2803163510"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T00:00:00Z","timestamp":1664409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T00:00:00Z","timestamp":1664409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To compare pelvic organ prolapse (POP) recurrence and morbidity between first and second line sacrocolpopexies. We conducted a retrospective chart review of all laparoscopic or robotic sacrocolpopexies for POP-Q stage<jats:bold>\u2009\u2265\u2009<\/jats:bold>2, with or without a history of previous prolapse repair, performed with a similar technique between January 2012 and June 2019 in 3 European Gynecologic Surgery Departments. Patients were separated into two groups: first line sacrocolpopexy (FLS) and second line sacrocolpopexy (SLS). Each patient from the SLS group was age-matched with a patient from the FLS group. The primary outcome measure was reoperation procedures for recurrent POP defined as a symptomatic POP-Q stage\u2009\u2265\u20092 POP in at least one vaginal compartment. Secondary outcomes included operative time, intraoperative organ trauma, intraoperative blood loss, postoperative POP recurrence (operated on or not), global reoperation and mesh-related complications. During this period, 332 patients were included. After age-matching, 170 patients were analyzed: 85 patients in the FLS and SLS groups, respectively. After a mean follow-up of 3\u00a0years, there was no statistically significant difference between the two groups in terms of recurrent POP (9.4% versus 10.6%, p\u2009=\u20090.7), recurrent POP reoperation (3.5% versus 5.9% p\u2009=\u20090.7), mesh-related reoperation (0% versus 2.4%, p\u2009=\u20090.5), global reoperation (3.5 versus 8.2%, p\u2009=\u20090.3), operative time (198\u2009\u00b1\u200967\u00a0min versus 193\u2009\u00b1\u200960\u00a0min, p\u2009=\u20090.5), intraoperative complications such as organ injury (4.7% versus 7.1%, p\u2009=\u20090.7) and blood loss\u2009&gt;\u2009500\u00a0mL (2.4% versus 0%, p\u2009=\u20090.5). Patients who underwent a first or a second line sacrocolpopexy seemed to have similar rates of prolapse recurrence and complications.<\/jats:p>","DOI":"10.1038\/s41598-022-20127-5","type":"journal-article","created":{"date-parts":[[2022,9,29]],"date-time":"2022-09-29T10:02:43Z","timestamp":1664445763000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Comparison of first versus second line sacrocolpopexies in terms of morbidity and mid-term efficacy"],"prefix":"10.1038","volume":"12","author":[{"given":"Marine","family":"Lallemant","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. T. M.","family":"Grob","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Puyraveau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. A. 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Cosson receives honoraria and reports participation in a speaker's bureau for Boston Scientific, Vivacy and Mediron companies. The other authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"16283"}}