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To date, the suggested solutions to excessive monitoring alarms have remained on a research level. We aimed to identify patient characteristics that affect the ICU alarm rate with the goal of proposing a straightforward solution that can easily be implemented in ICUs. Alarm logs from eight adult ICUs of a tertiary care university-hospital in Berlin, Germany were retrospectively collected between September 2019 and March 2021. Adult patients admitted to the ICU with at least 24\u00a0h of continuous alarm logs were included in the study. The sum of alarms per patient per day was calculated. The median was 119. A total of 26,890 observations from 3205 patients were included. 23 variables were extracted from patients' electronic health records (EHR) and a multivariable logistic regression was performed to evaluate the association of patient characteristics and alarm rates. Invasive blood pressure monitoring (adjusted odds ratio (aOR) 4.68, 95%CI 4.15\u20135.29, p\u2009&lt;\u20090.001), invasive mechanical ventilation (aOR 1.24, 95%CI 1.16\u20131.32, p\u2009&lt;\u20090.001), heart failure (aOR 1.26, 95%CI 1.19\u20131.35, p\u2009&lt;\u20090.001), chronic renal failure (aOR 1.18, 95%CI 1.10\u20131.27, p\u2009&lt;\u20090.001), hypertension (aOR 1.19, 95%CI 1.13\u20131.26, p\u2009&lt;\u20090.001), high RASS (aOR 1.22, 95%CI 1.18\u20131.25, p\u2009&lt;\u20090.001) and scheduled surgical admission (aOR 1.22, 95%CI 1.13\u20131.32, p\u2009&lt;\u20090.001) were significantly associated with a high alarm rate. Our study suggests that patient-specific alarm management should be integrated in the clinical routine of ICUs. To reduce the overall alarm load, particular attention regarding alarm management should be paid to patients with invasive blood pressure monitoring, invasive mechanical ventilation, heart failure, chronic renal failure, hypertension, high RASS or scheduled surgical admission since they are more likely to have a high contribution to noise pollution, alarm fatigue and hence compromised patient safety in ICUs.<\/jats:p>","DOI":"10.1038\/s41598-022-26261-4","type":"journal-article","created":{"date-parts":[[2022,12,16]],"date-time":"2022-12-16T18:02:51Z","timestamp":1671213771000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["The influence of patient characteristics on the alarm rate in intensive care units: a retrospective cohort study"],"prefix":"10.1038","volume":"12","author":[{"given":"Zeena-Carola","family":"Sinno","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denys","family":"Shay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen","family":"Kruppa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie A.I.","family":"Klopfenstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niklas","family":"Giesa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Rike","family":"Flint","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Herren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franziska","family":"Scheibe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Spies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl","family":"Hinrichs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"Winter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Balzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira-Sebastian","family":"Poncette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,12,16]]},"reference":[{"issue":"10","key":"26261_CR1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0110274","volume":"9","author":"BJ Drew","year":"2014","unstructured":"Drew, B. 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