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Firstly, Fe<jats:sub>3<\/jats:sub>O<jats:sub>4<\/jats:sub> NPs were synthesized by FeCl<jats:sub>3<\/jats:sub>.6H<jats:sub>2<\/jats:sub>O and FeCl<jats:sub>2<\/jats:sub>.4H<jats:sub>2<\/jats:sub>O according to the reported method, and subsequently, the prepared MNP with 3-chloropropyltrimethoxysilane. After that, the support-glycerol was functionalized on the surface of MNP-(CH<jats:sub>2<\/jats:sub>)<jats:sub>3<\/jats:sub>Cl for graft and stabilization of copper metal. Our purpose is to use the Fe<jats:sub>3<\/jats:sub>O<jats:sub>4<\/jats:sub>@Glycerol-Cu as a green, recoverable, novel, and affordable nanocatalyst in the effective synthesis of 2-amino-4<jats:italic>H<\/jats:italic>-chromenes. FT-IR, XRD, TGA, BET, VSM, TEM, and SEM\u2013EDX techniques were examined to characterize this nanocatalyst. This result demonstrates that copper and organic compounds have appropriately reacted, with the support of MNP-(CH<jats:sub>2<\/jats:sub>)<jats:sub>3<\/jats:sub>Cl, and the crystalline structure have preserved in the MNP-(CH<jats:sub>2<\/jats:sub>)<jats:sub>3<\/jats:sub>Cl\/Glycerol-Cu nanocatalyst confirmed the formation of the base Cu complex grafted on the surface of the nanoparticles. Finally, as can be seen, the nanoparticle size is 5\u201315\u00a0nm. This heterogeneous nanocatalyst illustrated excellent recyclable behavior, and can be used several times without notable reduction of its activity.<\/jats:p>","DOI":"10.1038\/s41598-022-26769-9","type":"journal-article","created":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T17:04:23Z","timestamp":1671728663000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Fe3O4@Glycerol-Cu as a novel heterogeneous magnetic nanocatalyst for the green synthesis of 2-amino-4H-chromenes"],"prefix":"10.1038","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5899-4285","authenticated-orcid":false,"given":"Ahmad","family":"Poursattar Marjani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0365-6537","authenticated-orcid":false,"given":"Fatemeh","family":"Asadzadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2162-7411","authenticated-orcid":false,"given":"Aria","family":"Danandeh Asl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,12,22]]},"reference":[{"key":"26769_CR1","doi-asserted-by":"crossref","unstructured":"Nasir Baig, R. 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