{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T02:54:08Z","timestamp":1794020048595,"version":"4.8.0"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,10,6]],"date-time":"2022-10-06T00:00:00Z","timestamp":1665014400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,10,6]],"date-time":"2022-10-06T00:00:00Z","timestamp":1665014400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["442522\/2019-3"],"award-info":[{"award-number":["442522\/2019-3"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005672","name":"Funda\u00e7\u00e3o de Apoio ao Desenvolvimento do Ensino, Ci\u00eancia e Tecnologia do Estado de Mato Grosso do Sul","doi-asserted-by":"publisher","award":["03\/2016"],"award-info":[{"award-number":["03\/2016"]}],"id":[{"id":"10.13039\/501100005672","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Human T-lymphotropic viruses 1 and 2 (HTLV-1\/2) have a worldwide distribution. HTLV-1 has been associated with several diseases, including an aggressive malignant disease known as adult T-cell leukemia\/lymphoma and a chronic inflammatory neurological disease called HTLV-1-associated myelopathy, while HTLV-2 has not been definitively associated with diseases. HTLV-2 is most prevalent in specific groups such as injecting drug users and the indigenous population. In Brazil, most studies about HTLV in indigenous are carried out in indigenous communities from the north of the country. Mato Grosso do Sul (MS), Central Brazil, has the second-largest indigenous population in Brazil. However, there is no available data about HTLV infection in this group. We conducted the first investigation of HTLV-1\/2 infection prevalence in the indigenous population from Jaguapiru and Boror\u00f3 villages in Dourados City, MS, to provide the prevalence and molecular characterization of HTLV. For that, a total of 1875 indigenous participated in the study. All the serum samples were screened by an enzyme-linked immunosorbent assay commercial kit for the presence of anti-HTLV-1\/2 antibodies. Positive samples were confirmed by HTLV-1\/2 Western Blot assay. The HTLV-1 5\u2019LTR region was detected by nested PCR amplification and sequenced by Sanger. Most of the study population declared belonging to Guarani-Kaiow\u00e1 ethnicity (69.18%), 872 (46.51%), and 1003 (53.49%) were from Jaguapiru and Boror\u00f3 villages, respectively. The median age of participants was 31\u00a0years, and 74.24% were females. Two individuals were detected with HTLV-1 (0.1%; CI 95% 0.1\u20130.2). The phylogenetic analysis revealed that isolates belong to the Cosmopolitan subtype and the Transcontinental subgroup (HTLV-1aA). The low HTLV-1 prevalence found in this study is similar to that observed among blood donors, and pregnant populations from Mato Grosso do Sul. The absence of HTLV-2 infection among these Brazilian indigenous communities would suggest a distinct behavior pattern from other indigenous populations in Brazil.<\/jats:p>","DOI":"10.1038\/s41598-022-21086-7","type":"journal-article","created":{"date-parts":[[2022,10,6]],"date-time":"2022-10-06T10:02:29Z","timestamp":1665050549000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["HTLV infection in Brazil\u2019s second-largest indigenous reserve"],"prefix":"10.1038","volume":"12","author":[{"given":"Carolina","family":"Amianti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa Melo","family":"Bandeira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela Alves","family":"Cesar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina","family":"Weis-Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tayana Serpa Ortiz","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Indianara Ramires","family":"Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crhistinne Cavalheiro Maymone","family":"Gon\u00e7alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Simionatto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica Cristina dos Santos","family":"Schnaufer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe Bonfim","family":"Freitas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio Carlos Ros\u00e1rio","family":"Vallinoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio","family":"Croda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Rita Coimbra","family":"Motta-Castro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,10,6]]},"reference":[{"issue":"1","key":"21086_CR1","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1186\/s12879-019-4041-0","volume":"19","author":"I Bra\u00e7o","year":"2019","unstructured":"Bra\u00e7o, I. et al. High prevalence of human T-lymphotropic virus 2 (HTLV-2) infection in villages of the Xikrin tribe (Kayapo), Brazilian Amazon region. BMC Infect. Dis. 19(1), 459. https:\/\/doi.org\/10.1186\/s12879-019-4041-0 (2019).","journal-title":"BMC Infect. Dis."},{"key":"21086_CR2","unstructured":"Garnelo, L. Sa\u00fade Ind\u00edgena: Uma introdu\u00e7\u00e3o ao tema. Luiza Garnelo; Ana L\u00facia Pontes (2012). Bras\u00edlia: MEC-SECADI, 280 p. il. Color. (Cole\u00e7\u00e3o Educa\u00e7\u00e3o para Todos) ISBN 978-85-7994-063-7."},{"key":"21086_CR3","doi-asserted-by":"publisher","first-page":"71","DOI":"10.11606\/S1518-8787.2019053000362","volume":"53","author":"SV Graeff","year":"2019","unstructured":"Graeff, S. V., P\u00edcolli, R. P., Arantes, R., Castro, V. & Cunha, R. Epidemiological aspects of HIV infection and AIDS among indigenous populations. Rev. Saude Publica 53, 71. https:\/\/doi.org\/10.11606\/S1518-8787.2019053000362 (2019).","journal-title":"Rev. Saude Publica"},{"key":"21086_CR4","doi-asserted-by":"publisher","first-page":"17","DOI":"10.26633\/RPSP.2019.17","volume":"43","author":"NK Russell","year":"2019","unstructured":"Russell, N. K. et al. HIV, syphilis, and viral hepatitis among Latin American indigenous peoples and Afro-descendants: A systematic review. Rev. Panam. Salud Publica Pan Am. J. Public Health 43, 17. https:\/\/doi.org\/10.26633\/RPSP.2019.17 (2019).","journal-title":"Rev. Panam. Salud Publica Pan Am. J. Public Health"},{"issue":"1","key":"21086_CR5","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1186\/s12939-017-0589-8","volume":"16","author":"AS Benzaken","year":"2017","unstructured":"Benzaken, A. S. et al. HIV and syphilis in the context of community vulnerability among indigenous people in the Brazilian Amazon. Int. J. Equity Health 16(1), 92. https:\/\/doi.org\/10.1186\/s12939-017-0589-8 (2017).","journal-title":"Int. J. Equity Health"},{"issue":"5","key":"21086_CR6","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1353\/hub.2002.0059","volume":"74","author":"AC Vallinoto","year":"2002","unstructured":"Vallinoto, A. C. et al. Molecular epidemiology of human T-lymphotropic virus type II infection in Amerindian and urban populations of the Amazon region of Brazil. Hum. Biol. 74(5), 633\u2013644. https:\/\/doi.org\/10.1353\/hub.2002.0059 (2002).","journal-title":"Hum. Biol."},{"key":"21086_CR7","unstructured":"BRASIL. IBGE. Instituto Brasileiro de Geografia Estat\u00edstica. Os ind\u00edgenas no Censo Demogr\u00e1fico 2010 primeiras considera\u00e7\u00f5es com base no quesito cor ou ra\u00e7a (Rio de Janeiro, 2012). https:\/\/indigenas.ibge.gov.br\/images\/indigenas\/estudos\/indigena_censo2010.pdf."},{"key":"21086_CR8","unstructured":"SECID\/MS. Subsecretaria Especial de Cidadania. Governo do Estado de Mato Grosso do Sul. https:\/\/www.secid.ms.gov.br\/comunidades-indigenas-2\/."},{"issue":"3","key":"21086_CR9","first-page":"305","volume":"99","author":"MLB de Alcantara","year":"2020","unstructured":"de Alcantara, M. L. B., Moure, W., Trajber, Z., Machado, I. R., Equipe de Jovens da A\u00e7\u00e3o dos Jovens Ind\u00edgenas de Dourados-MS. A percep\u00e7\u00e3o do suic\u00eddio como insepar\u00e1vel das outras formas de viol\u00eancia segundo os\/as jovens ind\u00edgenas: Um estudo de caso da Reserva Ind\u00edgena de Dourados. Rev. Med. 99(3), 305\u2013318 (2020).","journal-title":"Rev. Med."},{"key":"21086_CR10","unstructured":"Mota, J. G. B. & Cavalcante, T. L. V. Reserva Ind\u00edgena de Dourados: Hist\u00f3rias e Desafios Contempor\u00e2neos, 285 (Karywa, 2019). ISBN: 978\u201385\u201368730\u201338\u20136."},{"key":"21086_CR11","doi-asserted-by":"publisher","first-page":"15012","DOI":"10.1038\/nrdp.2015.12","volume":"1","author":"CR Bangham","year":"2015","unstructured":"Bangham, C. R., Araujo, A., Yamano, Y. & Taylor, G. P. HTLV-1-associated myelopathy\/tropical spastic paraparesis. Nat. Rev. Dis. Primers 1, 15012. https:\/\/doi.org\/10.1038\/nrdp.2015.12 (2015).","journal-title":"Nat. Rev. Dis. Primers"},{"issue":"2","key":"21086_CR12","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1007\/s12325-018-0658-4","volume":"35","author":"O Hermine","year":"2018","unstructured":"Hermine, O., Ramos, J. C. & Tobinai, K. A review of new findings in adult T-cell leukemia-lymphoma: A focus on current and emerging treatment strategies. Adv. Ther. 35(2), 135\u2013152. https:\/\/doi.org\/10.1007\/s12325-018-0658-4 (2018).","journal-title":"Adv. Ther."},{"issue":"1","key":"21086_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1590\/S0036-46652015000100001","volume":"57","author":"A Paiva","year":"2015","unstructured":"Paiva, A. & Casseb, J. Origin and prevalence of human T-lymphotropic virus type 1 (HTLV-1) and type 2 (HTLV-2) among indigenous populations in the Americas. Rev. Inst. Med. Trop. Sao Paulo 57(1), 1\u201313. https:\/\/doi.org\/10.1590\/S0036-46652015000100001 (2015).","journal-title":"Rev. Inst. Med. Trop. Sao Paulo"},{"issue":"1","key":"21086_CR14","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/s12977-019-0483-0","volume":"16","author":"MP Martinez","year":"2019","unstructured":"Martinez, M. P., Al-Saleem, J. & Green, P. L. Comparative virology of HTLV-1 and HTLV-2. Retrovirology 16(1), 21. https:\/\/doi.org\/10.1186\/s12977-019-0483-0 (2019).","journal-title":"Retrovirology"},{"issue":"1","key":"21086_CR15","doi-asserted-by":"publisher","first-page":"14750","DOI":"10.1038\/s41598-019-51383-7","volume":"9","author":"AB Oliveira-Filho","year":"2019","unstructured":"Oliveira-Filho, A. B. et al. Human T-lymphotropic virus 1 and 2 among people who used illicit drugs in the state of Par\u00e1, northern Brazil. Sci. Rep. 9(1), 14750. https:\/\/doi.org\/10.1038\/s41598-019-51383-7 (2019).","journal-title":"Sci. Rep."},{"issue":"9","key":"21086_CR16","doi-asserted-by":"publisher","first-page":"e0009717","DOI":"10.1371\/journal.pntd.0009717","volume":"15","author":"C Rosadas","year":"2021","unstructured":"Rosadas, C. et al. Blocking HTLV-1\/2 silent transmission in Brazil: Current public health policies and proposal for additional strategies. PLoS Negl. Trop. Dis. 15(9), e0009717. https:\/\/doi.org\/10.1371\/journal.pntd.0009717 (2021).","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"7","key":"21086_CR17","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1089\/aid.1995.11.813","volume":"11","author":"R Ishak","year":"1995","unstructured":"Ishak, R. et al. Identification of human T cell lymphotropic virus type IIa infection in the Kayapo, an indigenous population of Brazil. AIDS Res. Hum. Retrovir. 11(7), 813\u2013821. https:\/\/doi.org\/10.1089\/aid.1995.11.813 (1995).","journal-title":"AIDS Res. Hum. Retrovir."},{"issue":"6","key":"21086_CR18","doi-asserted-by":"publisher","first-page":"1947","DOI":"10.1590\/s0102-311x2005000600045","volume":"21","author":"M Menna-Barreto","year":"2005","unstructured":"Menna-Barreto, M. et al. Human T-cell lymphotropic virus type II in Guaran\u00ed Indians, Southern Brazil. Cad. Saude Publica 21(6), 1947\u20131951. https:\/\/doi.org\/10.1590\/s0102-311x2005000600045 (2005).","journal-title":"Cad. Saude Publica"},{"issue":"2","key":"21086_CR19","doi-asserted-by":"publisher","first-page":"7","DOI":"10.5123\/s2176-62232017000200001","volume":"8","author":"ACR Vallinoto","year":"2017","unstructured":"Vallinoto, A. C. R. & Ishak, R. HTLV-2: Uma infec\u00e7\u00e3o antiga entre os povos ind\u00edgenas da Amaz\u00f4nia brasileira. Rev. Pan Amaz. Saude Ananindeua 8(2), 7\u20139. https:\/\/doi.org\/10.5123\/s2176-62232017000200001 (2017).","journal-title":"Rev. Pan Amaz. Saude Ananindeua"},{"issue":"1","key":"21086_CR20","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1089\/088922202753394736","volume":"18","author":"N Shindo","year":"2002","unstructured":"Shindo, N. et al. Human retroviruses (HIV and HTLV) in Brazilian Indians: Seroepidemiological study and molecular epidemiology of HTLV type 2 isolates. AIDS Res. Hum. Retrovir. 18(1), 71\u201377. https:\/\/doi.org\/10.1089\/088922202753394736 (2002).","journal-title":"AIDS Res. Hum. Retrovir."},{"issue":"8","key":"21086_CR21","doi-asserted-by":"publisher","first-page":"700","DOI":"10.2174\/1570162x11209080700","volume":"10","author":"EH de Oliveira","year":"2012","unstructured":"de Oliveira, E. H. et al. Human T-cell lymphotropic virus in patients infected with HIV-1: Molecular epidemiology and risk factors for transmission in Piaui, Northeastern Brazil. Curr. HIV Res. 10(8), 700\u2013707. https:\/\/doi.org\/10.2174\/1570162x11209080700 (2012).","journal-title":"Curr. HIV Res."},{"key":"21086_CR22","unstructured":"Freitas, G. M. B. Estudo Cl\u00ednico e Epidemiol\u00f3gico da Infec\u00e7\u00e3o pelos V\u00edrus Linfotr\u00f3picos de C\u00e9lulas-T Humanas (HTLV-I\/II) em Doadores de Sangue em Campo Grande-MS (1994\u20132001). (Doctoral dissertation, Disserta\u00e7\u00e3o de mestrado, Funda\u00e7\u00e3o Oswalddo Cruz, Rio de Janeiro, 2002)."},{"issue":"2","key":"21086_CR23","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1590\/s0037-86822008000200003","volume":"41","author":"MMFJ Dal Fabbro","year":"2008","unstructured":"Dal Fabbro, M. M. F. J. et al. HTLV 1\/2 infection: Prenatal performance as a disease control strategy in State of Mato Grosso do Sul. Rev. Soc. Bras. Med. Trop. 41(2), 148\u2013151. https:\/\/doi.org\/10.1590\/s0037-86822008000200003 (2008).","journal-title":"Rev. Soc. Bras. Med. Trop."},{"issue":"4","key":"21086_CR24","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1590\/s0102-311x2003000400013","volume":"19","author":"R Ishak","year":"2003","unstructured":"Ishak, R., Vallinoto, A. C., Azevedo, V. N. & Ishak, M. Epidemiological aspects of retrovirus (HTLV) infection among Indian populations in the Amazon Region of Brazil. Cad. Sa\u00fade Publica 19(4), 901\u2013914. https:\/\/doi.org\/10.1590\/s0102-311x2003000400013 (2003).","journal-title":"Cad. Sa\u00fade Publica"},{"issue":"5","key":"21086_CR25","doi-asserted-by":"publisher","first-page":"855","DOI":"10.3390\/v13050855","volume":"13","author":"L Machado","year":"2021","unstructured":"Machado, L. et al. The epidemiological impact of STIs among general and vulnerable populations of the Amazon Region of Brazil: 30 years of surveillance. Viruses 13(5), 855. https:\/\/doi.org\/10.3390\/v13050855 (2021).","journal-title":"Viruses"},{"issue":"14","key":"21086_CR26","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1089\/088922299310124","volume":"15","author":"T Fujiyoshi","year":"1999","unstructured":"Fujiyoshi, T. et al. Characteristic distribution of HTLV type I and HTLV type II carriers among native ethnic groups in South America. AIDS Res. Hum. Retrovir. 15(14), 1235\u20131239. https:\/\/doi.org\/10.1089\/088922299310124 (1999).","journal-title":"AIDS Res. Hum. Retrovir."},{"issue":"2","key":"21086_CR27","doi-asserted-by":"publisher","first-page":"veaa053","DOI":"10.1093\/ve\/veaa053","volume":"6","author":"R Ishak","year":"2020","unstructured":"Ishak, R. et al. HTLV in South America: Origins of a silent ancient human infection. Virus Evol. 6(2), veaa053. https:\/\/doi.org\/10.1093\/ve\/veaa053 (2020).","journal-title":"Virus Evol."},{"issue":"4","key":"21086_CR28","doi-asserted-by":"publisher","first-page":"e0003691","DOI":"10.1371\/journal.pntd.0003691","volume":"9","author":"LM Bandeira","year":"2015","unstructured":"Bandeira, L. M. et al. High prevalence of HTLV-1 infection among Japanese immigrants in non-endemic area of Brazil. PLoS Negl. Trop. Dis. 9(4), e0003691. https:\/\/doi.org\/10.1371\/journal.pntd.0003691 (2015).","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"6","key":"21086_CR29","doi-asserted-by":"publisher","first-page":"657","DOI":"10.1590\/s0037-86822009000600009","volume":"42","author":"LB Nascimento","year":"2009","unstructured":"Nascimento, L. B. et al. Preval\u00eancia da infec\u00e7\u00e3o pelo HTLV-1, em remanescentes de quilombos no Brasil Central [Prevalence of infection due to HTLV-1 in remnant quilombos in Central Brazil]. Rev. Soc. Bras. Med. Trop. 42(6), 657\u2013660. https:\/\/doi.org\/10.1590\/s0037-86822009000600009 (2009).","journal-title":"Rev. Soc. Bras. Med. Trop."},{"issue":"8","key":"21086_CR30","doi-asserted-by":"publisher","first-page":"897","DOI":"10.1016\/j.arcmed.2007.05.002","volume":"38","author":"LIB Kanzaki","year":"2007","unstructured":"Kanzaki, L. I. B. & Casseb, J. Unusual finding of HTLV-I infection among Amazonian Amerindians. Arch. Med. Res. 38(8), 897\u2013900. https:\/\/doi.org\/10.1016\/j.arcmed.2007.05.002 (2007).","journal-title":"Arch. Med. Res."},{"key":"21086_CR31","unstructured":"BRASIL. Instituto Brasileiro de Geografia e Estat\u00edstica (Cidades e Estados Dourados, 2022). https:\/\/www.ibge.gov.br\/cidades-e-estados\/ms\/dourados.html."},{"issue":"5","key":"21086_CR32","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1159\/000441240","volume":"8","author":"GF Oliveira","year":"2015","unstructured":"Oliveira, G. F. et al. Prevalence of obesity and overweight in an indigenous population in central Brazil: A population-based cross-sectional study. Obes. Facts 8(5), 302\u2013310. https:\/\/doi.org\/10.1159\/000441240 (2015).","journal-title":"Obes. Facts"},{"key":"21086_CR33","doi-asserted-by":"publisher","first-page":"833169","DOI":"10.3389\/fpubh.2022.833169","volume":"10","author":"IN Abreu","year":"2022","unstructured":"Abreu, I. N. et al. HTLV-1 and HTLV-2 infection among Warao indigenous refugees in the Brazilian Amazon: Challenges for public health in times of increasing migration. Front. Public Health 10, 833169. https:\/\/doi.org\/10.3389\/fpubh.2022.833169 (2022).","journal-title":"Front. Public Health"},{"key":"21086_CR34","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1016\/j.ijid.2020.07.037","volume":"99","author":"L Zanella","year":"2020","unstructured":"Zanella, L. et al. Phylogenetic dating analysis of HTLV-1 from Chile suggests transmissions events related to ancient migrations and contemporary expansion. Int. J. Infect. Dis. 99, 186\u2013189. https:\/\/doi.org\/10.1016\/j.ijid.2020.07.037 (2020).","journal-title":"Int. J. Infect. Dis."},{"key":"21086_CR35","doi-asserted-by":"publisher","first-page":"198687","DOI":"10.1016\/j.virusres.2022.198687","volume":"311","author":"L Zanella","year":"2022","unstructured":"Zanella, L. et al. Genome analysis suggests HTLV-1aA introduction in Chile related to migrations of ancestral indigenous populations. Virus Res. 311, 198687. https:\/\/doi.org\/10.1016\/j.virusres.2022.198687 (2022).","journal-title":"Virus Res."},{"issue":"9","key":"21086_CR36","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1089\/aid.1994.10.1165","volume":"10","author":"FL Black","year":"1994","unstructured":"Black, F. L., Biggar, R. J., Neel, J. V., Maloney, E. M. & Waters, D. J. Endemic transmission of HTLV type II among Kayapo Indians of Brazil. AIDS Res. Hum. Retrovir. 10(9), 1165\u20131171. https:\/\/doi.org\/10.1089\/aid.1994.10.1165 (1994).","journal-title":"AIDS Res. Hum. Retrovir."},{"issue":"3","key":"21086_CR37","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1590\/s0102-311x2005000300027","volume":"21","author":"B Catalan-Soares","year":"2005","unstructured":"Catalan-Soares, B., Carneiro-Proietti, A. B., Proietti, F. A., Interdisciplinary HTLV Research Group. Heterogeneous geographic distribution of human T-cell lymphotropic viruses I and II (HTLV-I\/II): Serological screening prevalence rates in blood donors from large urban areas in Brazil. Cad. A\u00fade Publica 21(3), 926\u2013931. https:\/\/doi.org\/10.1590\/s0102-311x2005000300027 (2005).","journal-title":"Cad. A\u00fade Publica"}],"container-title":["Scientific Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.nature.com\/articles\/s41598-022-21086-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-022-21086-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.nature.com\/articles\/s41598-022-21086-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,6]],"date-time":"2022-10-06T10:03:55Z","timestamp":1665050635000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.nature.com\/articles\/s41598-022-21086-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,6]]},"references-count":37,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,12]]}},"alternative-id":["21086"],"URL":"https:\/\/doi.org\/10.1038\/s41598-022-21086-7","relation":{},"ISSN":["2045-2322"],"issn-type":[{"value":"2045-2322","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,6]]},"assertion":[{"value":"13 April 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 September 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 October 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"16701"}}