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Patients underwent ophthalmic evaluation before surgery, including optical biometry with IOLMaster 500. Same exams were repeated 2\u00a0months after surgery: AL of operated eye was evaluated using two modes (pseudophakic\/aphakic options). Mean Keratometry and AL changes were analyzed. Furthermore, refractive prediction error (PE) was back-calculated with Barrett Universal-II, Hoffer-Q, Holladay-1 and SRK\/T formulas. To eliminate any systematic error, the mean error (ME) was zeroed-out for each formula. MEs and median absolute errors (MedAEs) of PEs were analyzed. Two-hundred-one operated eyes of 201 patients and 201 opposite eyes were evaluated. In operated eyes, mean AL difference was \u2212 0.11\u2009\u00b1\u20090.07\u00a0mm (p\u2009&lt;\u20090.001) with pseudophakic option and 0.00\u2009\u00b1\u20090.07\u00a0mm (p\u2009=\u20090.922) with aphakic option. There were not-statistically significant differences between MedAE of PEs calculated after zeroing-out the ME with different ALs (p\u2009&gt;\u20090.05). Instead, only MEs of PEs obtained with postoperative ALs-pseudophakic option were not-statistically different from zero (p\u2009&gt;\u20090.05). AL measurement change after cataract surgery is probably due to a systematic error in optical biometer in case of phakic eyes. A correction factor applied to preoperative AL could eliminate any systematic error in IOL power calculation without modifying the lens constant.<\/jats:p>","DOI":"10.1038\/s41598-022-23665-0","type":"journal-article","created":{"date-parts":[[2022,11,7]],"date-time":"2022-11-07T11:40:50Z","timestamp":1667821250000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["A formula to improve the reliability of optical axial length measurement in IOL power calculation"],"prefix":"10.1038","volume":"12","author":[{"given":"Maddalena","family":"De Bernardo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferdinando","family":"Cione","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Capasso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessia","family":"Coppola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Rosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,11,7]]},"reference":[{"key":"23665_CR1","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/S0886-3350(88)80059-2","volume":"14","author":"JT Holladay","year":"2002","unstructured":"Holladay, J. 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