{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,14]],"date-time":"2026-11-14T03:29:17Z","timestamp":1794626957787,"version":"4.9.1"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T00:00:00Z","timestamp":1704240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T00:00:00Z","timestamp":1704240000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Sci Rep"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Suspicious architectural distortion is an elusive finding in breast cancer diagnosis. This study aimed to evaluate the diagnostic accuracy of the Kaiser score for suspicious architectural distortions observed on mammography and compare it with the BI-RADS score of the lesion. Mammograms performed between January 2013 and March 2023 were retrospectively analyzed for the presence of suspicious architectural distortion. Forty-one patients, who had at least 1\u00a0year of radiological follow-up or pathology results, and underwent breast MRI, were included in the study. Mammography findings and the BI-RADS category of the lesion were assessed. MRI findings were evaluated and Kaiser scoring was performed according to the tree flowchart. Ninety-one percent of the enhanced lesions had a Kaiser score of 5 and above. In the diagnosis of malignancy, the Kaiser score yielded an accuracy of 75.61% (AUC 0.833). A statistically significant correlation was observed indicating that a malignant diagnosis was more prevalent in patients with a Kaiser score of 5 and above (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). Additionally statistically significant relationship was also observed between the BI-RADS category of architectural distortions on mammography and the Kaiser score (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.007). The combined utilization of mammography findings and the evidence-based Kaiser score in suspected architectural distortions provides more accurate results in the differential diagnosis of breast cancer.\n                  <\/jats:p>","DOI":"10.1038\/s41598-023-50798-7","type":"journal-article","created":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T15:03:26Z","timestamp":1704294206000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Diagnostic accuracy of the breast MRI Kaiser score in suspected architectural distortions and its comparison with mammography"],"prefix":"10.1038","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6935-1472","authenticated-orcid":false,"given":"Ozge","family":"Aslan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0209-5878","authenticated-orcid":false,"given":"Aysenur","family":"Oktay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,1,3]]},"reference":[{"issue":"1","key":"50798_CR1","doi-asserted-by":"publisher","first-page":"216","DOI":"10.2214\/AJR.13.11047","volume":"203","author":"L Partyka","year":"2014","unstructured":"Partyka, L., Lourenco, A. P. & Mainiero, M. B. Detection of mammographically occult architectural distortion on digital breast tomosynthesis screening: Initial clinical experience. AJR Am. J. Roentgenol. 203(1), 216\u2013222 (2014).","journal-title":"AJR Am. J. Roentgenol."},{"issue":"6","key":"50798_CR2","doi-asserted-by":"publisher","first-page":"728","DOI":"10.1038\/s41379-021-00996-3","volume":"35","author":"SE Bachert","year":"2022","unstructured":"Bachert, S. E. et al. Breast lesions associated with mammographic architectural distortion: A study of 588 core needle biopsies. Mod. Pathol. 35(6), 728\u2013738 (2022).","journal-title":"Mod. Pathol."},{"issue":"1","key":"50798_CR3","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s00330-017-4968-8","volume":"28","author":"EH Dibble","year":"2018","unstructured":"Dibble, E. H. et al. Comparison of digital mammography and digital breast tomosynthesis in the detection of architectural distortion. Eur. Radiol. 28(1), 3\u201310 (2018).","journal-title":"Eur. Radiol."},{"issue":"6","key":"50798_CR4","doi-asserted-by":"publisher","first-page":"1397","DOI":"10.2214\/AJR.18.19658","volume":"211","author":"C Vijapura","year":"2018","unstructured":"Vijapura, C., Yang, L., Xiong, J. & Fajardo, L. L. Imaging features of nonmalignant and malignant architectural distortion detected by tomosynthesis. AJR Am. J. Roentgenol. 211(6), 1397\u20131404 (2018).","journal-title":"AJR Am. J. Roentgenol."},{"issue":"11","key":"50798_CR5","doi-asserted-by":"publisher","first-page":"1216","DOI":"10.1055\/a-1829-5985","volume":"194","author":"PAT Baltzer","year":"2022","unstructured":"Baltzer, P. A. T., Krug, K. B. & Dietzel, M. Evidence-based and structured diagnosis in breast MRI using the kaiser score: Evidenzbasierte und strukturierte diagnostik in der MR-Mammografie anhand des Kaiser-Score. Rofo 194(11), 1216\u20131228 (2022).","journal-title":"Rofo"},{"issue":"3","key":"50798_CR6","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1007\/s13244-018-0611-8","volume":"9","author":"M Dietzel","year":"2018","unstructured":"Dietzel, M. & Baltzer, P. A. T. How to use the Kaiser score as a clinical decision rule for diagnosis in multiparametric breast MRI: A pictorial essay. Insights Imaging 9(3), 325\u2013335 (2018).","journal-title":"Insights Imaging"},{"issue":"4","key":"50798_CR7","doi-asserted-by":"publisher","first-page":"322","DOI":"10.5152\/dir.2022.201075","volume":"28","author":"Q Wang","year":"2022","unstructured":"Wang, Q. et al. Application of the Kaiser score by MRI in patients with breast lesions by ultrasound and mammography. Diagn. Interv. Radiol. 28(4), 322\u2013328 (2022).","journal-title":"Diagn. Interv. Radiol."},{"issue":"11","key":"50798_CR8","doi-asserted-by":"publisher","first-page":"6052","DOI":"10.1007\/s00330-020-06945-z","volume":"30","author":"RI Milos","year":"2020","unstructured":"Milos, R. I. et al. The Kaiser score reliably excludes malignancy in benign contrast-enhancing lesions classified as BI-RADS 4 on breast MRI high-risk screening exams. Eur. Radiol. 30(11), 6052\u20136061 (2020).","journal-title":"Eur. Radiol."},{"issue":"10","key":"50798_CR9","doi-asserted-by":"publisher","first-page":"6384","DOI":"10.21037\/qims-23-113","volume":"13","author":"H Wang","year":"2023","unstructured":"Wang, H., Gao, L., Chen, X. & Wang, S. J. Quantitative evaluation of Kaiser score in diagnosing breast dynamic contrast-enhanced magnetic resonance imaging for patients with high-grade background parenchymal enhancement. Quant Imaging Med. Surg. 13(10), 6384\u20136394 (2023).","journal-title":"Quant Imaging Med. Surg."},{"key":"50798_CR10","doi-asserted-by":"publisher","first-page":"109659","DOI":"10.1016\/j.ejrad.2021.109659","volume":"138","author":"A Istomin","year":"2021","unstructured":"Istomin, A., Masarwah, A., Vanninen, R., Okuma, H. & Sudah, M. Diagnostic performance of the Kaiser score for characterizing lesions on breast MRI with comparison to a multiparametric classification system. Eur J Radiol. 138, 109659 (2021).","journal-title":"Eur J Radiol."},{"key":"50798_CR11","unstructured":"American College of Radiology. ACR BI-RADS Atlas: Breast Imaging Reporting And Data System. 5th ed. Virginia: Reston; 2013."},{"key":"50798_CR12","unstructured":"http:\/\/www.meduniwien.ac.at\/kaiser-score\/ Accessed 15 Jul 2023."},{"issue":"4","key":"50798_CR13","doi-asserted-by":"publisher","first-page":"579","DOI":"10.4274\/dir.2022.221790","volume":"29","author":"A Oktay","year":"2023","unstructured":"Oktay, A. et al. Outcomes of high-risk breast lesions diagnosed using image-guided core needle biopsy: Results from a multicenter retrospective study. Diagn Interv Radiol. 29(4), 579\u2013587 (2023).","journal-title":"Diagn Interv Radiol."},{"issue":"39","key":"50798_CR14","doi-asserted-by":"publisher","first-page":"e17061","DOI":"10.1097\/MD.0000000000017061","volume":"98","author":"H Tan","year":"2019","unstructured":"Tan, H., Zhang, H., Lei, Z., Fu, F. & Wang, M. Radiological and clinical findings in sclerosing adenosis of the breast. Medicine 98(39), e17061 (2019).","journal-title":"Medicine"},{"issue":"3","key":"50798_CR15","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1007\/s00330-019-06444-w","volume":"30","author":"GJ Wengert","year":"2020","unstructured":"Wengert, G. J. et al. Impact of the Kaiser score on clinical decision-making in BI-RADS 4 mammographic calcifications examined with breast MRI. Eur. Radiol. 30(3), 1451\u20131459 (2020).","journal-title":"Eur. 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